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Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_13 | Pages 50 - 50
1 Dec 2022
AlDuwaisan A Visva S Nguyen-Luu T Stratton A Kingwell S Wai E Phan P
Full Access

Symptomatic lumbar spinal stenosis is a common entity and increasing in prevalence. Limited evidence is available regarding patient reported outcomes comparing primary vs revision surgery for those undergoing lumbar decompression, with or without fusion. Evidence available suggest a lower rate of improvement in the revision group. The aim of this study was to assess patient reported outcomes in patients undergoing revision decompression, with or without fusion, when compared to primary surgery.

Patient data was collected from the Canadian Spine Outcomes Research Network (CSORN) database. Patients undergoing lumbar decompression without or without fusion were included. Patients under 18, undergoing discectomy, greater than two level decompressions, concomitant cervical or thoracic spine surgery were excluded. Demographic data, smoking status, narcotic use, number of comorbidities as well as individual comorbidities were included in our propensity scores. Patients undergoing primary vs revision decompression were matched in a four:one ratio according to their scores, whilst a separate matched cohort was created for those undergoing primary vs revision decompression and fusion. Continuous data was compared using a two-tailed t-test, whilst categorical variables were assessed using chi-square test.

A total of 555 patients were included, with 444 primary patients matched to 111 revision surgery patients, of which 373 (67%) did not have fusion. Patients undergoing primary decompression with fusion compared to revision patients were more likely to answer yes to “feel better after surgery” (87.8% vs 73.8%, p=0.023), “undergo surgery again” (90.1% vs 76.2%, P=0.021) and “improvement in mental health” (47.7% vs 28.6%, p=0.03) at six months. There was no difference in either of these outcomes at 12 or 24 months. There was no difference between the groups ODI, EQ-5D, SF 12 scores at any time point. Patients undergoing primary vs revision decompression alone showed no difference in PROMs at any time point.

In a matched cohort, there appears to be no difference in improvement in PROMS between patients undergoing primary vs revision decompression, with or without fusion, at two year follow-up. This would suggest similar outcomes can be obtained in revision cases.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 100 - 100
1 Jul 2020
Vu K Phan P Stratton A Kingwell S Hoda M Wai E
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Resident involvement in the operating room is a vital component of their medical education. Conflicting and limited research exists regarding the effects of surgical resident participation on spine surgery patient outcomes. Our objective was to determine the effect of resident involvement on surgery duration, length of hospital stay and 30-day post-operative complication rates.

This study was a multicenter retrospective analysis of the prospectively collected American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database. All anterior cervical or posterior lumbar fusion surgery patients were identified. Patients who had missing trainee involvement information, surgery for cancer, preoperative infection or dirty wound classification, spine fractures, traumatic spinal cord injury, intradural surgery, thoracic surgery and emergency surgery were excluded. Propensity score for risk of any complication was calculated to account for baseline characteristic differences between the attending alone and trainee present group. Multivariate logistic regression was used to investigate the impact of resident involvement on surgery duration, length of hospital stay and 30 day post-operative complication rates.

1441 patients met the inclusion criteria: 1142 patients had surgeries with an attending physician alone and 299 patients had surgeries with trainee involvement. After adjusting using the calculated propensity score, the multivariate analysis demonstrated that there was no significant difference in any complication rates between surgeries involving trainees compared to surgeries with attending surgeons alone. Surgery times were found to be significantly longer for surgeries involving trainees. To further explore this relationship, separate analyses were performed for tertile of predicted surgery duration, cervical or lumbar surgery, instrumentation, inpatient or outpatient surgery. The effect of trainee involvement on increasing surgery time remained significant for medium predicted surgery duration, longer predicted surgery duration, cervical surgery, lumbar surgery, lumbar fusion surgery and inpatient surgery. There were no significant differences reported for any other factors.

After adjusting for confounding, we demonstrated in a national database that resident involvement in surgeries did not increase complication rates, length of hospital stay or surgical duration of more routine surgical cases. We found that resident involvement in surgical cases that were generally more complexed resulted in increased surgery time. Further study is required to determine the relationship between surgery complexity and the effect of resident involvement on surgery duration.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_20 | Pages 71 - 71
1 Nov 2016
Garland K Roffey D Phan P Wai E Kingwell S
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Adverse events (AEs) following spine surgery are very common. It is important to monitor the incidence of AEs to ensure that appropriate practices are implemented to minimise AEs and improve patient outcomes. The Spine Adverse Events Severity System (SAVES) is a validated AE recording tool specifically designed for spine surgery and the Orthopaedic Surgical Adverse Events Severity System (OrthoSAVES) is a similar tool intended for general orthopaedic surgery. The main objective was to prospectively collect AE data from spine surgery patients using SAVES and OrthoSAVES and compare their viability and applicability for use. The longterm objective is to enhance patient safety by tracking AEs with a view towards potentially changing future healthcare practices to eliminate the risk factors for AEs.

