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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIII | Pages 173 - 173
1 May 2012
Zheng M Willers C
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Objective

To investigate the histological and immunohistochemical characteristics of revised and failed MACI repair tissues.

Methods

We examined the matrix profiles of repair biopsies taken from revised and clinically failed MACI cases by semi-quantitative immunohistochemical study using antibodies specific to aggrecan, collagens I, II, III, VI, and IX, Sox-9, Ki-67 and MMP-13. We also stiffness tested an intact clinically failed repair site.