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The Bone & Joint Journal
Vol. 102-B, Issue 1 | Pages 72 - 81
1 Jan 2020
Downie S Lai FY Joss J Adamson D Jariwala AC

Aims

The early mortality in patients with hip fractures from bony metastases is unknown. The objectives of this study were to quantify 30- and 90-day mortality in patients with proximal femoral metastases, and to create a mortality prediction tool based on biomarkers associated with early death.

Methods

This was a retrospective cohort study of consecutive patients referred to the orthopaedic department at a UK trauma centre with a proximal femoral metastasis (PFM) over a seven-year period (2010 to 2016). The study group were compared to a matched control group of non-metastatic hip fractures. Minimum follow-up was one year.


The Journal of Bone & Joint Surgery British Volume
Vol. 45-B, Issue 1 | Pages 132 - 137
1 Feb 1963
Tyer HDD Sturrock WDS Callow FM

Retrosternal dislocation of the clavicle is an uncommon yet easily induced injury which may cause grave disability. Manipulation is rarely successful and usually open reduction with stabilisation of the joint is required. The literature on this subject is reviewed and an additional two cases are reported


The Journal of Bone & Joint Surgery British Volume
Vol. 43-B, Issue 4 | Pages 734 - 737
1 Nov 1961
Braddock GTF

1. The radiographic appearances are no guide to prognosis or treatment of peroneal spastic flat foot. 2. Only 10 per cent of peroneal spastic flat feet are likely to cause severe persistent disability. 3. Severe symptomatic tarsal arthritis is exceptional in this condition


Bone & Joint 360
Vol. 8, Issue 6 | Pages 26 - 29
1 Dec 2019


The Journal of Bone & Joint Surgery British Volume
Vol. 53-B, Issue 4 | Pages 688 - 695
1 Nov 1971
Warren G

1. Tarsal bone disintegration is a progressive disorder that affects a high proportion of leprosy patients. 2. Early detection and treatment by immobilisation permit healing with minimal deformity or disability. 3. Feet with advanced lesions can be similarly treated with a satisfactory outcome and amputation is not needed


The Journal of Bone & Joint Surgery British Volume
Vol. 50-B, Issue 2 | Pages 285 - 289
1 May 1968
Green JP Waugh W

1. Four cases of congenital lateral dislocation of the patella are described. 2. The significance of the associated flexion contracture is emphasised. 3. Early diagnosis and operative realignment of the extensor mechanism is considered to be important because it should avoid the secondary growth changes which can produce serious disability


Bone & Joint Research
Vol. 9, Issue 1 | Pages 1 - 14
1 Jan 2020
Stewart S Darwood A Masouros S Higgins C Ramasamy A

Bone is one of the most highly adaptive tissues in the body, possessing the capability to alter its morphology and function in response to stimuli in its surrounding environment. The ability of bone to sense and convert external mechanical stimuli into a biochemical response, which ultimately alters the phenotype and function of the cell, is described as mechanotransduction. This review aims to describe the fundamental physiology and biomechanisms that occur to induce osteogenic adaptation of a cell following application of a physical stimulus. Considerable developments have been made in recent years in our understanding of how cells orchestrate this complex interplay of processes, and have become the focus of research in osteogenesis. We will discuss current areas of preclinical and clinical research exploring the harnessing of mechanotransductive properties of cells and applying them therapeutically, both in the context of fracture healing and de novo bone formation in situations such as nonunion.

Cite this article: Bone Joint Res 2019;9(1):1–14.


