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The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 4 | Pages 583 - 587
1 May 2002
van der Sluijs JA van Ouwerkerk WJR de Gast A Wuisman P Nollet F Manoliu RA

We undertook a prospective MRI study to measure the retroversion of the humeral head in 33 consecutive infants with a mean age of 1 year 10 months (3 months to 7 years 4 months) who had an obstetric brachial plexus lesion (OBPL). According to a standardised MRI protocol both shoulders and humeral condyles were examined and the shape of the glenoid and humeral retroversion determined. The mean humeral retroversion of the affected shoulder was significantly increased compared with the normal contralateral side (−28.4 ± 12.5° v −21.5 ± 15.1°, p = 0.02). This increase was found only in the children over the age of 12 months. In this group humeral retroversion was −29.9 ± 12.9° compared with −19.6 ± 15.6° in the normal shoulder (p = 0.009), giving a mean difference of 10.3° (95% confidence interval 3.3 to 17.3). This finding is of importance when considering the operative treatment for subluxation of the shoulder in children with an OBPL


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 4 | Pages 551 - 535
1 May 2001
van der Sluijs JA van Ouwerkerk WJR de Gast A Wuisman PIJM Nollet F Manoliu RA

We performed a prospective study using MRI in 16 consecutive infants with a mean age of 5.2 months (2.7 to 8.7) who had shown inadequate recovery from an obstetric lesion of the brachial plexus in the first three months of life, in order to identify early secondary deformities of the shoulder. Shoulders were analysed according to a standardised MRI protocol. Measurements were made of the appearance of the glenoid, glenoid version and the position of the humeral head. The appearance of the glenoid on the affected side was normal in only seven shoulders. In the remainder it was convex in seven and bioconcave in three. The degree of subluxation of the humeral head was significantly greater (p = 0.01) in the affected shoulders than in normal shoulders (157° v 170°). The presence of an abnormal appearance of the glenoid, retroversion of the glenoid and subluxation of the humeral head increased with age. There was a statistical difference (p = 0.05) between infants younger than five months and those who were older


The Journal of Bone & Joint Surgery British Volume
Vol. 66-B, Issue 3 | Pages 337 - 339
1 May 1984
Pazzaglia U Byers P

This paper reports a singular case of pathological fracture through a large osteolytic lesion of the mid-femur consequent on reaction to a hip prosthesis. Not only metal particles but also polyethylene fibres were found at this site, some 15 cm from the prosthesis. The case sheds an interesting light on the reaction to prostheses


The Bone & Joint Journal
Vol. 96-B, Issue 11 | Pages 1540 - 1545
1 Nov 2014
Dierselhuis EF van den Eerden PJM Hoekstra HJ Bulstra SK Suurmeijer AJH Jutte PC

Atypical cartilaginous tumours are usually treated by curettage. The purpose of this study was to show that radiofrequency ablation was an effective alternative treatment.

We enrolled 20 patients (two male, 18 female, mean age 56 years (36 to 72) in a proof-of-principle study. After inclusion, biopsy and radiofrequency ablation were performed, followed three months later by curettage and adjuvant phenolisation. The primary endpoint was the proportional necrosis in the retrieved material. Secondary endpoints were correlation with the findings on gadolinium enhanced MRI, functional outcome and complications.

Our results show that 95% to 100% necrosis was obtained in 14 of the 20 patients. MRI had a 91% sensitivity and 67% specificity for detecting residual tumour after curettage. The mean functional outcome (MSTS) score six weeks after radiofrequency ablation was 27.1 (23 to 30) compared with 18.1 (12 to 25) after curettage (p < 0.001). No complications occurred after ablation, while two patients developed a pathological fracture after curettage.

We have shown that radiofrequency ablation is capable of completely eradicating cartilaginous tumour cells in selective cases. MRI has a 91% sensitivity for detecting any residual tumour. Radiofrequency ablation can be performed on an outpatient basis allowing a rapid return to normal activities. If it can be made more effective, it has the potential to provide better local control, while improving functional outcome.

Cite this article: Bone Joint J 2014;96-B:1540–5.


