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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 51 - 51
1 Mar 2017
Timperley A Doyle F Whitehouse S
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Introduction

Improvements in function after THA can be evaluated using validated health outcome surveys but studies have shown that PROMs are unreliable in following the progress of individuals. Formal gait lab analysis is expensive, time consuming and fixed in terms of location. Inertial Measurement Units (IMUs) containing accelerometers and gyroscopes can determine aspects of gait kinematics in a portable package and can be used in the outpatient setting (Figure 1). In this study multiple metrics describing gait were evaluated pre- and post THA and comparisons made with the normal population

Methods

The gait of 55 patients with monarthrodial hip arthrosis was measured pre-operatively and at one year post-surgery. Patients with medical co-morbidity or other condition affecting their gait were excluded. Six IMUs aligned in the sagittal plane were attached at the level of the anterior superior iliac spines, mid-thigh and mid-shank. Data was analysed using proprietary software (Figure 2). Each patient underwent a conventional THA using a posterolateral approach. An identical test was performed one year after surgery. 92 healthy individuals with a normal observed gait were used as controls.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_18 | Pages 25 - 25
1 Apr 2013
Elmorsy A Whitehouse S Timperley A Veitch S
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The design of hip replacements is based on the morphology of the proximal femur. Populations living in hard water regions have higher levels of serum calcium and magnesium which promote bone mineralization. A case control study was performed comparing proximal femoral morphology in patients living in soft and hard water regions to determine whether the effect of water hardness had an implication in the future design of hip-prostheses.

The proximal femoral morphology of 2 groups of 70 aged and sex matched patients living in hard and soft water regions at mean age 72.24 (range, 50 to 87 years) were measured using an antero-posterior radiograph of the non-operated hip with magnification adjusted.

The medullary canal diameter at the level of the lesser trochanter was significantly wider in patients living in the hard water region (mean width 1.9 mm wider; p=0.003). No difference was found at the isthmus, Dorr index, or cortical bone ratio.

In conclusion proximal femoral morphology does differ: a wider medullary canal at the level of the lesser trochanter in hard water regions. This size difference is relatively small and is unlikely therefore to affect the mechanics of the current femoral stem prostheses components.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 167 - 167
1 Sep 2012
Bolland B Whitehouse S Howell J Hubble M Gie G Timperley A
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This study utilised NJR primary hip data from the 6th Annual Report to determine the rate and indication for revision between cemented, uncemented, hybrid and resurfacing prosthetic groups. Regression analysis was performed to identify the influence of gender and ASA grade on these revision rates. Validity of the data was interrogated by exploring for episodes of misclassification.

Results

We identified 2,264 misclassified episodes within the four groups (Misclassification rate 2.7% primary, 4.3% revision procedures). Analysis was performed using the “reclassified dataset”.

The Kaplan-Meier revision rates at 3 years were 0.9% (95%CI: 0.8%-1.0%) for cemented prostheses, 1.9% (95%CI: 1.8%-2.0%) for uncemented hips, 1.2% (95%CI: 1.0%-1.4%) for hybrids and 3.0%, (95%CI: 2.7%-3.3%) in the resurfacing group. The trends in revision rates were comparable to those published in the NJR (6th Edn.) with significant differences across all groups (p< 0.0001). Revision rates in the under 55 year age group showed an identical hierarchy with cemented and hybrid arthroplasty having the lowest revision rates.

Cox Regression analysis indicated that both the prosthesis group in isolation and the interaction between prosthesis group and ASA grade significantly influenced the rate of failure (p< 0.001).

Indications for revision showed significant differences in rates for, pain, aseptic loosening, dislocation and malalignment between prosthesis types (p< 0.001). The indications including Aseptic loosening, pain, malalignment and dislocation all demonstrated similar trends in revision rates between prosthetic groups with cemented hips having the lowest rates followed by ascending rates for hybrid, uncemented and resurfacing groups. The exception being dislocation with resurfacings having the lowest revision rates.

Discussion

This study provides important baseline revision rates by indication for each prosthetic group from which future comparisons can be made. Areas of misclassification within the NJR dataset have been reported back for future annual analysis.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 168 - 168
1 Sep 2012
Bolland B Howell J Hubble M Timperley A Gie G Ling R
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Background

Since 1991 to 2008 approximately 800,000 Exeter stems have been sold worldwide with 80 reported cases of fracture (neck or stem). This study aimed to determine factors predisposing to fracture.

Method

Clinical, surgical, radiological and retrieval data was collated from Stryker Benoist-Girard and Exeter research databases. Risk factors associated with fracture were categorised to patient related (weight and activity levels), surgical related (poor medial support, component size, placement) and implant related (+ head).