For a 10-week period in June-September 2015, three spine surgeons used SAVES to record AEs experienced by any elective spine surgery patients. In addition, a trained independent clinical reviewer with access to electronic records, medical charts, and allied health professionals (e.g. nurses, physioterhapists) used SAVES and OrthoSAVES to record AEs for the same patients. At discharge, the SAVES forms from the surgeons and SAVES and OrthoSAVES forms from the independent reviewer were collected and all AEs were recorded in a database.

In 48 patients, the independent reviewer recorded a total of 45 AEs (4 intra-operative, 41 post-operative), compared to the surgeons who recorded a total of 8 AEs (2 intra-operative, 6 post-operative) (P2) were recorded by both the independent reviewer and surgeons. OrthoSAVES had the capacity to directly record 3 additional AEs that had to be included in the “Other” section on SAVES.

SAVES and OrthoSAVES are valuable tools for recording AEs. Use of SAVES and OrthoSAVES has the potential to enhance patient care and safety by ensuring AEs are followed by the surgeon during their in-hospital stay and prior to discharge. Independent reviewers are more effective at capturing AEs following spine surgery, and thus, could be recruited in order to capture more AEs and maximise different complication diagnoses in alignment with proposed diagnosis-based funding models. The next step is to analyse AE data identified by the hospital discharge abstract to determine whether retrospective administrative coding can adequately record AEs compared to prospectively-collected AE data with SAVES/OrthoSAVES.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_20 | Pages 21 - 21
1 Nov 2016
Chen B Garland K Roffey D Poitras S Lapner P Dervin G Phan P Wai E Kingwell S Beaulé P
Full Access

The Spine Adverse Events Severity System (SAVES) and Orthopaedic Surgical Adverse Events Severity System (OrthoSAVES) are standardised assessment tools designed to record adverse events (AEs) in orthopaedic patients. The primary objective was to compare AEs recorded prospectively by orthopaedic surgeons compared to trained independent clinical reviewers. The secondary objective was to compare AEs following spine, hip, knee, and shoulder orthopaedic procedures.

Over a 10-week period, three orthopaedic spine surgeons recorded AEs following all elective procedures to the point of patient discharge. Three orthopaedic surgeons (hip, knee, and shoulder) also recorded AEs for their elective procedures. Two independent reviewers used SAVES and OrthoSAVES to record AEs after reviewing clinical notes by surgeons and other healthcare professionals (e.g. nurses, physiotherapists). At discharge, AEs recorded by the surgeons and independent reviewers were recorded in a database.

AE data for 164 patients were collected (48 spine, 52 hip, 33 knee, and 31 shoulder). Overall, 98 AEs were captured by the independent reviewers, compared to 14 captured by the surgeons. Independent reviewers recorded significantly more AEs than surgeons overall, as well as for each individual group (i.e. spine, hip, knee, shoulder) (p2), but surgeons failed to record minor events that were captured by the independent reviewers (e.g. urinary retention and cutaneous injuries; AEs Grade 0.05). AEs were reported in 21 (43.8%), 19 (36.5%), 12 (36.4%), and five (16.1%) spine, hip, knee, and shoulder patients, respectively. Nearly all reported AEs required only simple or minor treatment (e.g. antibiotic, foley catheter) and had no effect on outcome. Two patients experienced AEs that required invasive or complex treatment (e.g. surgery, monitored bed) that had a temporary effect on outcome.

Similar complication rates were reported in spine, hip, knee, and shoulder patients. Independent reviewers reported more AEs compared to surgeons. These findings suggest that independent reviewers are more effective at capturing AEs following orthopaedic surgery, and thus, could be recruited in order to capture more AEs, enhance patient safety and care, and maximise different complication diagnoses in alignment with proposed diagnosis-based funding models.


Background

Foraminal stenosis is often encountered in patients undergoing decompression for spinal stenosis. Given the increased resection of facets and the presence of the more sensitive dorsal root ganglion, it is hypothesized that patients with foraminal stenosis have poorer postoperative outcomes.

