1. Four joints of three young haemophiliacs who died in traffic accidents have been examined. 2. All patients had received prompt specific treatment for intra-articular and other haemorrhages. 3. Major macroscopic and histological changes were seen in the joints, but these changes were not quite so severe as those described before the days of specific treatment. 4. The possibilities of preventing articular changes and of minimising the effect of blood in the joints are discussed.
1. The behaviour of various types of cortical bone graft has been studied in rabbits by histological and injection techniques. 2. The results suggest that penetration of the graft by blood vessels plays an important part in the incorporation of autogenous and homogenous grafts. 3. Autogenous and homogenous grafts are both incorporated–the latter more slowly than the former–but heterogenous grafts are rejected. The reasons for this rejection are discussed.
