The Bone & Joint Journal
Vol. 100-B, Issue 6 | Pages 703 - 711
1 Jun 2018
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The aim of this review was to evaluate the available literature
and to calculate the pooled sensitivity and specificity for the
different alpha-defensin test systems that may be used to diagnose
prosthetic joint infection (PJI). Studies using alpha-defensin or Synovasure (Zimmer Biomet, Warsaw,
Indiana) to diagnose PJI were identified from systematic searches
of electronic databases. The quality of the studies was evaluated
using the Quality Assessment of Studies of Diagnostic Accuracy (QUADAS)
tool. Meta-analysis was completed using a bivariate model.Aims
Materials and Methods
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