Methods

Thirty-one patients undergoing decompression without fusion for lumbar spinal stenosis were evaluated. The degree of foraminal stenosis was determined by 2 independent reviewers for absence of fat around the nerve roots. ImageJ digital imaging software was also used to evaluate the foraminal area. Patients with foraminal stenosis were compared with those without using the Oswestry Disability Index (ODI) and a numerical pain scale for back and leg pain at a minimum of 1 year follow-up.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 271 - 271
1 Jul 2011
Zeng Y Marion T Leece P Wai E
Full Access

Purpose: Persistent radiculopathy secondary to lumbar disc herniation is a common problem that greatly compromises quality of life. In North America, lumbar discectomies are among the most common elective surgical procedures performed. There is still much debate about when conservative or surgical treatments should be offered to patients. Although the related literature is comprehensive, there are limited systematic reviews on the prognostic factors predicting the outcome of lumbar discectomy. The purpose of this review is to define the preoperative factors predicting clinical outcome after lumbar discectomy.

Method: We conducted a computerized literature search using Ovid Medline and the Cochrane Central Register of Controlled Trials. We included randomized controlled trials or prospective studies dealing with lumbar disc surgery. The preoperative predictors had to be clearly identified and correlated with outcome measures in terms of pain, disability, work capacity, analgesia consumption, or a combination of these measures. We assessed the articles as high or low quality studies using the Newcastle-Ottawa Quality Assessment Scale, and summarized the results of High Quality Studies.

Results: A total of 39 articles were included. The two most prominent negative predictors were Workers’ Compensation status and depression according to 6 studies. Poor predictors reported in 4 articles were female gender, increasing age, and prolonged duration of leg or back pain. Lower education level, smoking, and higher levels of psychological complaints were negative predictors in 3 articles. A positive Lasègue sign was a positive predictor in 7 articles. Absence of back pain, positive patient expectations, and higher income were good prognostic factors in 3 studies. Patients with contained herniations did worse than those who had uncontained disc extrusions and sequestrations according to 4 studies. The level of herniation was not a predictive factor in 7 studies.

Conclusion: Workers’ Compensation, depression, greater back versus leg pain, increasing age, female gender, contained herniations, and prolonged symptoms predict unfavourable postoperative outcomes after lumbar discectomy. Positive Lasègue sign, higher income, uncontained herniations, and positive patient expectations predict favourable postoperative outcomes. The level of herniation is not an established prognostic factor. The results of this review provide a preliminary framework for patient selection for lumbar disc surgery.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 271 - 271
1 Jul 2011
Marion TE Zeng Y Wai E
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Purpose: Perispinal core muscle strength has been theorized to be an important component in the pathogenesis of back pain. Recent research has demonstrated a strong association between preoperative perispinal musculature, adjusted for fatty infiltration and prospective outcomes and improvements in back pain in patients undergoing lumbar laminectomy without fusion. The purpose of this study is to determine if a similar relationship exists in patients undergoing elective posterior lumbar fusion and decompression (PLFD) surgery.

Method: A retrospective observational study of prospectively collected outcomes data was conducted in which pre-operative function and patient variables of those undergoing PLFD were derived from a functional status questionnaire and medical records. ImageJ Digital Imaging Software was utilized to measure the total (CSA) and percentage of fatty infiltration of the psoas, multifidus, and erector spinae muscles in pre-operative L4 axial CT images. Pre-operative and post-operative lateral images were evaluated for degree of post-operative adjacent level degeneration. Follow-up consisted of a functional status questionnaire. Outcomes measured were improvements in back pain, leg pain, and Oswestry disability scores.

Results: Twenty-three patients were analyzed with a mean follow-up of 2 years (range 1 – 5 years). Outcomes improved following surgery. There were strong to moderate correlations between percentage of fat in the pre-operative posterior spinal muscles and improvements in leg pain (r = 0.63, p = < 0.001) and improvements in back pain (r = 0.41, p = 0.05). There was a moderate trend towards greater adjacent level degeneration (r = 0.37, p = 0.1) in patients with higher percentage of fat in the pre-operative posterior spinal muscles. There was a strong relationship between greater adjacent level degeneration and pre-operative disability as measured by the Oswestry (r = 0.62, p = 0.03).

Conclusion: The results demonstrate that a potential relationship exists between pre-operative fatty infiltration of posterior perispinal muscles and post-operative outcomes, and adjacent level degeneration following lumbar fusion surgery. This suggests that perispinal muscle atrophy and conditioning may play a role in these outcomes. Results may be used for prognostication, surgical candidate selection, and interventional strategies.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 29 - 29
1 Mar 2010
Wai E Sathiaseelan S Polis T Cardman R Chow D Johnson GE O’Neil J
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Purpose: Harvesting of iliac crest graft for spinal fusions is associated with a number of patients reporting residual pain at the harvest site. Various interventions have been proposed to minimize the pain associated with this. The purpose of this study was to evaluate the efficacy of intra-operative infiltration of morphine into the iliac crest harvest site for reduction of postoperative pain.

