1. The pathology and pathogenesis of dislocations and fracture-dislocations of the cervical spine has been reviewed.

2. A method of treatment using skeletal traction and manipulation under relaxant general anaesthesia is described. Results of treatment are given for all patients admitted to the Centre with flexion-rotation dislocations of the cervical spine complicated by neurological lesions, between November 1961 and December 1968.

3. After reviewing the literature and considering the results obtained in seventy-six cases, we advocate a policy of conservative management with gentle manipulation of the cervical spine in selected cases, reduction being maintained thereafter by skeletal traction. We reserve operation for the few cases that demonstrate late instability or for those rarer cases in which manipulation fails and the patient has either an incomplete neurological lesion or a double skeletal injury.

4. The low incidence of late instability after adequate conservative treatment is stressed, and the danger of overdistraction of the cervical spine by heavy traction in patients with severe ligamentous damage is emphasised.

1. The long-term results in a consecutive series of 323 healed subcapital fractures of the femur show that, with few exceptions, the capital fragment maintains its integrity when the fragments are aligned within the narrow limits of good reduction, but undergoes superior segmental collapse when reduction is poor.

2. The effect of malreduction on the congruity of the hip joint is examined, and a remodelling response to malalignment of the aspherical femoral head in the imperfectly round acetabulum is proposed as an alternative interpretation of the radiological changes now considered to be the result of capital ischaemia.

1. A series of thirty-two cases of chondromyxoid fibroma is reported.

2. The clinical, radiographic and pathological features are described.

3. The rarity of the tumour and of malignant change is stressed.

4. Excision or block resection is preferred to curettage as a method of treatment, because of the liability to recurrence after curettage.

5. It is suggested that the designation "fibromyxoid chondroma" is more appropriate than the usual designation "chondromyxoid fibroma".

Halo pelvic traction, a method of correcting the deformed spine, is discussed and experience with treatment of our first twenty-five patients presented.

1. Five patients are reported in whom osteochondritis is shown to have given rise to anterior intervertebral fusion.

2. It is suggested that anterior intervertebral fusion discovered in radiographs of adult spines may arise from osteochondritis rather than from a congenital abnormality or infection.

1. The results in 138 hands operated on for Dupuytren's contracture are analysed and compared with those in other series.

2. Contracture ofthe metacarpo-phalangeal joint can be expected to respond well to operation, whereas the outlook in the case of contracture of the proximal interphalangeal joint is generally poor.

3. The reasons for this difference are examined.

4. The advantages of early operation for contracture of the proximal interphalangeal joint are stressed.

1. The pedigree of a family in which lobster claw foot and triphalangeal thumb occurred together is presented. The affected members of two generations are described. The clinical appearances and radiological abnormalities are described in detail. Results of surgical treatment of the forefoot cleft are presented.

2. Lobster clawing of the foot is discussed with particular reference to associated hand and finger abnormalities. Triphalangeal thumb is discussed. The current and probably acceptable theory of the etiology of duplication is expanded. A hypothesis is formulated of excessive activity at the pre-and post-axial borders of the distal limb bud, followed by variable resorption, to explain not only the cause of lobster claw foot but also its occurrence in association with triphalangeal thumb.

1. One hundred and eighty-one fractures of the tibial shaft were treated by rigid fixation using conventional plates.

2. Comparison is made with series of fractures treated by the closed method.

3. The incidence of non-union, or delayed union requiring a long period of plaster immobilisation, was found to be less with the open method of treatment.

4. Plating was also found to give better functional results with a shorter period of disability except in severe open fractures.

5. Plating is a valuable method of treatment for tibial fractures in the elderly.

1. A concept and design of polycentric knee arthroplasty based on the biomechanics of normal knee movement is presented. The diseased articular surfaces of the femoral condyles and tibial plateaus are replaced separately by prosthetic implants secured with cement. The collateral and cruciate ligaments are retained to maintain joint stability.

2. The early results from this arthroplasty in twenty-two knees are assessed. The operation gave relief of pain in twenty-two, a range of movement greater than 90 degrees in thirteen, no lateral instability in sixteen of twenty-two knees and an increased degree of mobility for nineteen of twenty individuals (two bilateral arthroplasties).

3. Operative complications consisted of delayed wound healing in four knees and common peroneal nerve palsy in one. One knee was subsequently arthrodesed for lack of functional improvement.

