Periprosthetic joint infection (PJI) remains challenging as a “gold standard” for diagnosis has not yet been established. The aim of this study was to evaluate the accuracy of synovial fluid procalcitonin (SF-PCT) and serum procalcitonin as diagnostic biomarker for PJI and compared their accuracy with standard methods. A single-centered prospective cohort study was conducted between 2015–2017 in 32 patients with painful hip or knee arthroplasty underwent revision surgery. Relevant clinical and laboratory data were collected. PJI was diagnosed based on the 2013 international consensus criteria. Preoperative blood sample and intraoperatively acquired joint fluid were taken for PCT measurement with a standard assay. Diagnostic accuracy was analyzed by the receiver-operating characteristic (ROC) curve and the area under the curve (AUC).Background
Materials and Methods