The Journal of Bone & Joint Surgery British Volume
Vol. 36-B, Issue 4 | Pages 618 - 621
1 Nov 1954
Smith AM

Sprain of the pisiform triquetral joint is a definite clinical entity. It presents as a "tenosynovitis" of the flexor carpi ulnaris muscle from which it can be distinguished by the tests described. The disability in most cases is such that operation is justifiable. Fusion of the pisiform-triquetral joint is preferred to excision of the pisiform because it restores stability to the wrist with the least disturbance to related structures


The Bone & Joint Journal
Vol. 101-B, Issue 12 | Pages 1550 - 1556
1 Dec 2019
Mc Colgan R Dalton DM Cassar-Gheiti AJ Fox CM O’Sullivan ME

Aims

The aim of this study was to examine trends in the management of fractures of the distal radius in Ireland over a ten-year period, and to determine if there were any changes in response to the English Distal Radius Acute Fracture Fixation Trial (DRAFFT).

Patients and Methods

Data was grouped into annual intervals from 2008 to 2017. All adult inpatient episodes that involved emergency surgery for fractures of the distal radius were included


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 5 | Pages 646 - 651
1 Jul 2000
McKee MD Kim J Kebaish K Stephen DJG Kreder HJ Schemitsch EH

We reviewed 26 patients who had had internal fixation of an open intra-articular supracondylar fracture of the humerus. All operations were performed using a posterior approach, 13 with a triceps split and 13 with an olecranon osteotomy. The outcome was assessed by means of the Mayo Elbow score, the Disability of the Arm, Shoulder and Hand (DASH) score and the SF-36 Physical Function score. Patients with an olecranon osteotomy had less good results


The Journal of Bone & Joint Surgery British Volume
Vol. 60-B, Issue 4 | Pages 533 - 535
1 Nov 1978
Roper B Williams A King J

Adults with deformities of the lower limb due to spasticity may be considerably improved by operation, but thorough pre-operative assessment as an inpatient is essential in order to pinpoint the disability. The commonest deformity is equinovarus which often responds to simple operative procedures. The results of seventy-seven operative procedures in fifty patients are recorded. Correction once achieved is stable and the deformity does not recur


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 3 | Pages 352 - 355
1 Mar 2005
Wilson-MacDonald J Burt G Griffin D Glynn C

We have assessed whether an epidural steroid injection is effective in the treatment of symptoms due to compression of a nerve root in the lumbar spine by carrying out a prospective, randomised, controlled trial in which patients received either an epidural steroid injection or an intramuscular injection of local anaesthetic and steroid. We assessed a total of 93 patients according to the Oxford pain chart and the Oswestry disability index and followed up for a minimum of two years. All the patients had been categorised as potential candidates for surgery. There was a significant reduction in pain early on in those having an epidural steroid injection but no difference in the long term between the two groups. The rate of subsequent operation in the groups was similar


The Journal of Bone & Joint Surgery British Volume
Vol. 61-B, Issue 1 | Pages 90 - 93
1 Feb 1979
Noble J McQuillan W

Displaced fractures of the os calcis involving the subtalar joint frequently cause chronic disability due to subsequent osteoarthritis. Early posterior subtalar fusion may prevent this outcome. We have reviewed forty-seven fractures in forty-three patients at an average of seven years after operation. Over 90 per cent of patients had an excellent, good or satisfactory result


The Journal of Bone & Joint Surgery British Volume
Vol. 51-B, Issue 3 | Pages 464 - 468
1 Aug 1969
Colwill M

1. Three cases of osteomyelitis of a metatarsal sesamoid bone are described. 2. The diagnosis should be considered in patients with acute pain under the first metatarsophalangeal joint, particularly if the temperature is elevated. 3. Failure ofdiagnosis may lead to persistent disability until sinus formation and sequestration dictate operative intervention. 4. Early antibiotic therapy may lead to resolution of the infection


Bone & Joint 360
Vol. 8, Issue 1 | Pages 25 - 27
1 Feb 2019


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 4 | Pages 625 - 627
1 Jul 1990
Wootton Cross M Holt K

We report three cases of avulsion of the ischial tuberosity with marked chronic disability after delay in diagnosis and non-union of the fracture. All were treated by open reduction and internal fixation with return to full function, allowing in one case, athletic performances of Olympic standard. We also report one patient with an acute apophyseal avulsion treated by early reduction and internal fixation with restoration of full function