Method: A double-blinded, placebo controlled study was performed comparing intraoperative infiltration of 5mg of morphine (treatment) vs. saline (placebo) into the iliac crest harvest site for patients undergoing elective spinal surgery. Patients with myelopathy, excessive preoperative opiod use (60mg equivalent morphine/day or more), or multilevel (greater than 3 levels) spinal surgery were excluded. Postoperative administration of morphine (recovery room and PCA) was standardized. Numerical pain scores specific for the iliac crest site were determined in the immediate postoperative period and at 3, 6 and 12 months. Ad hoc power analysis demonstrated that 36 patients would be able to detect a clinically significant difference of 2.4 points on a 10 point numerical pain scale (alpha = 0.05, power = 80%).

Results: 37 patients were randomized and evaluated with a minimum of one year follow-up. The groups were similar in baseline age, gender and comorbidity. There was no significant difference between groups in total use of postoperative morphine during the first 24 hours (treatment: 320mg +/− 268mg, placebo: 293mg +/− 182mg, p = 0.73). There was no significant difference in iliac crest activity pain scores at 1 year (treatment: 1.7 +/− 3.0, placebo: 1.1 +/− 2.4, p = 0.48) or at any of the earlier time points. The proportion of patients with moderate to severe iliac crest pain at one year follow-up was the same between both groups.

Conclusion: This study has demonstrated that there are no additional benefits for the use of intra-operative infiltration of morphine into the iliac crest harvest site during spinal fusions.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 232 - 232
1 May 2009
Wai E Dent R Dornan H Gruszczynski A Vexler L
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Weight loss is commonly recommended as a treatment for back pain. However, there is little literature to support this. A recent systematic review has identified only studies relating to bariatric surgery. There are no other studies that address whether weight loss improves back pain.

Forty-five consecutive consenting patients were recruited following enrolment in a tertiary multidisciplinary weight management program. These patients were referred primarily for treatment of obesity. The program consisted of consultation and on-going supervision by a sub-specialty weight management physician, and group and individual sessions addressing diet, exercise and behaviour modification. Patients were assessed by independent observers prior to start of program and at twelve weeks into the program with standardised and validated outcomes tools measuring baseline factors, back pain and related functional disability at twelve weeks follow-up.

Prior to starting the program, forty-two patients (93%) reported some degree of low back pain of which 40% rated their pain as moderate (n = 12) or severe (n = 6). Using the Oswestry Low Back Pain Disability Index, 73% patients reported moderate (n = 18) or severe disability (n = 15). At twelve weeks, thirty-seven (82%) patients were available for assessment. There were significant improvement in VAS pain scores (mean change = 1.5, 95% CI: 0.7 to 2.4) and in Oswestry Low Back Disability Index (mean change= 8.6, 95% CI: 3.9 to 13.2). There were significant reductions in the prevalence of moderate or severe back pain (p = 0.04) and moderate or severe disability (p = 0.007) in the entire group.

This is the first study to provide empirical evidence on the positive effects of a weight loss program on back pain. These results lay the groundwork for longer follow-up and comparative studies.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 233 - 233
1 May 2009
Wai E
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The wait times between referral and initial consultation for a spinal surgeon are amongst the highest in the country. Moreover, the vast majority of patients seen by spinal surgeons are not considered appropriate surgical candidates and hence do not benefit from the surgeon’s expertise in surgical management. Identifying inappropriate patients as a method of “triage” may help reduce the wait times. This paper examines two possible “triage” mechanisms – (i.) questionnaire and (ii.) screening by an acute spine pain centre.

Phase I identified three simple questions, which were reliable at identifying leg and back dominant pain. These questions were independently administered to a consecutive cohort of fifty-two lumbar patients prior to consultation with one of four spinal surgeons at a tertiary academic centre. Phase II involved an acute spinal pain centre, staffed by pain specialists, who have been orientated on appropriate indications for referral. The mandate of this clinic was to assess patients with acute or subacute back pain within two weeks of referral. A similar questionnaire as the one used in Phase I was independently administered to the first ninety lumbar patients attending the clinic in Phase II. All patients were followed independently to determine if surgery was recommended or performed and compared against the baseline questionnaires, findings on CT/MRI scan or pain specialist’s referrals.

The questionnaire identified twenty (38.5%) patients with clearly back dominant pain in Phase I and 56 (62.2%) patients in Phase II. Of the eighteen patients that had surgery or were recommended to have surgery, none had clearly back dominant pain as identified by the questionnaire for a combined sensitivity of 100%. When compared against the patient’s CT/MRI scans in phase I and the pain specialists referrals in Phase II, the questionnaire was more accurate at identifying surgical candidates.

