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Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 530 - 530
1 Oct 2010
Stucinskas J Clauss M Ilchmann T Ochsner P Tarasevicius S Wingstrand H
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Introduction: Changes of the proximal femur like oste-olysis, stress shielding and osteopenia are frequently observed after total hip arthroplasty (THA). Such find-ings might be considered as risk factors for aseptic loosening and later revision. Cortical thinning is observed of healthy femora too and it is questioned whether the effect of the implant can be discriminated from age-related changes.

Aim of our study was to analyze cortical bone changes in prosthetic hips with time and compare those changes with the contra lateral non operated femur.

Materials and Methods:From 1984–87 165 hips were operated with a cemented Muller straight stem. Regular clinical and radiological follow up was scheduled after 1, 2, 5, 10, 15 years. We included only patients operated for osteoarthritis without revision and complete follow-up of more than 10 years. 37 THA hips in 35 patients remained for inclusion in the study. The mean follow-up was 16±4,6 years. Thickness of cortices was measured medially and laterally in 6 locations according to the 2nd to 6th Gruen zones and mean cortical thinning was calculated. The measurements were taken on standardized anterior-posterior x-rays of the pelvis. All measurements were analyzed with Image Access 4 Software calibrated with the reference to 32 mm femoral head.

10 patients were not operated on the contralateral hip and were measured in standardized manner in the same locations as in THA femurs.

Results: All included patients had pain free hips and did not require revision surgery at the last follow-up. Mean cortical thinning was 0,17±0,15 mm/year and it was mostly expressed in mid part of the stem (Gruen 2 and 6 zones). Most thinning occurred within the first 5 years (0,32±0,34 mm/year), later thinning was slower (0.09±0,37 mm/year). For the group with non operated contralateral hip mean thickness loss in THA hip was 0,2±0,17 mm/year and there was thickness loss of the contralateral femur too (0,03±0,12 mm/year), being much less as compared to the operated side (p< 0.001).

Conclusions: Loss of cortical thickness in THA hip with the Muller straight stem is frequently observed in long term and is not associated to expression of clinical symptoms and subsequent revision surgery. The effect is pronounced in the first postoperative years, mainly being explained by stress shielding. Additionally there is cortical thinning due to ageing, being much less than the influence of the implant. Thinning of the cortical bone must not be interpreted a sign of aseptic loosening.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 301 - 301
1 May 2010
Hommel A Ulander K Bjorkelund K Norrman P Wingstrand H Thorngren K
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Hip fractures constitute a major cause of hospital admission and length of stay in the elderly, resulting in increased disability and mortality. In this study the influence of optimized treatment of consecutively included patients with hip fracture on time to operation, bed days, reoperations and mortality within one year were investigated. The study period was April 1st 2003 and March 31st 2004. Comparisons are made between the 210 first patients and the 210 last patients who followed the new clinical pathway introduced at the University Hospital in Lund, Sweden. Early surgery, within 24 hours, was not associated with reduced mortality, but it was significantly associated with reduced length of stay (p< 0.001). Significantly more patients operated with osteosynthesis for femoral neck fracture, were reoperated compared to all other types of surgery (p< 0.001) also when reoperations with extraction of the hook-pins in healed fractures were excluded. Mortality was higher in men than in women at four (p = 0.025) and twelve months (p = 0.001) after the fracture. Mortality was significantly higher in medically fit patients with administrative delay to surgery compared to patients with no delay (p< 0.001).


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 65 - 66
1 Mar 2009
Tarasevicius S Robertsson O Kesteris U Kalesinskas R Wingstrand H
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Background: The role of polyethylene (PE) wear in relation to synovitis and elevated hydrostatic pressure in the loosening process after THA has gained increased attention. The aim of our study was to investigate the correlation between prosthetic head size, PE wear and sonographic capsular distention, reflecting the degree of intracapsular synovitis/synovia/hydrostatic pressure.

Patients and methods: In 2005 we analyzed 60 randomly selected and unrevised OA patients 10 years after surgery with 32 or 28mm femoral heads. We evaluated radiographic signs of loosening, linear and volumetric PE wear. Sonographic examination was performed to measure the “capsular distance”, i.e. the capsular distension, defined as the distance between the metallic echo from the anterior surface of the prosthetic femoral neck, and the echo from the anterior surface of the anterior capsule.

