1. Previous reports of calcareous deposits about the metacarpo-phalangeal joints are reviewed, and four further cases are described. 2. The clinical features are described, with reference to the possibility of erroneous diagnosis. 3. Conservative treatment is recommended.
1. Experience in the treatment of tuberculous disease of the spine, hip and knee by combined constitutional, antibiotic and operative measures is described. 2. In patients with tuberculosis of the spine, especially in the thoracic region and when perispinal abscess formation is a prominent feature, the treatment helps to ensure stable ankylosis in the type of case in which it otherwise might not occur. 3. In children with tuberculosis of the hip and in adults and children with tuberculosis of the knee it is usually possible to save the joint and to restore function, provided the joint has not been destroyed before treatment is begun.
One hundred normal fingers were dissected and arthrographs obtained by injection of a chromopaquegelatin mixture, allowing comparison between the radiographic and macroscopic configuration of the synovial capsule. Synovial recesses protruding from each side of every metacarpo-phalangeal joint were found in relation to the collateral ligaments and corresponding exactly with the site of radiological erosions. A group of bursae lying on the superficial aspect of collateral ligaments were also demonstrated. A rudimentary infra-articular meniscus was found. The results of examination of the insertions of the interossei showed differences from traditional descriptions. The cause of rheumatoid deformity was suggested to be the rheumatoid process arising in the lateral recesses and lateral bursae, weakening the collateral ligaments, which give way in the directions of the deforming forces. These are derived from the long flexor tendons, which were shown to exert an ulnar and volar strain on the metacarpo-phalangeal joint of every finger during grip.
1. A method of finger dissection is described which provides a new approach to the anatomical study of structures in close relation to joints. 2. The volar part of the capsule of the finger joints is described, the attachment to the bones being particularly emphasised together with its form which is like that of a meniscus. 3. A gap between bone and tendon sheath is described. 4. Theoretical and clinical aspects of the local anatomy are discussed.
1. The range of variation in full extension at the interphalangeal and metacarpo-phalangeal joints of the thumbs of 133 male and 100 female Europeans, and of 31 male Indians and 30 male Africans, has been investigated. 2. There is considerable variation between individuals in the maximum extension of both joints of the right and left thumbs in all groups studied. 3. The distribution for each joint in both thumbs in all groups is fairly symmetrical. 4. There is a high correlation between the right and left thumbs for both joints in all groups 5. The mean angle of extension at the right and left metacarpo-phalangeal joints in all groups is similar. Female Europeans, however, show a significantly greater mean angle than male Europeans. 6. The mean interphalangeal angle of extension in male Europeans is significantly greater than that in female Europeans and the mean in the Indian and African groups is significantly greater than in the male European group. 7. There is slight negative correlation between the metacarpo-phalangeal angle and interphalangeal angle in each thumb in the European groups. 8. Many subjects in all groups can increase extension at the metacarpo-phalangeal joint after flexing the carpo-metacarpal joint. Marked hyperextension (over 40°) is more frequent in the left than in the right thumb, in females than in males, and in male Indians than in male Europeans and Africans. 9. Maximum extension at the interphalangeal joints is not related to the presence of a sesamoid bone in the anterior part of the capsule of the joint. 10. The surfaces of the metacarpo-phalangeal joints vary considerably in shape. Those which are flat form about 10 per cent. of the sample and do not show hyperextension. 11. The factors influencing the amount of extension at the interphalangeal joint is the degree of laxity of the anterior capsule. The problem at the metacarpo-phalangeal joint is more complex; both the capsule and the shape of the joint surfaces play important roles.
1. Four joints of three young haemophiliacs who died in traffic accidents have been examined. 2. All patients had received prompt specific treatment for intra-articular and other haemorrhages. 3. Major macroscopic and histological changes were seen in the joints, but these changes were not quite so severe as those described before the days of specific treatment. 4. The possibilities of preventing articular changes and of minimising the effect of blood in the joints are discussed.
1. Two cases of osteochondritis dissecans affecting several joints are described. 2. There is no evidence that injury, congenital anomaly or constitutional disturbance played any part in the etiology of either case.
1. Synovial fluid acts mechanically by forming a convergent lubricant film between the fixed and the moving joint surfaces. This term and the underlying theory are explained. 2. The fatty pads assist lubrication by reducing the "mechanical curvature" in joints with more highly curved surfaces. 3. The intra-articular discs and menisci increase the "mechanical curvature" in joints with surfaces of small curvature. 4. Sesamoid bones exert a "bow-string pressure" upon the bones with which they articulate. This is a corollary from the theory of lubrication.
1. This paper describes the macroscopic and microscopic changes that are seen in posterior intervertebral joints after anterior vertebral fusion. 2. We now have a reasonably clear view of the types of change seen under these circumstances. The type varies from case to case and in different parts of the same specimen. So far we have no clear idea of the sequence or the pattern that leads from the normal to complete fibrosis or osseous ankylosis. 3. Further experimental work is needed in order to build up a clear concept of the sequence of events and of their relative importance. To do this it will be necessary to immobilise joints for longer than before.
Aims. Staphylococcus aureus is a major cause of septic arthritis, and in vitro studies suggest α haemolysin (Hla) is responsible for chondrocyte death. We used an in vivo murine joint model to compare inoculation with wild type S. aureus 8325-4 with a Hla-deficient strain DU1090 on chondrocyte viability, tissue histology, and joint biomechanics. The aim was to compare the actions of S. aureus Hla alone with those of the animal’s immune response to infection. Methods. Adult male C57Bl/6 mice (n = 75) were randomized into three groups to receive 1.0 to 1.4 × 10. 7. colony-forming units (CFUs)/ml of 8325-4, DU1090, or saline into the right stifle joint. Chondrocyte death was assessed by confocal microscopy. Histological changes to inoculated joints were graded for inflammatory responses along with gait, weight changes, and limb swelling. Results. Chondrocyte death was greater with 8325-4 (96.2% (SD 5.5%); p < 0.001) than DU1090 (28.9% (SD 16.0%); p = 0.009) and both were higher than controls (3.8% (SD 1.2%)). Histology revealed cartilage/bone damage with 8325-4 or DU1090 compared to controls (p = 0.010). Both infected groups lost weight (p = 0.006 for both) and experienced limb swelling (p = 0.043 and p = 0.018, respectively).
We examined 204 children (137 boys and 67 girls) aged 12 years and under with septic arthritis. Their mean age was 31.1 months (1 to 144; SD 41.6). The most common joints affected were the knees and shoulders.