This study has demonstrated in multiple settings that a simple questionnaire of three questions can identify patients requiring surgery and may be more specific than standard referrals, CT/MRI scans, or pain specialist’s assessments. Further work is required to refine this screening process and evaluate it prospectively.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 46 - 46
1 Mar 2008
Kreder H Weller I Wai E
Full Access

The purpose of this study was to evaluate mortality following delay to surgery in hip fractures in the province of Ontario. All patients undergoing a surgical procedure for a hip fracture between 1993 and 1999 were identified using administrative databases. For every day that surgery was delayed, the adjusted odds of in-hospital mortality increased by a factor of 1.12 times (95%CI), with similar results at three months and one year. A significant relationship exists between delay to surgery and mortality in elderly hip fracture patients. Every effort should be made to avoid non-medical delays in providing operative treatment for hip fractures.

A significant relationship exists between delay to surgery and mortality in elderly hip fracture patients. Every effort should be made to avoid non-medical delays in providing operative treatment for patients with fractured hips.

This finding will have far reaching implications for the allocation of health resources in the future.

All patients undergoing a surgical procedure for a hip fracture between 1993 and 1999 in the Province of Ontario were identified using administrative databases and the provincial mortality database. Multivariable logistic regression models were used to adjust for age, gender, medical comorbidity, type of hip fracture, and teaching status of the treating hospital.

For every day that surgery was delayed, the adjusted odds of in-hospital mortality increased by a factor of 1.12 times (95% CI). The adjusted odds of in-hospital mortality increased as the delay to surgery lengthened from a factor of 1.2 [95% CI] with a one day delay to a factor of 1.5 [95% CI] for a delay over two days as compared with patients operated within twenty-four hours. Similar relationships were observed at three months and one year. Even when considering only healthy patients, < 70 years old with no comorbid conditions, the relationship between mortality and surgical delay remained significant (p < 0.0001), suggesting that surgical delay was unlikely to be caused by patient factors alone.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 118 - 118
1 Mar 2008
Wai E Gruscynski A Johnson G Chow D O’Neil J Vexler L
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Back pain is a complex problem affecting the majority of the population at some point in their life. This cross-sectional study evaluated patients presenting to a tertiary spine clinic with a primary complaint of back pain for modifiable lifestyle factors which may be associated with their back pain. Patients were also asked if any of these lifestyle factors had been addressed by primary care practitioners prior to referral to the spine surgeon’s office.

The purpose of this cross-sectional study is to evaluate the modifiable lifestyle factors which may be associated with back pain in patients presenting to a tertiary spine clinic with a primary complaint of back pain and to compare these lifestyle factors with the general population. A secondary objective is to determine whether patients with back pain were given any instructions with regard to modifiable lifestyle factors by their primary care practitioner.

Consecutive patients presenting to the orthopaedic spine surgery clinic at the Ottawa Hospital – Civic Campus are asked to complete a questionnaire upon presentation to the surgeon’s clinic and prior to their visit with the surgeon. Data being collected includes Body Mass Index, smoking history, physical activity history, perceived stress, and disability. Information is also being collected on sources of information about back pain including instructions given by primary care practitioners (physician, chiropractor, physiotherapist, massage therapist, acupuncturist, naturopath, and other). Data will be analyzed to determine the difference in modifiable risk factors between patients presenting to the spine surgery clinic and the general population. Data will also be tabulated for numbers of patients being given information on modifiable lifestyle factors by primary care practitioners.

To date fifty-two patients have completed the questionnaire. A significant difference has been noted between the number of morbidly obese (BMI > 30) patients presenting to the clinic and the general population. It has been noted that less than 20% of primary care physicians have talked about lifestyle modification with their patients prior to referring them to a spine surgeon.

It will be important to know what modifiable lifestyle risk factors this group of patients possesses and which of these modifiable lifestyle risk factors are actually being addressed by primary care practitioners prior to referral to spine surgeons.

The current waiting list for an appointment with a spine surgeon at the Ottawa Hospital is six to eighteen months. If surgeons can help primary care practitioners address some modifiable lifestyle factors with their patients prior to their referral, waiting times may be reduced or at the very least made more comfortable for patients.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 92 - 93
1 Mar 2008
Wai E Vexler L Fraser RD
Full Access

Independent reviewers performed systematic reviews of the abstracts presented at the annual meeting of the ISSLS and the CSS. Papers employing blinded or independent review of outcome were the strongest predictor of publication and papers employing this had an adjusted odds ratio of 4.7 for being published compared to those papers that did not. Other significant factors include use of an experimental design, statistically positive result, and basic science research.

To identify factors associated with eventual peer-reviewed publication in spinal research presented at national and international meetings.

