header advert
Results 1 - 2 of 2
Results per page:
The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 12 | Pages 1666 - 1669
1 Dec 2006
Shisha T Kiss S Pap K Simpson H Szöke G

The response of the muscle is critical in determining the functional outcome of limb lengthening. We hypothesised that muscle response would vary with age and therefore studied the response of the muscles during tibial lengthening in ten young and ten mature rabbits. A bromodeoxyuridine technique was used to identify the dividing cells.

The young rabbits demonstrated a significantly greater proliferative response to the distraction stimulus than the mature ones. This was particularly pronounced at the myotendinous junction, but was also evident within the muscle belly.

Younger muscle adapted better to lengthening, suggesting that in patients in whom a large degree of muscle lengthening is required it may be beneficial to carry out this procedure when they are young, in order to achieve the optimal functional result.

The Journal of Bone & Joint Surgery British Volume
Vol. 86-B, Issue 7 | Pages 958 - 961
1 Sep 2004
Dreinhöfer KE Féron J Herrera A Hube R Johnell O Lidgren L Miles K Panarella L Simpson H Wallace WA