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The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 3 | Pages 396 - 399
1 Mar 2006
Leichtle CI Leichtle UG Gärtner V Schimmel H Hartmann JT Rudert M

A giant cell tumour is a primary lesion of bone of intermediate severity. Its histogenesis is unclear. In a few cases pulmonary metastases have been described. Multiple skeletal metastases in the absence of sarcomatous change have been observed.

We present a case report of a 25-year-old woman with a recurrent giant cell tumour of the distal fibula. After a second recurrence and six years after the initial diagnosis, she rapidly developed multiple bony metastases. The outcome was fatal.