Aims

The objective of this study was to present the outcomes of rotational acetabular osteotomy (RAO) over a 30-year period for osteoarthritis (OA) secondary to dysplasia of the hip in pre- or early-stage OA.

Satisfactory intermediate and long-term results of rotational acetabular osteotomy (RAO) for the treatment of early osteoarthritis secondary to developmental dysplasia of the hip have been reported. The purpose of this study is to examine the 30-year results of RAO.

Between 1987 and 1994, we treated 49 patients (55 hips) with RAO for diagnosis of pre- OA or early-stage OA. Of those patients, 35 patients (43 hips) were available at a minimum of 28 years. The follow-up rate was 78.2% and the mean follow-up was 30.5 years. The mean age at the time of surgery was 34 years. Clinical evaluation was performed with the Merle d'Aubigne and Postel rating scale, and radiographic analyses included measurements of the center-edge angle, acetabular roof angle, and head lateralization index on preoperative, postoperative AP radiographs of the pelvis. Postoperative joint congruency was classified into four grades. The radiographic evidence of progression of OA was defined as the minimum joint space less than 2.5mm.

The mean preoperative clinical score was 14.0, which improved to a mean of 15.3 at the time of the latest follow-up. The mean center-edge angle improved from 0.6° preoperatively to 34° postoperatively, the mean acetabular roof angle improved from 28.4°preoperatively to 1.0°postoperatively, the mean head lateralization index improved from 0.642 preoperatively to 0.59 postoperatively. Postoperative joint congruency was excellent in 11 hips, good in 29 hips, and fair in 3 hips. Nineteen patients (20 hips) had radiographic OA progression, and 10 patients (11 hips) were converted to THA. Kaplan-Meier survivorship analysis, with radiographic OA progression as the end point, predicted survival of 75.6% at 20 years and 48.8% at 30 years, and with THA conversion as the end point, 90.2% at 20 years and 71.2% at 30 years.

The RAO is an effective surgical procedure for symptomatic dysplastic hips of pre- and early-stage OA and could change the natural history of the dysplastic hip.

Aims

Rotational acetabular osteotomy (RAO) has been reported to be effective in improving symptoms and preventing osteoarthritis (OA) progression in patients with mild to severe develomental dysplasia of the hip (DDH). However, some patients develop secondary OA even when the preoperative joint space is normal; determining who will progress to OA is difficult. We evaluated whether the preoperative cartilage condition may predict OA progression following surgery using T2 mapping MRI.

Aims

The aim of this study was to report the long-term results of rotational acetabular osteotomy (RAO) for symptomatic hip dysplasia in patients aged younger than 21 years at the time of surgery.

Adolescent and young adult patients with a history of DDH and residual hip dysplasia tend to have an early presentation of symptoms. In these patients, a severe acetabular dysplasia, aspheric femoral head and/or high greater trochanter are often observed. We evaluated the long-term results of rotational acetabular osteotomy (RAO) for symptomatic hip dysplasia in patients younger than 21 years.

We performed 492 RAOs for hip dysplasia from 1987 to 2017. In these cases, patients younger than 21 years at the time of surgery were 40 patients (46 hips). We evaluated 34 patients (40 hips, follow-up rate; 85%) retrospectively. There were 32 females and two males; their mean age at the time of surgery was 17.8 years (12–21). The mean follow-up period was 16.8 years (1–30). In eight hips, isolated RAO was not adequate to correct instability and/or congruency. For these hips, four varus femoral osteotomies, two valgus femoral osteotomies and two greater trochanter displacement were combined with RAO.

The mean clinical score (JOA) was improved from 80 to 90 significantly at the final follow-up. The mean CE angle was improved from −3.4 (−35–10) degrees to 27 (8–42) degrees, acetabular roof angle from 30 (15–60) degrees to 6.7 (−3–30) degrees, head lateralization index from 0.665 (0.5–1.0) to 0.614 (0.429–0.7) postoperatively. Radiographic OA progression was observed in four hips, but no hip was converted to THA.

The RAO is an effective technique for surgical correction of a relatively severe dysplastic hip in adolescent and young adults.

