1. Of forty-seven patients with histologically proven myeloma of the spine, thirty-three had multiple lesions at the time of the first examination and fourteen were solitary.

2. Five of the solitary cases, in which the patients are alive and well without signs of dissemination four to fourteen years after diagnosis, are considered in detail and the differences in clinical presentation and prognosis are discussed.

3. A sixth case, described in detail, showed scattered osteolytic lesions after ten years.

1. The case history of a haemophiliac in whom a large haematoma of the thigh was treated by amputation of the limb is described.

2. Examination of the available radiographs and of the histology led to the conclusion that the cyst was subperiosteal in origin.

3. Evidence is presented to support the hypothesis that haemophilic pseudotumours are always associated with subperiosteal haemorrhage, and that those haemophilic cysts which are confined to muscle have little or no effect on the adjacent bone.