1. A twenty-six-year-old woman was paraplegic because of a benign giant-cell tumour which had destroyed the body of the twelfth thoracic vertebra completely and the bodies of the eleventh thoracic and first lumbar vertebrae partially. The tumour had expanded into both pleural cavities and displaced the aorta forward and to the left. The extent and topography of the tumour were evaluated before operation by angiography. The function of the spinal cord had not been improved significantly by laminectomy. It was therefore decided to attempt extirpation of the tumour by removing all remaining parts of the three vertebrae involved.

2. After the removal of the tumour, only the spinal cord with the thecal sac bridged the gap between the tenth thoracic and second lumbar vertebrae. The gap was bridged with struts of cortical bone from both tibiae and with two strong plates, all secured with steel wire. The metal was removed five months later because it had become loose. Gradual shortening and angulation of the spine then occurred, together with progressive resorption of the cortical grafts. Nevertheless, the operation restored the function of the spinal cord; the patient regained ability to walk and full control of the bladder.

1. A forty-nine-year-old man had a chondrosarcoma arising from the body of the seventh thoracic vertebra. The tumour protruded into the mediastinum and also into the spinal canal where it displaced the spinal cord.

2. At operation all the seventh thoracic vertebra and parts of the sixth and eighth were removed together with the tumour. The thoracic spine was reconstructed by inserting two iliac bone-blocks between the cut bodies of the sixth and eighth vertebrae and by wiring two strong "A. O." plates to the transverse processes of the third to the sixth and the eighth to the tenth vertebrae.

3. The patient was nursed in a plaster-of-Paris bed for three and a half months.

4. One year and three months after operation, the patient was walking and well, with no signs of recurrence or metastasis. Radiographs showed that a block-vertebra had been created from the iliac grafts and the two cut vertebrae.

1. Four joints of three young haemophiliacs who died in traffic accidents have been examined.

2. All patients had received prompt specific treatment for intra-articular and other haemorrhages.

3. Major macroscopic and histological changes were seen in the joints, but these changes were not quite so severe as those described before the days of specific treatment.

4. The possibilities of preventing articular changes and of minimising the effect of blood in the joints are discussed.

Four cases are presented of patients seen in a leper colony in South Vietnam. The patients presented with evidence of osteolysis, arthropathies and severe scarrings of the skin. They were without pain and in generally good health. There were no neurologic or vascular deficit. They had positive serological tests for syphilis. Other known types of osteolysis are discussed including leprosy and the treponemal diseases, and the cases are presented as a previously undescribed entity.

The case histories of two brothers with congenital defects of the tibia and neurofibromatosis are presented. This report of congenital pseudarthrosis of the tibia in siblings is believed to be the first in the English literature.

From the experimental evidence above, it is clear that in the upper four centimetres of the forearm the posterior interosseous nerve moves up to one centimetre or more medially relative to the radius on pronation of the forearm. This movement becomes of importance when considered in relation to methods of operative approach for excision of the radial head.

Operative approaches have been described in which emphasis has been placed on the position of incision, but in none of these is there any mention of the position of the forearm.

We suggest that the following precautions should be taken. 1) During excision of the radial head the forearm should be kept in full pronation. 2) The incision should be as posterior as possible to ensure that it is well clear of the nerve. 3) With the forearm pronated the incision extends from a little above the lateral epicondyle along the postero-lateral aspect of the forearm for not more than 5 centimetres; proportionately less in a child. 4) The surgical assistant's attention should be brought to the damage that the posterior interosseous nerve might sustain from undue pressure–for instance by retraction, especially by bone levers–in the anterior part of the wound.

1. Degenerative arthritis has been produced consistently in adult rabbits by the injection of the proteolytic plant enzyme papain into the hip joint. Arthritic changes were recognisable radiographically after six weeks.

2. A progression of changes occurred, from loss of acid mucopolysaccharide staining in the matrix, fibrillation, fissuring and erosion of articular cartilage with death of chondrocytes in the weight-bearing areas, to secondary bony changes of subchondral sclerosis, occasional cysts and osteophyte formation.

3. Synovial inflammation occurred with accumulation of cartilage and bone debris in the inferior capsule and later capsular thickening.

4. It is suggested that this arthritis is sufficiently similar to human osteoarthritis to be useful as a model for further studies of the pathogenesis of the disease and the effects of different methods of treatment.