This review has highlighted factors that are associated with eventual peer-reviewed publication. It will also present comparisons between the International Society for Study of the Lumbar Spine (ISSLS) and the Canadian Spine Society (CSS).

Independent reviewers performed systematic reviews of the abstracts presented at the annual meeting of the ISSLS and the CSS. All abstracts reviewed were categorized into type of research and aspects of research quality were identified. A medline database, blinded to the results of the review, was performed to identify abstracts that went onto peer-reviewed publication.

Univariate and multivariate analyses reviewed that blinding, use of an experimental design, basic science or biomechanical research, and a statistically significant positive result were significant predictors of eventual publication. Papers employing blinded or independent review of outcome were the strongest predictor of publication and papers employing this had an adjusted odds ratio of 4.7 for being published compared to those papers that did not. Other significant factors include use of an experimental design, statistically positive result, and basic science research. Overall, 23% of ISSLS’ abstracts were published within one year and 67% within two years. In contrast, 6% and 13% of CSS abstracts were published within one and two years respectively.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 46 - 47
1 Mar 2008
Weller I Kreder H Wai E Jaglal S Schatzker J
Full Access

We compared the mortality of hip fracture patients treated in teaching versus community hospitals in Ontario. Hip fracture patients ≥ 50 yrs were identified from the Canadian Institute for Health Information Hospital Discharge Abstracts Database and linked to the Registered Persons Database for death information. Logistic regression analyses were done to assess the relation between hospital type and both mortality and complications after surgery. Covariates examined include sex, age, Charlson-Deyo index, time to surgery and their interactions. Although patients treated in teaching hospitals have more comorbidities and complications they have lower mortality than those treated in community hospitals.

The purpose of this study was to compare the mortality of hip fracture patients treated in teaching versus urban and rural community hospitals in Ontario.

Although patients treated in teaching hospitals have more comorbidities and complications they have lower mortality than those treated in community hospitals.

This finding will have far-reaching implications for health policy in this province. Hip fracture (ICD-9 code 820) patients ≥ 50 yrs treated in Ontario between 1993 and 1999 were identified from the Canadian Institute for Health Information Hospital Discharge Abstracts Database. These were linked to the Registered Persons Database for death information. Logistic regression analyses were done to assess the relation between hospital type and both mortality and complications after surgery. Covariates examined include sex, age, Charlson-Deyo index, time to surgery and their interactions.

Patients treated in teaching hospitals and rural community hospitals were more likely to have a major complication than those in urban community hospitals, adjusted OR (95% CI) 1.37 (1.29–1.45); 1.28 (1.06–1.55) respectively. Patients in teaching hospitals had more comordities than those in community urban or rural hospitals. Nevertheless, patients treated in teaching hospitals have lower mortality (in hospital, and at three, six and twelve months post-surgery) than those in urban community hospitals, adjusted OR (95% CI) 0.76 (0.60–0.96), 0.90 (0.85–0.96), 0.91 (0.86–0.96), 0.92 (0.88–0.96) respectively. The difference between rural and urban community hospitals was not statistically significant, however there was a trend to higher mortality in rural institutions, adjusted OR (95% CI) 0.79 (0.63–1.00), 1.13 (0.95–1.36), 1.16 (0.98–1.36), 1.13 (0.97–1.32) respectively.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 74 - 74
1 Mar 2008
Kreder H Weller I Wai E
Full Access

The purpose of this study was to evaluate mortality following delay to surgery in hip fractures in the province of Ontario. All patients undergoing a surgical procedure for a hip fracture between 1993 and 1999 were identified using administrative databases. For every day that surgery was delayed, the adjusted odds of in-hospital mortality increased by a factor of 1.12 times (95%CI), with similar results at three months and one year. A significant relationship exists between delay to surgery and mortality in elderly hip fracture patients. Every effort should be made to avoid non-medical delays in providing operative treatment for hip fractures.

To evaluate mortality following delay to surgery in hip fractures in the province of Ontario.

A significant relationship exists between delay to surgery and mortality in elderly hip fracture patients. Every effort should be made to avoid non-medical delays in providing operative treatment for patients with fractured hips.

This finding will have far reaching implications for the allocation of health resources in the future.

All patients undergoing a surgical procedure for a hip fracture between 1993 and 1999 in the Province of Ontario were identified using administrative databases and the provincial mortality database. Multivariable logistic regression models were used to adjust for age, gender, medical comorbidity, type of hip fracture, and teaching status of the treating hospital.

