Osseointegrated Amputation Prostheses can be functionalised by both biological augmentation and structural augmentation. These augmentation techniques may aid the formation of a stable skin-implant interface. Current clinical options are limited in restoring function to amputees, and are associated with contact dermatitis and infection at the stump-socket interface. Osseointegrated Amputation Prosthesis attempts to solve issues at the stump-socket interface by directly transferring axial load to the prosthesis, via a skin-penetrating abutment. However, development is needed to achieve a seal at the skin-implant interface to limit infection. Fibronectin, an Extracellular Matrix protein, binds to integrins during wound healing, with the RGD tripeptide being part of the recognition sequence for its integrin binding domain. Summary
Introduction
Office seating includes a variety of chair styles. There is limited research investigating their effects on spinal angles. Investigate effects of active (Swopper and Vari-Kneeler), and static (Saddle and a Standard Office) chairs on lumbo-pelvic and cervical regions.Background
Purpose of Study