The Bone & Joint Journal
Vol. 101-B, Issue 7 | Pages 824 - 831
1 Jul 2019
Mahmoud EE Adachi N Mawas AS Deie M Ochi M

Aim

Mesenchymal stem cells (MSCs) have several properties that may support their use as an early treatment option for osteoarthritis (OA). This study investigated the role of multiple injections of allogeneic bone marrow-derived stem cells (BMSCs) to alleviate the progression of osteoarthritic changes in the various structures of the mature rabbit knee in an anterior cruciate ligament (ACL)-deficient OA model.

Materials and Methods

Two months after bilateral section of the ACL of Japanese white rabbits aged nine months or more, either phosphate buffered saline (PBS) or 1 x 106 MSCs were injected into the knee joint in single or three consecutive doses. After two months, the articular cartilage and meniscus were assessed macroscopically, histologically, and immunohistochemically using collagen I and II.


The Journal of Bone & Joint Surgery British Volume
Vol. 77-B, Issue 1 | Pages 162 - 163
1 Jan 1995
Bonney G


The Journal of Bone & Joint Surgery British Volume
Vol. 73-B, Issue 5 | Pages 870 - 870
1 Sep 1991
Pazzaglia U


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 5 | Pages - 747
1 May 2005
Aichroth P


The Journal of Bone & Joint Surgery British Volume
Vol. 75-B, Issue 2 | Pages 331 - 332
1 Mar 1993
Mosheiff R Robin G Mattan Y Sucher E


The Journal of Bone & Joint Surgery British Volume
Vol. 33-B, Issue 4 | Pages 604 - 605
1 Nov 1951
Dwyer FC


The Journal of Bone & Joint Surgery British Volume
Vol. 86-B, Issue 5 | Pages 777 - 777
1 Jul 2004
GIBBS JR RICKETTS D


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 2 | Pages 320 - 320
1 Mar 1990
Crawfurd E Emery R Aichroth P


The Journal of Bone & Joint Surgery British Volume
Vol. 71-B, Issue 3 | Pages 534 - 534
1 May 1989
Rae P Noble J


The Journal of Bone & Joint Surgery British Volume
Vol. 64-B, Issue 4 | Pages 405 - 408
1 Aug 1982
Jepson K Nada A Rymaszewski L


The Journal of Bone & Joint Surgery British Volume
Vol. 35-B, Issue 1 | Pages 83 - 83
1 Feb 1953
Richmond DA


The Journal of Bone & Joint Surgery British Volume
Vol. 85-B, Issue 3 | Pages 462 - 462
1 Apr 2003
BEAULÉ PE


The Journal of Bone & Joint Surgery British Volume
Vol. 73-B, Issue 3 | Pages 498 - 500
1 May 1991
Stoker D Cobb J Pringle J

Needle biopsies, performed on 208 consecutive patients and interpreted at the London Bone Tumour Service over a two-year period, were reviewed. A correct diagnosis was reached in 97% (133 out of 137) using this technique alone. Needle biopsy is safe and accurate when undertaken in consultation within a bone tumour service; it offers considerable advantages to both patient and surgeon over conventional open biopsy.


The Journal of Bone & Joint Surgery British Volume
Vol. 61-B, Issue 2 | Pages 190 - 193
1 May 1979
Spector D Miller J Viloria J


The Journal of Bone & Joint Surgery British Volume
Vol. 53-B, Issue 2 | Pages 310 - 313
1 May 1971
Jones PG


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 6 | Pages 916 - 920
1 Aug 2001
Schenker M Birch R

The precise point of intradural rupture in preganglionic traction injuries to the brachial plexus has been a subject of controversy. In this study of avulsed roots we have shown that rupture occurs at varying levels. True avulsion of the root with attached spinal cord tissue was seen in two cases and in the remainder rupture was peripheral to the central-peripheral transition zone. We have further shown that corpora amylacea marked the boundary between tissue of the central and peripheral nervous systems. This observation provides a basis for renewed work towards the direct repair of intradural ruptures of the ventral and dorsal roots.