Results: The linear wear was 0.2 mm per year and 0.1 mm per year in the 32 mm and 28 mm head size group respectively (p< 0.001), the volumetric wear was 139 mm3/year and 48 mm3/year (p< 0.001), and the capsular distention was 17 mm and 13 mm respectively (p< 0.001). There was also a significant positive correlation between PE volumetric wear and capsular distension (r=0.63, p< 0.001).

Interpretation: We conclude that 32 mm femoral heads were associated with almost three times higher volumetric wear as compared to 28 mm heads, and increased “capsular distension”, reflecting increased synovitis/synovia/hydrostatic pressure in prosthetic hip.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 173 - 173
1 Mar 2009
Tarasevicius S Kesteris U Robertsson O Wingstrand H
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Introduction. Since the early days of total hip arthroplasty (THA) the choice of the proper diameter of the femoral head has been debated with respect to its effect on wear. The most widely accepted theory explaining aseptic loosening of THA is that of polyethylene particles induced osteolysis. In a previous study concerning 1,660 ScanHip THA’s that were followed for up to 12 years the cumulative revision rate was not found to be dependent on if a 22 mm or a 32 mm head size had been used1. We have reexamined these patients to see whether a longer follow-up time (9–21 years) would disclose an effect of head size on the revision rate.

Patients and Methods. We analyzed the CRR for 1,720 Scan Hip® Classic I THA implanted in 1,550 patients, with 22 and 32mm heads, performed at Lund University Hospital during 1983 to 1995. Patients with the 3 most common diagnoses were included in the analysis, i.e. osteoarthritis, rheumatoid arthritis and femoral neck fracture. The end-point was defined as revision of any component for aseptic loosening before the end of 2004.

Results. Using the life table method analyzed cumulative revision rate for osteoarthritis, femoral neck fracture and rheumatoid arthritis patients and found that the 32 mm head had higher cumulative revision rate (p=0.04 (Wilcoxon)). Further analysis with Cox regression adjusting for age and sex showed that the 32 mm head had 2.8 times greater risk of revision (CI 1.7–4.6), p< 0.001. For each year increase in age the risk of revision was reduced 0.96 times (CI 0.95 – 0.97), p< 0.001, males had 1.5 times (CI 1.1 – 2.1), p=0.01 greater risk of revision than females.

Discussion. The reason that we did not find any significant difference in cumulative revision rates when followed up to 12 years, depending on head size in previous study (Kesteris et al. 1998) may be the time it takes for wear particles to induce the chain of events, eventually ending up in loosening. However extended follow-up up to 21 years after THA revealed significant differences in cumulative revision rates depending on head size.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 4 | Pages 461 - 466
1 Apr 2007
Tsuboi M Hasegawa Y Suzuki S Wingstrand H Thorngren K

We studied prospectively the change over ten years in mortality, walking ability and place of residence after a hip fracture in 753 patients in Japan. We compared the deaths observed in these patients with those expected in the general population, matched for age, gender and calender year at the time of fracture. The survival rate decreased dramatically for two years after the event and the mortality risk remained higher for ten years. This risk was approximately double that of the general population, even at ten years after fracture. The risk was higher, and remained so for longer, in younger rather than in older patients.

The proportion of patients who were able to walk outdoors alone, with or without an assistive device, was 68% (514) before fracture. This decreased to 56% (340) by one year after and remained stable at approximately 63% (125) until ten years. The proportion of patients living in their own home was 84% (629) before fracture, 81% (491) one year later, and then remained stable at approximately 86% (171) until ten years after the event.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 206 - 206
1 Mar 2004
Jalovaara P Partanen J Heikkinen T Wingstrand H Thorngren K
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Aims: To find out if osteosynthesis (OS) or hemiarthroplasty (HA) is better in terms of functional outcome. Patients and methods: In 1989–1996, all displaced cervical hip fractures were prospectively, using the same forms, registered at the University Hospitals of Oulu in Finland and Lund in Sweden. Cross-matchings was performed for age, sex, preoperative residence, and ambulatory capacity. Results: The first study comprised 357 pairs (OS with two hook pins and cementless Austin-Moore HA): OS was associated with a better functional outcome and lower mortality, but a higher re-operation rate than hemiarthroplasty. The second study had 446 pairs (OS two hook pins and cemntless HA): OS was associated with better function and lower mortality than HA, especially in younger patients, and it is recommended as the primary treatment for cervical non-pathological hip fractures in patients younger than 80 years and with good ambulatory capacity, whereas the oldest patients can also be safely treated by HA. The third study comprised 82 pairs (OS with three screws and cementless HA): Functional recovery is slightly better after OS with three screws than after uncemented HA, although no significant differences were seen in a sample of this size. On the other hand, OS is associated with a higher re-operation rate. Conclusion: OS seemed somewhat better in terms of functional outcome.


