We report a retrospective study of the major complications following one-stage and two-stage bilateral unicompartmental knee replacements (UKR). Between 1999 and 2008, 911 patients underwent 1150 UKRs through a minimally- invasive approach in our unit. Of these, 159 patients (318 UKRs) had one-stage bilateral UKR and 80 patients (160 UKRs) had two-stage bilateral UKRs. The remainder were unilateral UKRs. The bilateral UKR groups were comparable in age and ASA grade, but more females were in the two-staged group (p=0.019). Mechanical thromboprophylaxis was used in all cases. Major complications were recorded as death, pulmonary embolus, proximal deep vein thrombosis (DVT) and adverse cardiac events within 30 days of surgery. No statistical differences between the groups were found regarding operating surgeon, tourniquet time or minor complications (excepting distal DVT). Anaesthetic times were greater for the two-stage group (p= 0.0001). Major complications were significantly more common with one-stage bilateral UKR (13 patients, 8.2%) compared to two-stage bilateral UKR (no patients) (p=0.005). Distal DVT was more frequent in the two-stage group (p=0.036). This series reports significantly higher risks of major complications are associated with one-stage bilateral UKR when compared to two-stage bilateral UKR. There is no evidence that the addition of chemical thrombo-prophylaxis would change this risk. We advocate caution before undertaking a one-stage bilateral UKR.
Four hundred and twelve patients were included in the study. The mean Harris, VAS and HSS were significantly different between the failed and well fixed groups. However there was no statistically significant difference between the mean Oxford and MDA scores. ROC analysis demonstrated the Harris (0.97), VAS (0.98) and HSS (0.77) score to have good prediction of outcome.
Using Altman’s nomogram, the sample size was calculated to be 85 for a power of 90%, with an α significance level of 0.05. Using this database, digital radiographs were assessed using the institution’s PACS system. Pre-operative and follow-up skyline radiographs following Jones et al’s (1993) patellofemoral scoring system were examined by four assessors utilising Jones’ patellofemoral scoring system. In addition, in cases where patellofemoral joint changes were evident, each assessor acknowledged whether this involved the medial, lateral or bilateral aspects of the patellofemoral joint. Intra-observer reliability was made comparing the four assessors. Statistical analysis was performed, using the Statistical Package for the Social Sciences (SPSS) 16.0 for Windows (SPSS Inc, Chicago, Illinois). In order to determine whether changes in patellofemoral joint status related to patients function or quality of life, the difference in OKS and SF-12 from pre-operative to the follow-up period was assessed.
The objective of our study was to assess the efficacy of infection control measures (pre-admission screening and patient segregation) on reducing inpatient exposure to methicillin-resistant Staphylococcus aureus (MRSA). A prospective case-control study was undertaken, analysing all admissions to three wards over an 83-month period from September 1995 to July 2002 inclusive (a total of approximately 34 000 patients). An orthopaedic ward with active infection control measures was compared with two controls, an orthopaedic ward with no measures and a general surgical ward with no measures. A statistical analysis was performed of the difference between the 3 wards in numbers of new cases of MRSA infection or colonisation. There was a statistically significant difference in numbers of new cases between the ward with the active infection control measures and the two control wards. The infection control methods described are shown to reduce the exposure of patients to MRSA, which is of importance in orthopaedics, and has further benefits that may be applied in other surgical specialties, notably the choice of antibiotic used with the associated risk of side-effects of the specific anti-MRSA agents, the cost for surgical prophylaxis and patients’ confidence in the admitting surgical unit. As a useful by-product, such segregated inpatient beds are effectively ring-fenced, ensuring availability even during a hospital bed-shortage.