The Journal of Bone & Joint Surgery British Volume
Vol. 32-B, Issue 2 | Pages 148 - 160
1 May 1950
Osborne GV Fahrni WH

1. Experimental evidence is advanced to suggest that the effect of the McMurray displacement osteotomy in osteoarthritis of the hip is to diminish the load carried by the head of the femur, firstly by correction of deformity, and secondly by a "pelvic support" action. 2. A review of seventy-five cases has revealed certain important details in selection and operative management. The end-results indicate that the operation, when correctly performed, is successful in relieving pain and diminishing disability


The Journal of Bone & Joint Surgery British Volume
Vol. 76-B, Issue 6 | Pages 964 - 968
1 Nov 1994
Varley G Calvey J Hunter J Barton N Davis T

We have assessed the results of 34 simple excisions of the trapezium, with no additional soft-tissue procedures, in 30 patients. At a median follow-up of five years (2 to 22), 16 thumbs (47%) were completely painfree and a further 10 (29%) were slightly painful after use. Nineteen thumbs (56%) had no functional disability, but thumb-pinch strength was reduced by about 20%. No patient had painful degeneration at the scaphotrapezial pseudarthrosis


The Bone & Joint Journal
Vol. 101-B, Issue 6 | Pages 715 - 723
1 Jun 2019
Jayakumar P Teunis T Williams M Lamb SE Ring D Gwilym S

Aims

The purpose of this study was to identify factors associated with limitations in function, measured by patient-reported outcome measures (PROMs), six to nine months after a proximal humeral fracture, from a range of demographic, injury, psychological, and social variables measured within a week and two to four weeks after injury.

Patients and Methods

We enrolled 177 adult patients who sustained an isolated proximal humeral fracture into the study and invited them to complete PROMs at their initial outpatient visit within one week of injury, between two and four weeks, and between six to nine months after injury. There were 128 women and 49 men; the mean age was 66 years (sd 16; 18 to 95). In all, 173 patients completed the final assessment. Bivariate analysis was performed followed by multivariable regression analysis accounting for multicollinearity using partial R2, correlation matrices, and variable inflation factor.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 1 | Pages 57 - 61
1 Jan 2011
Naveed MA Kitson J Bunker TD

The combination of an irreparable tear of the rotator cuff and destructive arthritis of the shoulder joint may cause severe pain, disability and loss of independence in the aged. Standard anatomical shoulder replacements depend on a functioning rotator cuff, and hence may fail in the presence of tears in the cuff. Many designs of non-anatomical constrained or semi-constrained prostheses have been developed for cuff tear arthropathy, but have proved unsatisfactory and were abandoned. The DePuy Delta III reverse prosthesis, designed by Grammont, medialises and stabilises the centre of rotation of the shoulder joint and has shown early promise. This study evaluated the mid-term clinical and radiological results of this arthroplasty in a consecutive series of 50 shoulders in 43 patients with a painful pseudoparalysis due to an irreparable cuff tear and destructive arthritis, performed over a period of seven years by a single surgeon. A follow-up of 98% was achieved, with a mean duration of 39 months (8 to 81). The mean age of the patients at the time of surgery was 81 years (59 to 95). The female to male ratio was 5:1. During the seven years, six patients died of natural causes. The clinical outcome was assessed using the American Shoulder and Elbow score, the Oxford Shoulder Score and the Short-form 36 score. A radiological review was performed using the Sirveaux score for scapular notching. The mean American Shoulder and Elbow score was 19 (95% confidence interval (CI) 14 to 23) pre-operatively, and 65 (95% CI 48 to 82) (paired t-test, p < 0.001) at final follow-up. The mean Oxford score was 44 (95% CI 40 to 51) pre-operatively and 23 (95% CI 18 to 28) (paired t-test, p < 0.001) at final follow-up. The mean maximum elevation improved from 55° pre-operatively to 105° at final follow-up. There were seven complications during the whole series, although only four patients required further surgery