The Journal of Bone & Joint Surgery British Volume
Vol. 80-B, Issue 3 | Pages 377 - 381
1 May 1998
Ilchmann T Markovic L Joshi A Hardinge K Murphy J Wingstrand H

We analysed in-vivo migration and wear over a long period of all-polyethylene acetabular cups which had not been affected by mechanical loosening. The selection criteria of regular radiological follow-up, good clinical outcome (Charnley score of 5 or 6), continued walking without crutches and no radiological signs of loosening of the acetabular cups were fulfilled by 25 Charnley total hip arthroplasties.

Mean migration, measured by the Nunn method, was 0.6 mm in the medial and 0.2 mm in the cranial direction. The mean yearly rate of wear was 0.05 mm and 0.04 mm, with six and two cups having no detectable wear, as measured by the Livermore and Charnley-Cupic methods, respectively. The maximal detected wear was 3.7 mm. There were no changes in the rate of wear with time. Computerised Ein Bild Röntgen Analyse (single-image radiological analysis) measurements of 20 hips indicated plastic deformation of the cups.

We conclude that long-term successful cups do not migrate and have a very low rate of wear which was not affected by ageing of the polyethylene. There was no evidence that polyethylene wear alone caused mechanical loosening of the cup but high rates of wear seem to have an adverse prognostic value in terms of the long-term survival of the prosthesis.


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 3 | Pages 379 - 382
1 May 1990
Egund N Nilsson L Wingstrand H Stromqvist B Pettersson H

Computed tomography was performed on 40 patients with recent hip trauma. Radiographs of 25 showed a fracture of the femoral neck with slight displacement; 24 of these had intra-articular fluid and 20 had a lipohaemarthrosis on the CT scan. In 15 patients, radiographs at the time of admission were normal but suspicion of fracture remained. A fracture was later verified in five patients, four of whom had lipohaemarthrosis on admission. In the remaining 10 patients no fracture could be detected; only one patient had a hip joint effusion but no free fat. Thus all 24 patients with lipohaemarthrosis had an intracapsular fracture of the hip. We suggest CT for patients with hip trauma and negative radiographs. The presence of a lipohaemarthrosis of the hip strongly suggests an intra-articular fracture of either the femoral neck or the acetabulum.


The Journal of Bone & Joint Surgery British Volume
Vol. 70-B, Issue 2 | Pages 192 - 194
1 Mar 1988
Stromqvist B Nilsson L Egund N Thorngren K Wingstrand H

We studied intracapsular pressure in 50 patients with Garden Grade I and II subcapital fractures. Before operation pressures varied from zero to 320 mmHg, 16 patients having an intracapsular pressure of over 80 mmHg. The pressure was increased considerably by medial rotation and decreased by lateral rotation and especially by semi-flexion. From zero to 36 ml of blood was aspirated; the amount did not correlate with the intracapsular pressure. Of 25 patients who were also examined by scintimetry, 13 had reduced uptake at the femoral head before aspiration, and nine of these showed a marked increase in uptake after aspiration. Intracapsular tamponade of the hip may be one reason for the occasional occurrence of segmental collapse of the femoral head after subcapital fracture with minor displacement.


The Journal of Bone & Joint Surgery British Volume
Vol. 69-B, Issue 2 | Pages 254 - 256
1 Mar 1987
Wingstrand H Egund N Forsberg L

Sonography was successfully used to diagnose an effusion in the hips of three adults with septic arthritis and four with aseptic synovitis. The effusions were confirmed by aspiration. All the patients had markedly increased intracapsular pressure which, in the extended position, exceeded the systolic blood pressure and could well compromise the blood supply to the head of femur. Aspiration reduced pain and intracapsular pressure, as did flexion of the hip to 45 degrees.