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The Bone & Joint Journal

Oncology
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The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 7 | Pages 1006 - 1010
1 Sep 2000
Rödl RW Ozaki T Hoffmann C Böttner F Lindner N Winkelmann W

We assessed the results of 17 limb-salvage procedures using osteoarticular allografts after wide resection of high-grade malignant bone tumours. All patients received chemotherapy. At the five-year follow-up, three patients had died from metastases. The allografts survived for five years in only seven patients all of whom had good function, ranging from 73% to 90% of normal. The allografts were removed because of fracture in seven patients and infection in one, and in all of these a second limb-salvage procedure was undertaken.

With such a low rate of survival of osteoarticular allografts, we believe that their use in the management of high-grade malignant bone tumours should, at best, be considered a temporary solution.