Aims

Tobacco, in addition to being one of the greatest public health threats facing our world, is believed to have deleterious effects on bone metabolism and especially on bone healing. It has been described in the literature that patients who smoke are approximately twice as likely to develop a nonunion following a non-specific bone fracture. For clavicle fractures, this risk is unclear, as is the impact that such a complication might have on the initial management of these fractures.

The three-dimensional (3D) correction of glenoid erosion is critical to the long-term success of total shoulder replacement (TSR). In order to characterise the 3D morphology of eroded glenoid surfaces, we looked for a set of morphological parameters useful for TSR planning. We defined a scapular coordinates system based on non-eroded bony landmarks. The maximum glenoid version was measured and specified in 3D by its orientation angle. Medialisation was considered relative to the spino-glenoid notch. We analysed regular CT scans of 19 normal (N) and 86 osteoarthritic (OA) scapulae. When the maximum version of OA shoulders was higher than 10°, the orientation was not only posterior, but extended in postero-superior (35%), postero-inferior (6%) and anterior sectors (4%). The medialisation of the glenoid was higher in OA than normal shoulders. The orientation angle of maximum version appeared as a critical parameter to specify the glenoid shape in 3D. It will be very useful in planning the best position for the glenoid in TSR.

Cite this article: Bone Joint J 2014;96-B:513–18.

Wear of polyethylene is associated with aseptic loosening of orthopaedic implants and has been observed in hip and knee prostheses and anatomical implants for the shoulder. The reversed shoulder prostheses have not been assessed as yet. We investigated the volumetric polyethylene wear of the reversed and anatomical Aequalis shoulder prostheses using a mathematical musculoskeletal model. Movement and joint stability were achieved by EMG-controlled activation of the muscles. A non-constant wear factor was considered. Simulated activities of daily living were estimated from in vivo recorded data.

After one year of use, the volumetric wear was 8.4 mm³ for the anatomical prosthesis, but 44.6 mm³ for the reversed version. For the anatomical prosthesis the predictions for contact pressure and wear were consistent with biomechanical and clinical data. The abrasive wear of the polyethylene in reversed prostheses should not be underestimated, and further analysis, both experimental and clinical, is required.

Introduction. Arthritis of the glenohumeral joint is usually associated with erosion and flattening of the articular surfaces. The aim of this study was to evaluate the influence of the articular flattening on the joint reaction forces and the humeral head translations during abduction and rotation.

Method. Analysis was conducted with a 3D finite element model of the shoulder, including the scapula, the humerus and 6 muscles: middle, anterior and posterior deltoid, supraspinatus, subscapularis, and infraspinatus. Both the glenoid and humeral head were eroded to artificially reproduce the flattening of an arthritic joint. Two situations were studied:

1) an intact joint with a radius of curvature of 24mm for the humeral head and 26mm for the glenoid;

Movements of external rotation (0–45°) and abduction (0–150°) were performed by muscles’ activation. Contact forces caused by muscles wrapping on bony surfaces were accounted for. Joints forces, glenohumeral contact point locations and humeral head translations were calculated for the intact and eroded joint.

Results: For the eroded joint, articular forces were up to seven times higher during rotation and five times higher during abduction. For the intact joint, the glenohumeral contact point and humeral head remained centred. On the other hand, for the eroded joint, eccentric contact points with large antero-posterior and supero-inferior humeral head translations were observed. Animated views showed that this fact was clearly related to the rocking-horse effect.

Conclusions: This study showed that flattening of the glenohumeral joint due to osteoarthritis increases dramatically the articular forces and humeral head translations. This phenomenon is by itself responsible for progression of the joint’s erosion and flattening and acts as a vicious cycle. It also partly explains the reduced range of motion observed clinically. Accordingly, to limit the risks of rocking-horse effect after shoulder arthroplasty, the joint’s reconstruction should restore a natural articular radius of curvature, with a centre of rotation in the middle of the humeral head.

Reversed shoulder prostheses are increasingly being used for the treatment of glenohumeral arthropathy associated with a deficient rotator cuff. These non-anatomical implants attempt to balance the joint forces by means of a semi-constrained articular surface and a medialised centre of rotation. A finite element model was used to compare a reversed prosthesis with an anatomical implant. Active abduction was simulated from 0° to 150° of elevation. With the anatomical prosthesis, the joint force almost reached the equivalence of body weight. The joint force was half this for the reversed prosthesis. The direction of force was much more vertically aligned for the reverse prosthesis, in the first 90° of abduction. With the reversed prosthesis, abduction was possible without rotator cuff muscles and required 20% less deltoid force to achieve it.

This force analysis confirms the potential mechanical advantage of reversed prostheses when rotator cuff muscles are deficient.

Bone tissue is known to adapt to a stress change with some time delay. In vivo experimental studies were conducted for measuring the effects of mechanical loading on bone remodelling. In parallel, numerous models were developed for simulating the long-term bone response to various physical activities. However, most of models neglected the delay of bone response and they were not fully identified with corresponding experimental measurement. The purpose of this work was to develop a model describing the delay between stress change and cortical bone response.

A mathematical model was developed, accounting for the delays for bone response to stress. For in vivo experiment, 80 female Wistar rats (9-week old) were randomly divided into a running and a control group. First group regimen consisted of treadmill running program: 1 hr. per day, 6 days a week during first 15 weeks (treadmill speed 1.6 km/h). At week 15, the running group rats were returned to normal activity (sedentary state in cages), during last 15 weeks. Rats of the control group were subjected to normal activity for each period. At week 0, 3, 7, 15 (end of running period), 16, 18, 22 and 30 (end of experiment), 5 rats of each group were sacrificed for measuring the bone relative density via micro-hardness measurement on the left tibia (60 points per tibia).

Bone density of running group increased asymptotically during the first 15 weeks. An abrupt decrease of density occurred when rats returned to sedentary state at week 15. The densification rate is ten times lower than the rate whereas bone formation delay (13 days) is greater than bone resorption delay (1 day). These delays were related to the delays of bone cells activities with mineralisation process in reaction to physical activities.