The aim of this consensus was to develop a definition of post-operative
fibrosis of the knee. An international panel of experts took part in a formal consensus
process composed of a discussion phase and three Delphi rounds.Aims
Patients and Methods
This prospective randomised controlled trial was designed to
evaluate the outcome of both the MRI- and CT-based patient-specific
matched guides (PSG) from the same manufacturer. A total of 137 knees in 137 patients (50 men, 87 women) were
included, 67 in the MRI- and 70 in the CT-based PSG group. Their
mean age was 68.4 years (47.0 to 88.9). Outcome was expressed as
the biomechanical limb alignment (centre hip-knee-ankle: HKA-axis)
achieved post-operatively, the position of the individual components
within 3° of the pre-operatively planned alignment, correct planned
implant size and operative data (e.g. operating time and blood loss).Aims
Patients and Methods
The December 2015 Knee Roundup360 looks at: Albumin and complications in knee arthroplasty; Tantalum: a knee fixation for all seasons?; Dynamic knee alignment; Tibial component design in UKA; Managing the tidal wave of revision knee arthroplasty; Scoring pain in TKR; Does anyone have a ‘normal’ tibial slope?; XLPE in TKR? A five-year clinical study; Spacers and infected revision arthroplasties; Dialysis and arthroplasty
The October 2015 Knee Roundup360 looks at: Allergy and outcome in arthroplasty; Physiotherapy and drains not such a bad combination?; Another nail in the coffin for arthroscopists?; Graft precondition hocus pocus; Extended dose steroids in knee arthritis?; Indolent peri-prosthetic infection; Computer modelling and medial knee arthritis
Unicompartmental knee arthroplasty (UKA) has
advantages over total knee arthroplasty but national joint registries report
a significantly higher revision rate for UKA. As a result, most
surgeons are highly selective, offering UKA only to a small proportion
(up to 5%) of patients requiring arthroplasty of the knee, and consequently
performing few each year. However, surgeons with large UKA practices
have the lowest rates of revision. The overall size of the practice
is often beyond the surgeon’s control, therefore case volume may
only be increased by broadening the indications for surgery, and
offering UKA to a greater proportion of patients requiring arthroplasty
of the knee. The aim of this study was to determine the optimal UKA usage
(defined as the percentage of knee arthroplasty practice comprised
by UKA) to minimise the rate of revision in a sample of 41 986 records
from the for National Joint Registry for England and Wales (NJR). UKA usage has a complex, non-linear relationship with the rate
of revision. Acceptable results are achieved with the use of 20%
or more. Optimal results are achieved with usage between 40% and
60%. Surgeons with the lowest usage (up to 5%) have the highest
rates of revision. With optimal usage, using the most commonly used
implant, five-year survival is 96% (95% confidence interval (CI)
94.9 to 96.0), compared with 90% (95% CI 88.4 to 91.6) with low
usage (5%) previously considered ideal. The rate of revision of UKA is highest with low usage, implying
the use of narrow, and perhaps inappropriate, indications. The widespread
use of broad indications, using appropriate implants, would give
patients the advantages of UKA, without the high rate of revision. Cite this article:
The August 2015 Knee Roundup360 looks at: Two days as good as three in TKA; Bilateral TKA: minimising the risks; Tranexamic acid in knee arthroplasty: everyone should be using it, but how?; Initial follow-up for knee arthroplasty?; Navigation finds its niche?; Another take on navigation?; Multimodal care for early knee osteoarthritis; ACL graft fixation methods under the spotlight
The June 2015 Knee Roundup360 looks at: Cruciate substituting
Subtotal or total meniscectomy in the medial or lateral compartment
of the knee results in a high risk of future osteoarthritis. Meniscal
allograft transplantation has been performed for over thirty years
with the scientifically plausible hypothesis that it functions in
a similar way to a native meniscus. It is thought that a meniscal
allograft transplant has a chondroprotective effect, reducing symptoms
and the long-term risk of osteoarthritis. However, this hypothesis has
never been tested in a high-quality study on human participants.
This study aims to address this shortfall by performing a pilot
randomised controlled trial within the context of a comprehensive
cohort study design. Patients will be randomised to receive either meniscal transplant
or a non-operative, personalised knee therapy program. MRIs will
be performed every four months for one year. The primary endpoint
is the mean change in cartilage volume in the weight-bearing area
of the knee at one year post intervention. Secondary outcome measures
include the mean change in cartilage thickness, T2 maps, patient-reported
outcome measures, health economics assessment and complications.Objectives
Methods
We studied whether the presence of lateral osteophytes
on plain radiographs was a predictor for the quality of cartilage
in the lateral compartment of patients with varus osteoarthritic
of the knee (Kellgren and Lawrence grade 2 to 3). The baseline MRIs of 344 patients from the Osteoarthritis Initiative
(OAI) who had varus osteoarthritis (OA) of the knee on hip-knee-ankle
radiographs were reviewed. Patients were categorised using the Osteoarthritis
Research Society International (OARSI) osteophyte grading system
into 174 patients with grade 0 (no osteophytes), 128 grade 1 (mild
osteophytes), 28 grade 2 (moderate osteophytes) and 14 grade 3 (severe
osteophytes) in the lateral compartment (tibia). All patients had
Kellgren and Lawrence grade 2 or 3 arthritis of the medial compartment.
