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The Bone & Joint Journal
Vol. 98-B, Issue 6 | Pages 754 - 760
1 Jun 2016
Malek IA Royce G Bhatti SU Whittaker JP Phillips SP Wilson IRB Wootton JR Starks I

Aims

We assessed the difference in hospital based and early clinical outcomes between the direct anterior approach and the posterior approach in patients who undergo total hip arthroplasty (THA).

Patients and Methods

The outcome was assessed in 448 (203 males, 245 females) consecutive patients undergoing unilateral primary THA after the implementation of an ‘Enhanced Recovery’ pathway. In all, 265 patients (mean age: 71 years (49 to 89); 117 males and 148 females) had surgery using the direct anterior approach (DAA) and 183 patients (mean age: 70 years (26 to 100); 86 males and 97 females) using a posterior approach. The groups were compared for age, gender, American Society of Anesthesiologists grade, body mass index, the side of the operation, pre-operative Oxford Hip Score (OHS) and attendance at ‘Joint school’. Mean follow-up was 18.1 months (one to 50).


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 35 - 35
1 Mar 2010
Whittaker JP McAuley JP Naudie D McCalden RW MacDonald SJ Bourne RB
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Purpose: The results of medial unicompartmental knee replacement have been reported as excellent over the intermediate term with both fixed and mobile bearing designs. However not all publications report equal success, with different outcomes also reported between mobile and fixed bearing designs. The purpose of this study was to compare the outcomes of mobile and fixed bearing medial unicompartmental arthroplasties.

Method: We evaluated the results of 230 consecutive medial unicompartmental knee arthroplasties (UKA) designs performed between 1989 and 2006 at a single academic centre (London Health Sciences Centre). Eighty mobile bearing UKA (63 patients, mean follow up3.2 years) and 160 fixed bearing UKA (117 patients, mean follow up 6.2 years) were reviewed. The mean age of the patients at the time of surgery was 66 years. Forty nine patients died at a mean of 12.7 years after the index arthroplasty. Patients were evaluated clinically using the Knee Society, WOMAC and SF12 outcome scores and radiographically using the Knee Society rating system.

Results: In the fixed bearing group 21 knees underwent revision at a mean of 6.9 years after the index procedure. In the mobile bearing group 7 knees underwent revision at a mean of 2.6 years. The mean Knee Society knee and function scores for the patients who had not had a revision improved in both groups, with the fixed bearing group mean function and Knee Society Scores improving from 53 and 48 points preoperatively to 80 and 93 points at the time of the most recent evaluation. In the mobile bearing group the mean function and Knee Society Scores improved from 55 and 44 points preoperatively to 85 and 91 points at the time of the most recent evaluation. The five year cumulative survival rates were 96% (SE +/− 0.18) and 89% (SE +/− 0.46) for the fixed and mobile bearing designs respectively, with ten year cumulative survival rates of 85% (SE +/− 0.35) in the fixed bearing group using an endpoint of revision to tricompartmental knee arthroplasty.

Conclusion: Both bearing designs of medial unicompartmental knee arthroplasty provided excellent pain relief and restoration of function in carefully selected patients and demonstrated durable implant survival over the midterm. In this study the fixed bearing designs demonstrated improved survivorship over the mobile bearing designs at 5 years. This may be related to the learning curve of the different bearing systems.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 1 | Pages 44 - 51
1 Jan 2009
Whittaker JP Warren RE Jones RS Gregson PA

When using a staged approach to eradicate chronic infection after total hip replacement, systemic delivery of antibiotics after the first stage is often employed for an extended period of typically six weeks together with the use of an in situ antibiotic-eluting polymethylmethacrylate interval spacer. We report our multi-surgeon experience of 43 consecutive patients (44 hips) who received systemic vancomycin for two weeks in combination with a vancomycin- and gentamicin-eluting spacer system in the course of a two-stage revision procedure for deep infection with a median follow-up of 49 months (25 to 83).

The antibiotic-eluting articulating spacers fractured in six hips (13.9%) and dislocated in five patients (11.6%). Successful elimination of the infecting organisms occurred in 38 (92.7%) of 41 hips with three patients developing superinfection with a new organism.

We conclude that prolonged systemic antibiotic therapy may not be essential in the two-stage treatment of a total hip replacement for Gram-positive infection, provided that a high concentration of antibiotics is delivered locally using an antibiotic-eluting system.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 8 | Pages 981 - 987
1 Aug 2008
Whittaker JP Dharmarajan R Toms AD

The management of bone loss in revision replacement of the knee remains a challenge despite an array of options available to the surgeon. Bone loss may occur as a result of the original disease, the design of the prosthesis, the mechanism of failure or technical error at initial surgery. The aim of revision surgery is to relieve pain and improve function while addressing the mechanism of failure in order to reconstruct a stable platform with transfer of load to the host bone. Methods of reconstruction include the use of cement, modular metal augmentation of prostheses, custom-made, tumour-type or hinged implants and bone grafting.

The published results of the surgical techniques are summarised and a guide for the management of bone defects in revision surgery of the knee is presented.