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The Bone & Joint Journal
Vol. 106-B, Issue 3 | Pages 256 - 261
1 Mar 2024
Goodall R Borsky K Harrison CJ Welck M Malhotra K Rodrigues JN

Aims. The Manchester-Oxford Foot Questionnaire (MOxFQ) is an anatomically specific patient-reported outcome measure (PROM) currently used to assess a wide variety of foot and ankle pathology. It consists of 16 items across three subscales measuring distinct but related traits: walking/standing ability, pain, and social interaction. It is the most used foot and ankle PROM in the UK. Initial MOxFQ validation involved analysis of 100 individuals undergoing hallux valgus surgery. This project aimed to establish whether an individual’s response to the MOxFQ varies with anatomical region of disease (measurement invariance), and to explore structural validity of the factor structure (subscale items) of the MOxFQ. Methods. This was a single-centre, prospective cohort study involving 6,637 patients (mean age 52 years (SD 17.79)) presenting with a wide range of foot and ankle pathologies between January 2013 and December 2021. To assess whether the MOxFQ responses vary by anatomical region of foot and ankle disease, we performed multigroup confirmatory factor analysis. To assess the structural validity of the subscale items, exploratory and confirmatory factor analyses were performed. Results. Measurement invariance by pathology was confirmed, suggesting the same model can be used across all foot and ankle anatomical regions. Exploratory factor analysis demonstrated a two- to three-factor model, and suggested that item 13 (inability to carry out work/everyday activities) and item 14 (inability to undertake social/recreational activities) loaded more positively onto the “walking/standing” subscale than their original “social interaction” subscale. Conclusion. This large cohort study supports the current widespread use of the MOxFQ across a broad range of foot and ankle pathologies. Our analyses found indications that could support alterations to the original factor structure (items 13 and 14 might be moved from the “social interaction” to the “walking/standing” subscale). However, this requires further work to confirm. Cite this article: Bone Joint J 2024;106-B(3):256–261


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 2 | Pages 309 - 309
1 Mar 2002
Walsh HPJ


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 6 | Pages 934 - 934
1 Aug 2001
Angel J


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 1 | Pages 154 - 154
1 Jan 2001
Klenerman L


The Journal of Bone & Joint Surgery British Volume
Vol. 81-B, Issue 2 | Pages 370 - 370
1 Mar 1999
CONNOLLY JF


The Journal of Bone & Joint Surgery British Volume
Vol. 81-B, Issue 1 | Pages 178 - 178
1 Jan 1999
CARR JB


The Journal of Bone & Joint Surgery British Volume
Vol. 80-B, Issue 1 | Pages 11 - 12
1 Jan 1998
Klenerman L


The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 4 | Pages 685 - 685
1 Jul 1996
Halpin DS


The Journal of Bone & Joint Surgery British Volume
Vol. 77-B, Issue 4 | Pages 659 - 660
1 Jul 1995
Tibrewal S Iossifidis A


The Journal of Bone & Joint Surgery British Volume
Vol. 49-B, Issue 3 | Pages 562 - 562
1 Aug 1967
Williams AT


The Journal of Bone & Joint Surgery British Volume
Vol. 47-B, Issue 4 | Pages 609 - 611
1 Nov 1965
Bonnin JG


The Journal of Bone & Joint Surgery British Volume
Vol. 32-B, Issue 1 | Pages 68 - 69
1 Feb 1950
McMurray TP


The Journal of Bone & Joint Surgery British Volume
Vol. 30-B, Issue 4 | Pages 619 - 621
1 Nov 1948
Gallie WE


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 8 | Pages 1208 - 1208
1 Nov 2000
Klenerman L


The Bone & Joint Journal
Vol. 105-B, Issue 8 | Pages 895 - 904
1 Aug 2023
Smith TO Dainty J Loveday DT Toms A Goldberg AJ Watts L Pennington MW Dawson J van der Meulen J MacGregor AJ

Aims. The aim of this study was to capture 12-month outcomes from a representative multicentre cohort of patients undergoing total ankle arthroplasty (TAA), describe the pattern of patient-reported outcome measures (PROMs) at 12 months, and identify predictors of these outcome measures. Methods. Patients listed for a primary TAA at 19 NHS hospitals between February 2016 and October 2017 were eligible. PROMs data were collected preoperatively and at six and 12 months including: Manchester-Oxford Foot and Ankle Questionnaire (MOXFQ (foot and ankle)) and the EuroQol five-dimension five-level questionnaire (EQ-5D-5L). Radiological pre- and postoperative data included Kellgren-Lawrence score and implant position measurement. This was supplemented by data from the National Joint Registry through record linkage to determine: American Society of Anesthesiologists (ASA) grade at index procedure; indication for surgery, index ankle previous fracture; tibial hind foot alignment; additional surgery at the time of TAA; and implant type. Multivariate regression models assessed outcomes, and the relationship between MOXFQ and EQ-5D-5L outcomes, with patient characteristics. Results. Data from 238 patients were analyzed. There were significant improvements in MOXFQ and EQ-5D-5L among people who underwent TAA at six- and 12-month assessments compared with preoperative scores (p < 0.001). Most improvement occurred between preoperative and six months, with little further improvement at 12 months. A greater improvement in MOXFQ outcome postoperatively was associated with older age and more advanced radiological signs of ankle osteoarthritis at baseline. Conclusion. TAA significantly benefits patients with end-stage ankle disease. The lack of substantial further overall change between six and 12 months suggests that capturing PROMs at six months is sufficient to assess the success of the procedure. Older patients and those with advanced radiological disease had the greater gains. These outcome predictors can be used to counsel younger patients and those with earlier ankle disease on the expectations of TAA. Cite this article: Bone Joint J 2023;105-B(8):895–904


The Journal of Bone & Joint Surgery British Volume
Vol. 79-B, Issue 4 | Pages 700 - 701
1 Jul 1997
Klenerman L


The Journal of Bone & Joint Surgery British Volume
Vol. 79-B, Issue 3 | Pages 511 - 512
1 May 1997
HELAL B


The Journal of Bone & Joint Surgery British Volume
Vol. 77-B, Issue 3 | Pages 510 - 510
1 May 1995
Van der Rijt A Evans G


The Journal of Bone & Joint Surgery British Volume
Vol. 68-B, Issue 2 | Pages 266 - 267
1 Mar 1986
Baciu C

We report the results of a simple technique of ankle arthrodesis which is, however, indicated only when the foot can be reduced manually to a functional position. A special milling-cutter with an expulsion piston is used to obtain a cylindrical bone graft which is reintroduced having been reversed from left to right and rotated through 90 degrees. The operation is simple and very rapid. It has been performed on 72 patients, 62 of whom have been followed up for an average of six years. Fifty-seven were painless with bony fusion in a functional position; one was solid and painless but in valgus. In only four patients were the results unsatisfactory.


The Journal of Bone & Joint Surgery British Volume
Vol. 67-B, Issue 5 | Pages 689 - 690
1 Nov 1985
Hamblen D