For every day that surgery was delayed, the adjusted odds of in-hospital mortality increased by a factor of 1.12 times (95% CI). The adjusted odds of in-hospital mortality increased as the delay to surgery lengthened from a factor of 1.2 [95% CI] with a one day delay to a factor of 1.5 [95% CI] for a delay over two days as compared with patients operated within twenty-four hours. Similar relationships were observed at three months and one year. Even when considering only healthy patients, < seventy years old with no comorbid conditions, the relationship between mortality and surgical delay remained significant (p < 0.0001), suggesting that surgical delay was unlikely to be caused by patient factors alone.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 74 - 74
1 Mar 2008
Weller I Kreder H Wai E Jaglal S Schatzker J
Full Access

We compared the mortality of hip fracture patients treated in teaching versus community hospitals in Ontario. Hip fracture patients ≥ 50 yrs were identified from the Canadian Institute for Health Information Hospital Discharge Abstracts Database and linked to the Registered Persons Database for death information. Logistic regression analyses were done to assess the relation between hospital type and both mortality and complications after surgery. Covariates examined include sex, age, Charlson-Deyo index, time to surgery and their interactions. Although patients treated in teaching hospitals have more comorbidities and complications they have lower mortality than those treated in community hospitals.

To compare the mortality of hip fracture patients treated in teaching versus urban and rural community hospitals in Ontario. Although patients treated in teaching hospitals have more comorbidities and complications they have lower mortality than those treated in community hospitals. This finding will have far-reaching implications for health policy in this province. Hip fracture (ICD-9 code 820) patients ≥ 50 yrs treated in Ontario between 1993 and 1999 were identified from the Canadian Institute for Health Information Hospital Discharge Abstracts Database. These were linked to the Registered Persons Database for death information. Logistic regression analyses were done to assess the relation between hospital type and both mortality and complications after surgery. Covariates examined include sex, age, Charlson-Deyo index, time to surgery and their interactions.

Patients treated in teaching hospitals and rural community hospitals were more likely to have a major complication than those in urban community hospitals, adjusted OR (95% CI) 1.37 (1.29–1.45); 1.28 (1.06–1.55) respectively. Patients in teaching hospitals had more comordities than those in community urban or rural hospitals. Nevertheless, patients treated in teaching hospitals have lower mortality (in hospital, and at three, six and twelve months post-surgery) than those in urban community hospitals, adjusted OR (95% CI) 0.76 (0.60–0.96), 0.90 (0.85–0.96), 0.91 (0.86–0.96), 0.92 (0.88–0.96) respectively. The difference between rural and urban community hospitals was not statistically significant, however there was a trend to higher mortality in rural institutions, adjusted OR (95% CI) 0.79 (0.63–1.00), 1.13 (0.95–1.36), 1.16 (0.98–1.36), 1.13 (0.97–1.32) respectively.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 294 - 295
1 Sep 2005
Cain C Selmon G Wai E Hall D
Full Access

Introduction and Aims: Trans-laminar screw fixation is a popular method of posterior stabilisation when performing a 360-degree lumbar fusion, but many have concerns over the biomechanical stability of this construct. The objective of this paper is to compare the fusion rate and clinical outcome of this method with pedicle screw fixation.

Method: During 2001, 31 patients underwent combined anterior and posterior fusion by the two senior surgeons for the treatment of discogenic low back pain. Anterior interbody fusion was performed using the Syncage LR in all patients. Sixteen patients underwent trans-laminar screw fixation posteriorly and 15 underwent pedicle screw fixation. Fusion was assessed by fine cut CT scan at one year post-operatively. Function was assessed with pre- and post-operative Low Back Outcome Score and visual analogue pain scores.

Results: The average follow-up was 15.5 months. The incidence of pseudarthrosis in the trans-laminar screw group was approximately 80% (15 out of 19 levels), compared to 20% (4 of 21 levels) in the pedicle screw group (p < 0.05). There were trends towards greater improvements in the LBOS and VAS scores in the pedicle screw group. There were two surgical complications in the trans-laminar screw group and one in the pedicle screw group

Conclusion: The use of trans-laminar screws is associated with a significantly higher rate of pseudarthrosis compared to pedicle screw fixation. Assessing fusion with fine cut CT scans has revealed a higher rate of pseudarthrosis with trans-laminar screw fixation than has previously been reported


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 324 - 324
1 Sep 2005
Kreder H Wai E Weller I
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Introduction and Aims: Surgical delays for non-medical reasons in the management of hip fractures may be detrimental to clinical outcomes. Prior literature is inconclusive, often because of insufficient power and failure to adjust for potential confounding factors. Our aim was to evaluate mortality following delay to surgery in hip fractures in the province of Ontario.

Method: All patients undergoing a surgical procedure for a hip fracture between 1993 and 1999 in the Province of Ontario were identified using administrative databases and the provincial mortality database. Multivariable logistic regression models were used to adjust for age, gender, medical comorbidity, type of hip fracture, and teaching status of the treating hospital.

