1. Seven cases of massive osteoarticular transplant for conditions affecting major joints are described. In one case the whole femur was replaced.

2. The transplants were well accepted, though there was a varying degree of absorption of bone and necrosis of articular cartilage.

3. The functional results were very satisfactory, and movements of joints were well preserved. 4. In these cases recurrence of the original disease was not seen.

5. Such operations are still in an experimental stage, but they are likely to have a permanent place in treatment in certain carefully selected cases.