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Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_7 | Pages 11 - 11
1 May 2018
Alvand A Grammatopoulos G Quiney F Taylor A Whitwell D Price A Dodd C Jackson W Gibbons M
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Endoprosthetic replacement (EPR) is an available option for the management of massive bone loss around failed knee implants. The aim of this study was to determine the results of knee EPRs performed for non-tumour indications. Since 2007, 85 EPRs were performed for in a single tertiary centre by seven surgeons. Mean age at surgery was 73.5 years (range:35–95) with infection as the most common indication (49%), followed by aseptic loosening (18%), complex primary replacement (16%), fracture (15%) and mechanical failure (2%). Mean follow up was 4 years (range:1–9). Functional outcome was determined using the Oxford Knee Score (OKS). At follow-up, 21 patients were deceased and 2 lost to follow-up. Complication rate was 19%. Of the 7 infected cases, 6 were treated with DAIR (debridement, antibiotics, and implant retention) and one underwent above knee amputation. Four of the patients undergoing DAIR were cleared of infection and 2 are on long-term antibiotics. Accounting for implant revision, loss to follow-up and those on long-term antibiotics as failures, 5-year survival was 89% with an average OKS of 25 (SD=10). This mid-term study shows that distal femur EPR is a valuable option for the increasing burden of complex revision knee surgery


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_23 | Pages 4 - 4
1 Dec 2016
Alvand A Grammatopoulos G de Vos F Scarborough M Athanasou N Kendrick B Price A Gundle R Whitwell D Jackson W Taylor A Gibbons M
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Introduction

The burden of peri-prosthetic joint infection (PJI) following hip and knee surgery is increasing. Endoprosthetic replacement (EPR) is an option for management of massive bone loss resulting from infection around failed lower limb implants.

Aims

To determine clinical outcome of EPRs for treatment of PJI around the hip and knee joint.


The Bone & Joint Journal
Vol. 95-B, Issue 5 | Pages 714 - 717
1 May 2013
Yates P Kellett C Huntley JS Whitwell D Reed MR Beadel G Snyckers C

In May 2012, in airports across the globe, seven orthopaedic surgeons bravely said goodbye to their loved ones, and slowly turned towards their respective aircraft. Filled with expectation and mild trepidation they stepped into the unknown… the ABC fellowship of 2012.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 96 - 96
1 Jan 2013
Palmer A Thomas G Whitwell D Taylor A Murray D Price A Arden N Glyn-Jones S
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Introduction

Hip arthroscopy is a relatively new procedure and evidence to support its use remains limited. Well-designed prospective clinical trials with long-term outcomes are required, but study design requires an understanding of current practice. Our aim was to determine temporal trends in the uptake of non-arthroplasty hip surgery in England between 2001 and 2011.

Methods

Using procedure and diagnosis codes, we interrogated the Hospital Episode Statistics (HES) Database for all hip procedures performed between 2001 and 2011, excluding those relating to arthroplasty, tumour or infection. Osteotomy procedures were also excluded.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 119 - 119
1 Jan 2013
Bayliss L van Drunen G Whitwell D Giele H Gibbons M van de Sande M
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Segmental excision of long-bone sarcomas can require complex reconstruction, often resulting in the use of prosthetic replacements at a young age.

The use of vascularised free fibula grafting (VFFG) is well established as a reconstruction modality in sarcoma surgery.

Aims

To analyse the experience of two European sarcoma centres and their use of vascularised free fibula grafting as a primary and revision procedure in limb salvage for diaphyseal long-bone defects in sarcoma surgery.

Methods

A retrospective analysis was carried out of 70 consecutive patients undergoing VFFG between 1996 and 2009 under the Oxford Sarcoma Service (Nuffield Orthopaedic Centre) and the Dutch Orthopaedic Tumour Society (Leiden University Hospital). Clinical and radiological assessments were made and functional outcome scores collected.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 120 - 120
1 Jan 2013
Bayliss L Thomas S Whitwell D Giele H Gibbons M
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Aims

Delays to diagnosis and management of soft tissue sarcomas are preventable but still occur. The introduction of a referral proforma to the Thames Valley Cancer Network in 2005 and National guidelines in 2006 aimed to decrease the incidence of partially and inadequately managed soft tissue sarcomas. This study aims to assess referrals for partially or inadequately managed soft tissue sarcomas and their subsequent management.

Methods

A prospective analysis of all patients referred to the Oxford Sarcoma Service following inadvertent excision of a soft tissue sarcoma between January 2010 and August 2011 was carried out. Pre-operative investigation and subsequent secondary managements were recorded. Patients with a diagnosis of dermatofibrosarcoma protuberans were excluded.


The Journal of Bone & Joint Surgery British Volume
Vol. 81-B, Issue 6 | Pages 1035 - 1040
1 Nov 1999
Atkins RM Madhavan P Sudhakar J Whitwell D

The ipsilateral and contralateral fibulae have been used as a vascularised bone graft for loss of tibial bone usually by methods which have involved specialised microvascular techniques to preserve or re-establish the blood supply.

We have developed a method of tibialisation of the fibula using the Ilizarov fixator system, ipsilateral vascularised fibular transport (IVFT), and have used it in five patients with massive loss of tibial bone after treatment of an open fracture, infected nonunion or chronic osteomyelitis. All had successful transport, proximal and distal union, and hypertrophy of the graft without fracture. One developed a squamous-cell carcinoma which ultimately required amputation of the limb.

The advantage of IVFT is that the fibular segment retains its vascularity without the need for microvascular dissection or anastomoses. Superiosteal formation of new bone occurs if the tibial periosteal bed is retained. Other procedures such as corticotomy and lengthening can be carried out concurrently.