Results: For every day that surgery was delayed, the adjusted odds of in-hospital mortality increased by a factor of 1.12 times (95% CI). The adjusted odds of in-hospital mortality increased as the delay to surgery lengthened from a factor of 1.2 [95% CI] with a one-day delay to a factor of 1.5 [95% CI] for a delay over two days as compared with patients operated within 24 hours. Similar relationships were observed at three months and one year. Even when considering only healthy patients, < 70 years old with no comorbid conditions, the relationship between mortality and surgical delay remained significant (p < 0.0001), suggesting that surgical delay was unlikely to be caused by patient factors alone.

Conclusion: A significant relationship exists between delay to surgery and mortality in elderly hip fracture patients. Every effort should be made to avoid non-medical delays in providing operative treatment for patients with fractured hips. This finding will have far-reaching implications for the allocation of health resources in the future.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 309 - 310
1 Sep 2005
Weller I Kreder H Wai E Schatzker J Jaglal S
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Introduction and Aims: There is significant mortality during the first year after hip fracture. US studies indicate that mortality is lower in teaching than non-teaching hospitals for hip fracture patients. Our aim was to compare the mortality of hip fracture patients treated in teaching versus urban and rural community hospitals in Ontario.

Method: Hip fracture (ICD-9 code 820) patients ³ 50 yrs treated in Ontario between 1993 and 1999 were identified from the Canadian Institute for Health Information Hospital Discharge Abstracts Database. These were linked to the Registered Persons Database for death information. Logistic regression analyses were done to assess the relation between hospital type and both mortality and complications after surgery. Covariates examined include sex, age, Charlson-Deyo index, time to surgery and their interactions.

Results: Patients treated in teaching hospitals and rural community hospitals were more likely to have a major complication than those in urban community hospitals, adjusted OR (95% CI) 1.37 (1.29–1.45); 1.28 (1.06–1.55) respectively. Patients in teaching hospitals had more comordities than those in community urban or rural hospitals. Nevertheless, patients treated in teaching hospitals have lower mortality (in hospital, and at three, six and 12 months post-surgery) than those in urban community hospitals, adjusted OR (95% CI) 0.76 (0.60–0.96), 0.90 (0.85–0.96), 0.91 (0.86–0.96), 0.92 (0.88–0.96) respectively. The difference between rural and urban community hospitals was not statistically significant, however there was a trend to higher mortality in rural institutions, adjusted OR (95% CI) 0.79 (0.63–1.00), 1.13 (0.95–1.36), 1.16 (0.98–1.36), 1.13 (0.97–1.32) respectively.

Conclusion: Although patients treated in teaching hospitals have more comorbidities and complications they have lower mortality than those treated in community hospitals. These findings have enormous implications for healthcare providers and health policy-makers.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 491 - 491
1 Apr 2004
Wai E Santos E Fraser R
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Introduction Numerous in-vitro studies demonstrating increased stress at levels adjacent to a lumbar fusion have raised concerns of accelerated degeneration. However, the significance of this increased stress in the in-vivo setting remains unclear, especially with long-term follow-up. The objective of this study was to assess the level of degeneration on MRI in this same cohort of patients at a minimum of 20 years follow-up.

Methods Thirty-seven patients undergoing lower lumbar anterior lumbar interbody fusion with a minimum of 20 years follow-up were identified. Only patients with normal pre-operative discograms at the level adjacent to the fusion were considered in this study. MRI scans were performed and evaluated for any evidence of degeneration by an independent radiologist. Advanced degeneration was defined as either: (1) absence of T2 signal intensity in the disk, (2) disk herniation, or (3) spinal canal stenosis.

Results Advanced degeneration was identified in eight (22%) patients, with five (14%) being isolated to the adjacent level. Nineteen (51%) other patients had evidence of early degeneration in their lumbar spine. Overall, 10 (26%) patients had some evidence of degeneration isolated to the level adjacent to the disk whereas 17 (31%) patients had multilevel degeneration and six patients (16%) had degeneration in their lumbar spine but preservation of the adjacent level. There was no relationship between function and radiographic degeneration.

Conclusions Without a control group, it is difficult to make firm conclusions on whether the changes seen on MRI represent the natural history of spinal deterioration or represent accelerated degeneration. However, after 20 years, only a handful of patients developed advanced adjacent level degeneration. Furthermore, the majority of degenerative changes seen occurred over multiple levels or at levels not adjacent to the fusion, suggesting that changes seen may be more likely related to constitutional factors inherent within the individual as opposed to the increased biomechanical stresses at the adjacent levels.