The transtrochanteric anterior rotational osteotomy (TRO) was developed by Sugioka as a joint-preserving procedure which prevents further deformity by transposing the necrotic area from a site of primary weight-bearing to a secondary area. We performed this procedure for children and young adults with various hip disorders.

Between 1994 and 2015 we performed TROs on 12 joints in 12 patients with SCFE (4), pigmented villonodular synovitis (2), septic arthritis (1), FAI (1), hip dysplasia (1), femoral neck fracture (2) and postoperative RAO (1). The mean age at the time of surgery was 21 years (10–43) and the mean follow-up period was 8 years (1–22). The rotational directions of the femoral head were anterior (5) and posterior (7). Clinical assessment was undertaken using the system of Merle d'Aubigné and Postel, grading pain, mobility and walking ability with scores from 0 to 6. Radiographically bone regeneration and OA progression were estimated.

The mean clinical score improved from 9.0 to 14.4 at final follow-up. Spur formation of femoral head was observed in 7 patients (58%). OA progression was in two patients (17%) and one patient was converted to THA 22 years after surgery. All cases with osteonecrosis in SCFE and femoral neck fracture showed remarkable bone regeneration.

The TRO is a reliable joint-preserving procedure for various hip disorders in children and young adults.

Aims

Our aim was to evaluate the radiographic characteristics of patients undergoing total hip arthroplasty (THA) for the potential of posterior bony impingement using CT simulations.

Background

The clinical results of total hip arthroplasty (THA) with a cementless prosthesis have been constantly improving due to progress in the area of stem design and surface finish. However, majority of stems are well-fixed with canal filling or diaphyseal fit, and cortical hypertrophy or metaphyseal bone atrophy has been often observed. Cementless Spotorno stem (CLS stem; Zimmer, Warsaw, USA) is a double-tapered rectangular straight stem. The purpose of this study is to investigate the mean 13 years' results of CLS stem and to evaluate the press-fit stability of CLS stem.

Introduction

Clione Anchored Replacement Prosthesis (CARP-H system) is a novel femoral implant for cementless fixation at the metaphysis of the proximal femur and preservation of cancellous bone of the femoral diaphysis is expected (Fig.1). We developed CARP-H system and started to use the prosthesis after the approval by Pharmaceuticals and Medical Devices Agency in 2012. This study examines the efficacy and short-term outcome of CARP-H system in a series of patients undergoing total hip arthroplasty (THA) or bipolar hemi-arthroplasty (BHA).

In Japan, osteoarthritis (OA) of the hip secondary to acetabular dysplasia is very common, and there are few data concerning the pathogeneses and incidence of femoroacetabular impingement (FAI). We have attempted to clarify the radiological prevalence of painful FAI in a cohort of Japanese patients and to investigate the radiological findings. We identified 176 symptomatic patients (202 hips) with Tönnis grade 0 or 1 osteoarthritis, whom we prospectively studied between August 2011 and July 2012. There were 61 men (65 hips) and 115 women (137 hips) with a mean age of 51.8 years (11 to 83). Radiological analyses included the α-angle, centre–edge angle, cross-over sign, pistol grip deformity and femoral head neck ratio. Of the 202 hips, 79 (39.1%) had acetabular dysplasia, while 80 hips (39.6%) had no known aetiology. We found evidence of FAI in 60 hips (29.7%). Radiological FAI findings associated with cam deformity were the most common. There was a significant relationship between the pistol grip deformity and both the α-angle (p < 0.001) and femoral head–neck ratio (p = 0.024). Radiological evidence of symptomatic FAI was not uncommon in these Japanese patients.

Cite this article: Bone Joint J 2013;96-B:172–6.

Introduction

Since 2005, we have performed implantation of bone marrow-derived mononuclear cells for osteonecrosis of the femoral head in order to improve vascularization and bone repair. This study focused on early bone repair of osteonecrosis of the femoral head after transplantation of bone marrow-derived mononuclear cells (BMMNC).