The thickness and volume of the lateral cartilage and the percentage
of full-thickness cartilage defects in the lateral compartment was
analysed. There was no difference in the cartilage thickness or cartilage
volume between knees with osteophyte grades 0 to 3. The percentage
of full-thickness cartilage defects on the tibial side increased
from <
2% for grade 0 and 1 to 10% for grade 3. The lateral compartment cartilage volume and thickness is not
influenced by the presence of lateral compartment osteophytes in
patients with varus OA of the knee. Large lateral compartment osteophytes
(grade 3) increase the likelihood of full-thickness cartilage defects
in the lateral compartment. Cite this article:
The December 2014 Knee Roundup360 looks at: national guidance on arthroplasty thromboprophylaxis is effective; unicompartmental knee replacement has the edge in terms of short-term complications; stiff knees, timing and manipulation; neuropathic pain and total knee replacement; synovial fluid α-defensin and CRP: a new gold standard in joint infection diagnosis?; how to assess anterior knee pain?; where is the evidence? Five new implants under the spotlight; and a fresh look at ACL reconstruction
The June 2014 Knee Roundup360 looks at: acute repair preferable in hamstring ruptures; osteoarthritis a given in ACL injury, even with reconstruction?; chicken and egg: patellofemoral dysfunction and hip weakness; meniscal root tears as bad as we thought; outcomes in the meniscus; topical NSAIDs have a measurable effect on synovitis; nailing for tibial peri-prosthetic fracture.
The April 2014 Knee Roundup360 looks at: mobile compression as good as chemical thromboprophylaxis; patellar injury with MIS knee surgery; tibial plateau fracture results not as good as we thought; back and knee pain; metaphyseal sleeves may be the answer in revision knee replacement; oral tranexamic acid; gentamycin alone in antibiotic spacers; and whether the jury is still out on unloader braces.
The role of arthroscopy in the treatment of soft-tissue
injuries associated with proximal tibial fractures remains debatable.
Our hypothesis was that MRI over-diagnoses clinically relevant associated
soft-tissue injuries. This prospective study involved 50 consecutive
patients who underwent surgical treatment for a split-depression fracture
of the lateral tibial condyle (AO/OTA type B3.1). The mean age of
patients was 50 years (23 to 86) and 27 (54%) were female. All patients
had MRI and arthroscopy. Arthroscopy identified 12 tears of the
lateral meniscus, including eight bucket-handle tears that were
sutured and four that were resected, as well as six tears of the
medial meniscus, of which five were resected. Lateral meniscal injuries
were diagnosed on MRI in four of 12 patients, yielding an overall
sensitivity of 33% (95% confidence interval (CI) 11 to 65). Specificity
was 76% (95% CI 59 to 88), with nine tears diagnosed among 38 menisci
that did not contain a tear. MRI identified medial meniscal injuries
in four of six patients, yielding an overall sensitivity of 67%
(95% CI 24 to 94). Specificity was 66% (95% CI 50 to 79), with 15
tears diagnosed in 44 menisci that did not contain tears. MRI appears to offer only a marginal benefit as the specificity
and sensitivity for diagnosing meniscal injuries are poor in patients
with a fracture. There were fewer arthroscopically-confirmed associated
lesions than reported previously in MRI studies. Cite this article:
The April 2013 Knee Roundup360 looks at: graft tension and outcome; chondrocytes at the midterm; pre-operative deformity and failure; the designer effect; whether chondroitin sulphate really does work; whether ACL reconstruction is really required; analgesia after TKR; and degenerative meniscus.
The February 2013 Children’s orthopaedics Roundup360 looks at: the human genome; new RNA; cells, matrix and gene enhancement; the histology of x-rays; THR and VTE in the Danish population; potential therapeutic targets for GCT; optimising vancomycin elution from cement; and how much sleep is enough.
Patient-specific cutting guides (PSCGs) are designed
to improve the accuracy of alignment of total knee replacement (TKR).
We compared the accuracy of limb alignment and component positioning
after TKR performed using PSCGs or conventional instrumentation.
A total of 80 patients were randomised to undergo TKR with either of
the different forms of instrumentation, and radiological outcomes
and peri-operative factors such as operating time were assessed.
No significant difference was observed between the groups in terms
of tibiofemoral angle or femoral component alignment. Although the
tibial component in the PSCGs group was measurably closer to neutral
alignment than in the conventional group, the size of the difference
was very small (89.8° ( Cite this article:
The Oxford mobile-bearing unicompartmental knee
replacement (UKR) is an effective and safe treatment for osteoarthritis
of the medial compartment. The results in the lateral compartment
have been disappointing due to a high early rate of dislocation
of the bearing. A series using a newly designed domed tibial component
is reported. The first 50 consecutive domed lateral Oxford UKRs in 50 patients
with a mean follow-up of three years (2.0 to 4.3) were included.
Clinical scores were obtained prospectively and Kaplan-Meier survival
analysis was performed for different endpoints. Radiological variables
related to the position and alignment of the components were measured. One patient died and none was lost to follow-up. The cumulative
incidence of dislocation was 6.2% (95% confidence interval (CI)
2.0 to 17.9) at three years. Survival using revision for any reason
and aseptic revision was 94% (95% CI 82 to 98) and 96% (95% CI 85
to 99) at three years, respectively. Outcome scores, visual analogue
scale for pain and maximum knee flexion showed a significant improvement
(p <
0.001). The mean Oxford knee score was 43 ( Clinical results are excellent and short-term survival has improved
when compared with earlier series. The risk of dislocation remains
higher using a mobile-bearing UKR in the lateral compartment when
compared with the medial compartment. Patients should be informed
about this complication. To avoid dislocations, care must be taken
not to elevate the lateral joint line.