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The Bone & Joint Journal
Vol. 101-B, Issue 10 | Pages 1238 - 1247
1 Oct 2019
Soreide E Denbeigh JM Lewallen EA Thaler R Xu W Berglund L Yao JJ Martinez A Nordsletten L van Wijnen AJ Kakar S

Aims

Options for the treatment of intra-articular ligament injuries are limited, and insufficient ligament reconstruction can cause painful joint instability, loss of function, and progressive development of degenerative arthritis. This study aimed to assess the capability of a biologically enhanced matrix material for ligament reconstruction to withstand tensile forces within the joint and enhance ligament regeneration needed to regain joint function.

Materials and Methods

A total of 18 New Zealand rabbits underwent bilateral anterior cruciate ligament reconstruction by autograft, FiberTape, or FiberTape-augmented autograft. Primary outcomes were biomechanical assessment (n = 17), microCT (µCT) assessment (n = 12), histological evaluation (n = 12), and quantitative polymerase chain reaction (qPCR) analysis (n = 6).


The Bone & Joint Journal
Vol. 98-B, Issue 11 | Pages 1479 - 1488
1 Nov 2016
Kalson NS Borthwick LA Mann DA Deehan DJ Lewis P Mann C Mont MA Morgan-Jones R Oussedik S Williams FMK Toms A Argenson JN Bellemans J Bhave A Furnes O Gollwitzer H Haddad FS Hofmann S Krenn V

Aims

The aim of this consensus was to develop a definition of post-operative fibrosis of the knee.

Patients and Methods

An international panel of experts took part in a formal consensus process composed of a discussion phase and three Delphi rounds.