Background: A retroverted acetabulum has been hypothesized as a cause of osteoarthritis. This study was performed to evaluate whether radiographical cross-over sign influence the painful femoro-acetabular impingement or the radiographical progression of osteoarhritis after rotational acetabular osteotomy (RAO) for dysplastic hip.

Methods: Between 1987 and 1999, 104 patients (115 hips) who had pre- or early stage osteoarthritis of the hip due to dysplasia underwent a RAO. There were 99 women and five men; their mean age at the time of surgery was 34.7 years. The mean follow-up period was 13 years. Clinical follow-up was performed with use of the system of Merle d’Aubigne and the impingement sign was evaluated. Radiographical analyses included measurements of the center-edge angle, acetabular roof angle, head lateralization index, joint congruency, cross-over sign, posterior wall sign, acetabular index of depth to width, pistol grip deformity and femoral head-femoral neck ratio.

Results: The mean clinical score improved significantly from 14.6 preoperatively to 17.0 at follow-up. The impingement sign at the follow-up was observed in 14 hips (12.2%). The center-edge angle improved significantly from mean −0.6 degrees to a postoperative mean of 34 degrees. The acetabular roof angle improved from 30 degrees to 2.2 degrees, and head lateralization index from 0.64 to 0.60. The cross-over sign was observed in 8 hips (7.0%) preoperatively and in 49 hips (42.6%) postoperatively. The posterior wall sign was observed in 70 hips (60.9%) preoperatively and observed in 73 hips (63.5%) postoperatively. The mean preoperative acetabular index of depth to width was 35.5% and the mean preoperative femoral head to femoral neck ratio was 1.49. The pistol grip deformity was observed in only 4 hips (3.5%) preoperatively. The impingement sign after the RAO was positive significantly in the postoperative cross-over sign positive hips (p=0.0074). Radiographical progression of osteoarthritis was observed in 11 hips (cross over sign positive; 7 hips, cross over sign negative; 4 hips). The Kaplan-Meier survivorship analysis predicted a survival rate of 84.6 % at 15 years. The only factors significantly associated with radiographic signs of progression of osteoarthritis after RAO were fair (rather than excellent and good) postoperative joint congruency (p< 0.0001) and age at surgery (p=0.0042). Presence of postoperative cross-over sign had no effect on the outcome (p=0.2073).

Conclusions: Although there was no significant radiographical progression of osteoarthritis despite a significant retroversion in most cases, the goal of RAO should be a correct alignment of the acetabulum including a correct version with a negative cross-over sign.

We used interconnected porous calcium hydroxyapatite ceramic to bridge a rabbit ulnar defect. Two weeks after inducing the defect we percutaneously injected rabbit bone marrow-derived mesenchymal stromal cells labelled with ferumoxide. The contribution of an external magnetic targeting system to attract these cells into the ceramic and their effect on subsequent bone formation were evaluated.

This technique significantly facilitated the infiltration of ferumoxide-labelled cells into ceramic and significantly contributed to the enhancement of bone formation even in the chronic phase. As such, it is potentially of clinical use to treat fractures, bone defects, delayed union and nonunion.

We have investigated the effectiveness of the transplantation of bone-marrow-derived mononuclear cells (BMMNCs) with interconnected porous calcium hydroxyapatite (IP-CHA) on early bone repair for osteonecrosis of the femoral head. We studied 22 patients (30 hips) who had osteonecrosis with a minimum follow-up of one year after implantation of BMMNCs. The mean age at surgery was 41 years (18 to 64) and the mean period of follow-up was 29 months (19 to 48). In a control group, cell-free IP-CHA was implanted into a further eight patients (9 hips) with osteonecrosis of the femoral head and the outcomes were compared.

A reduction in the size of the osteonecrotic lesion was observed subsequent to hypertrophy of the bone in the transition zone in the BMMNC group. In three patients in the treatment group progression to extensive collapse was detected. In the control group subtle bone hypertrophy was observed, but severe collapse of the femoral head occurred in six of eight hips.

In this limited study the implantation of BMMNCs and IP-CHA appears to confer benefit in the repair of osteonecrosis and in the prevention of collapse.

