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The Journal of Bone & Joint Surgery British Volume
Vol. 53-B, Issue 3 | Pages 568 - 568
1 Aug 1971
Ellis J


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 6 | Pages 844 - 844
1 Jun 2009
Challis J


The Bone & Joint Journal
Vol. 96-B, Issue 9 | Pages 1258 - 1263
1 Sep 2014
Schuh R Panotopoulos J Puchner SE Willegger M M. Hobusch G Windhager R Funovics PT

Resection of a primary sarcoma of the diaphysis of a long bone creates a large defect. The biological options for reconstruction include the use of a vascularised and non-vascularised fibular autograft.

The purpose of the present study was to compare these methods of reconstruction.

Between 1985 and 2007, 53 patients (26 male and 27 female) underwent biological reconstruction of a diaphyseal defect after resection of a primary sarcoma. Their mean age was 20.7 years (3.6 to 62.4). Of these, 26 (49 %) had a vascularised and 27 (51 %) a non-vascularised fibular autograft. Either method could have been used for any patient in the study. The mean follow-up was 52 months (12 to 259). Oncological, surgical and functional outcome were evaluated. Kaplan–Meier analysis was performed for graft survival with major complication as the end point.

At final follow-up, eight patients had died of disease. Primary union was achieved in 40 patients (75%); 22 (42%) with a vascularised fibular autograft and 18 (34%) a non-vascularised (p = 0.167). A total of 32 patients (60%) required revision surgery. Kaplan–Meier analysis revealed a mean survival without complication of 36 months (0.06 to 107.3, sd 9) for the vascularised group and 88 months (0.33 to 163.9, sd 16) for the non-vascularised group (p = 0.035).

Both groups seem to be reliable biological methods of reconstructing a diaphyseal bone defect. Vascularised autografts require more revisions mainly due to problems with wound healing in distal sites of tumour, such as the foot.

Cite this article: Bone Joint J 2014;96-B:1258–63.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 3 | Pages 419 - 419
1 Mar 2006
Laurence M


The Journal of Bone & Joint Surgery British Volume
Vol. 85-B, Issue 2 | Pages 157 - 166
1 Mar 2003
Graham HK Selber P


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 1 | Pages 1 - 2
1 Jan 2001
Macnicol MF


The Journal of Bone & Joint Surgery British Volume
Vol. 80-B, Issue 2 | Pages 373 - 373
1 Mar 1998
Bingham J


The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 6 | Pages 984 - 985
1 Nov 1996
Quint U Vanhöfer U Harstrick A Müller RT

Local treatment with phenol is often used after intralesional excision of chondroblastomas and giant-cell tumours which involve bone near joints, and has been shown to reduce the rate of recurrence. The ideal concentration of phenol is uncertain, but may be important because of the high rate of absorption and toxicity. We have studied the effectiveness of different concentrations on standard sarcoma cell lines.

Our results suggest that a 5% solution of phenol is effective against dispersed single cells, and that higher concentrations give no significant advantage, but create problems due to lack of homogeneous mixing, temperature and safety.


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 5 | Pages 778 - 778
1 Jul 2002
Laurence M


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 8 | Pages 1211 - 1211
1 Nov 2001
Laurence M


The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 3 | Pages 513 - 514
1 May 1996
Grahame R


The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 2 | Pages 340 - 340
1 Mar 1996
Laurence M


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 3 | Pages 490 - 493
1 May 1990
Carter Eastwood D Grimer R Sneath R

We reviewed 34 hindquarter amputations performed for malignant tumours around the hip from 1971 to 1988, classifying them as palliative or curative according to the resection margins or the presence of disseminated disease at the time of surgery. There were three peri-operative deaths, 12 palliative and 19 curative procedures. Ten patients died of disseminated disease within a year of surgery, eight of whom had had a palliative operation. Three patients died between one and five years after palliative surgery. One died of unrelated disease at nine years. Seventeen patients are disease free an average of 31 months from surgery, 16 after curative procedures. The median survival after palliative amputations was six months and the 5-year survival rate for curative cases was 83%.


The Journal of Bone & Joint Surgery British Volume
Vol. 53-B, Issue 4 | Pages 775 - 775
1 Nov 1971
James JIP


The Journal of Bone & Joint Surgery British Volume
Vol. 80-B, Issue 3 | Pages 561 - 561
1 May 1998
Atkins RM


The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 3 | Pages 501 - 506
1 May 1996
Rydholm FA


The Journal of Bone & Joint Surgery British Volume
Vol. 52-B, Issue 3 | Pages 588 - 589
1 Aug 1970
Freeman MAR


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 12 | Pages 1719 - 1719
1 Dec 2010
Klenerman L


The Journal of Bone & Joint Surgery British Volume
Vol. 73-B, Issue 3 | Pages 498 - 500
1 May 1991
Stoker D Cobb J Pringle J

Needle biopsies, performed on 208 consecutive patients and interpreted at the London Bone Tumour Service over a two-year period, were reviewed. A correct diagnosis was reached in 97% (133 out of 137) using this technique alone. Needle biopsy is safe and accurate when undertaken in consultation within a bone tumour service; it offers considerable advantages to both patient and surgeon over conventional open biopsy.


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 2 | Pages 322 - 323
1 Mar 1990
McGoey B Deitel M Saplys R Kliman M