Introduction. Dysplasia of the hip is the commonest cause of secondary osteoarthritis. One treatment is periacetabular osteotomy such as rotational acetabular osteotomy(RAO). These procedures have generally produced satisfactory mid- and long-term results, but unfavorable results have been reported in a few cases. We evaluated the 10-year results to determine the factors of prognostic importance.

Methods. We studied 91 patients (100 hips) at prearthritis or early stage. The mean age at surgery was 36 years (13 – 58) and mean follow-up period was 11 years (8–16). 81 were women (89 hips) and 10 were men (11 hips). Clinical follow-up was done using the system of Merle d’Aubigne. Radiologically, CE angle, AC angle and head lateralization index (HLI) were measured prior to surgery, 3 months postoperatively and at follow-up. Postoperative joint congruencies were classified into four grades.

Results. The mean clinical score significantly increased from 14 to 17 and only in 4 cases the mean score decreased. CE angle, AC angle, and HLI significantly improved after surgery. Progression of osteoarthritis was radiologically observed at follow-up in 7 hips. Kaplan-Meier survivorship analysis predicted the rate of prevention of osteoarthritic progression at 10 years as 93%. Parametric survivorship analysis using the Cox hazards model indicated that postoperative joint congruency is a risk factor for progression of osteoarthritis.

Discussion/Conclusion. Our findings have suggested that RAO is valuable in preventing osteoarthritic progression for at least 10 years. If risk factors can be reduced, a longer operative effect may be expected.

Acetabular dysplasia was produced in 24 immature white rabbits. A rotational acetabular osteotomy was then carried out and radiological and histological studies of the articular cartilage were made.

In the hips which did not undergo osteotomy, radiographs at 26 weeks showed that residual subluxation remained and arthritic changes such as narrowing of the joint space or dislocation were still seen. However, in the operated group there was a remarkable increase in cover, but arthritic changes were not observed. After 24 weeks, the Mankin grading score in the operated group was significantly lower than that in the non-operated group. The latter hips showed an irregular surface of the cartilage, exfoliation and proliferation of synovial tissue. In those undergoing osteotomy, primary cloning of chondrocytes or hypercellularity was seen and at 24 weeks after operation and metaplasia of the cartilage in the fibrous tissue was observed in the boundary between the medial area of the acetabulum and the acetabular fossa.

We have studied whether the state of the articular cartilage at the time of rotational acetabular osteotomy for dysplasia of the hip affects the outcome 2 to 5.5 years after surgery. Arthroscopy in 57 patients (59 joints) at the time of the operation showed grade-0 changes in seven, grade-1 in nine, grade-2 in 17, grade-3 in 14 and grade-4 in 12 joints, according to the classification of Outerbridge. There was radiological evidence of the progression of arthritis in four joints which were classified at arthroscopy as grade 4.

Stepwise regression analysis showed that damage to acetabular or femoral articular cartilage significantly affected the progression of arthritis. We conclude that the short-term results of successful rotational acetabular osteotomy for dysplasia are affected by the state of the articular cartilage.

We studied nine patients who had had a transtrochanteric anterior rotational osteotomy, as developed by Sugioka, for osteonecrosis of the femoral head. At a mean of 2.5 years after the initial operation we carried out a histological study of the previously necrotic femoral head which had not shown collapse of the new primary weight-bearing site. In seven joints, there was proliferation of fibrous tissue in the dead trabeculae with vascular ingrowth. New bone covering dead trabeculae created the characteristic appearance of ‘creeping substitution’. However, these changes were limited and did not extend over the entire necrotic area. Dead bone remained in all the cases. In the other two heads we did not observe proliferation of fibrous tissue or vascular ingrowth, only dead trabeculae and dead bone marrow.

We report the use of a new approach for elbow arthroplasty in 58 cases over a 20-year period. A wide exposure, obtained by elevating the triceps attachment and dividing the radial collateral ligament, allows the excision of diseased tissue, articular irregularities and osteophytes. Normal anatomy is restored and active mobilisation can be started 10 days after operation. Good or fair results, with over 70 degrees of joint movement, were achieved in 88% of cases.