In recent years, machine learning (ML) and artificial neural networks (ANNs), a particular subset of ML, have been adopted by various areas of healthcare. A number of diagnostic and prognostic algorithms have been designed and implemented across a range of orthopaedic sub-specialties to date, with many positive results. However, the methodology of many of these studies is flawed, and few compare the use of ML with the current approach in clinical practice. Spinal surgery has advanced rapidly over the past three decades, particularly in the areas of implant technology, advanced surgical techniques, biologics, and enhanced recovery protocols. It is therefore regarded an innovative field. Inevitably, spinal surgeons will wish to incorporate ML into their practice should models prove effective in diagnostic or prognostic terms. The purpose of this article is to review published studies that describe the application of neural networks to spinal surgery and which actively compare ANN models to contemporary clinical standards allowing evaluation of their efficacy, accuracy, and relatability. It also explores some of the limitations of the technology, which act to constrain the widespread adoption of neural networks for diagnostic and prognostic use in spinal care. Finally, it describes the necessary considerations should institutions wish to incorporate ANNs into their practices. In doing so, the aim of this review is to provide a practical approach for spinal surgeons to understand the relevant aspects of neural networks. Cite this article:
The widespread dissemination of high-quality research facilitates keeping up to date with evidence-based practice, but the vast quantity can be overwhelming to physicians and surgeons. Information graphics, abbreviated to infographics, convey information using visualisations and images in an engaging manner. This format of presenting research format is preferable to 80% of clinicians when compared to text articles, and the long-term retention of information has been shown to be improve by a factor of 6.5 when methods were compared. Journal club was audited in our institution over 3 months. A multi-choice questionnaire was constructed weekly so as to test the attendees' recall of the research presented on a weekly basis. After five weeks, infographics were introduced, and the attendees' recall was assessed again on a weekly basis at the end of each journal club. The introduction of infographics to journal club saw improved test results from the journal club attendees. Not only was information retention improved, but the duration of journal club reduced following the intervention. Research can be disseminated efficiently using infographics in place of conventional journal club presentations. Satisfaction rates among clinicians, both with information retention and journal club duration, demonstrate the benefit of their use in teaching hospitals.
The internet has revolutionized the way we live our lives. Over 60% of people nationally now have access to the internet. Healthcare is not immune to this phenomenon. We aimed to assess level of access to the internet within our practice population and gauge the level of internet use by these patients and ascertain what characteristics define these individuals. A questionnaire based study. Patients attending a mixture of trauma and elective outpatient clinics in the public and private setting were invited to complete a self-designed questionnaire. Details collected included basic demographics, education level, number of clinic visits, history of surgery, previous clinic satisfaction, body area affected, whether or not they had internet access, health insurance and by what means had they researched their orthopedic complaint.Background
Method
Treatment of segmental bone loss remains a major challenge in orthopaedic surgery. This study evaluated the healing potential of a series of highly porous tissue engineering scaffolds with the current clinical gold standard. We compare healing of collagen-glycosaminoglycan (CG) and collagen micro-hydroxyapatite (CHA) scaffolds, with and without recombinant bone morphogenetic protein-2 (BMP2), with autogenous bone graft (ABG) in the healing of a 15mm rabbit radius defect, which were filled with either CG scaffold, CHA scaffold, CG-BMP2, CHA-BMP2 or ABG. Serial radiographs and micro-computed tomography (µCT) at six week radiographs demonstrated complete defect bridging with callus using CHA and CG-BMP2 while the CHA-BMP2 was already in an advanced state of healing with cortical remodeling. By sixteen weeks CHA, CG-BMP2 and ABG all had advanced healing with cortical remodeling while CHA-BMP2 had complete anatomic healing. Quantitative histomorphometry values demonstrated similarly high healing levels of healing in CHA, CG-BMP2 and ABG with highest overall values in the CHA-BMP2 group. Thus, treatment of a critical sized, weight bearing, rabbit radius defect with a CHA scaffold can result in full cortical bridging with medullary cavity development. In addition, a CHA-BMP2 combination can result in fully mature, anatomic healing. The use of an
Superficial – involves only the skin or subcutaneous tissue. Deep – involves the deep tissues (i.e. fascial and muscle layers). Organ / space – where part of the anatomy is manipulated during surgical procedure and within one year if an implant is in place. Between 2006 and 2008 the infection rates of the National Spinal Surgery Unit have been closely monitored as part of a multidisciplinary team approach led in large part by the Infection Control Team. A surveillance protocol was developed. They prospectively monitored every spinal surgery patient as part of a infection control data base. Biographical and medical history data were collated including diabetic status, prophylactic antibiotic use and surgical procedure. Information was collated and feedback on changes was examined by audit which was conducted regularly.
Horse riding is a popular competitive sport and leisure pursuit worldwide. Previous research has highlighted the unpredictable and independent nature of horses and high injury risk inherent in travelling at speeds of up to 65kph, 3-metres above the ground on an animal weighing between 450–500kg. In Ireland, jockeys register with the Turf Club as either professional or amateur with the remaining riders participating as unregistered. The aim of this study is to determine the national incidence of acute spinal cord injury (ASCI) and vertebral body injury (VBI) in horse riding in the Republic of Ireland, and to compare and contrast injury characteristics in registered and unregistered riders over an 11-year period (1995–2005). Chart review and structured telephone interview was performed in all cases to determine mechanism of injury, discipline, protective equipment, immediate management and whether the rider considered the injury could be prevented. American Spinal Injuries Association (ASIA) impairment score was used to classify outcome. Data for injuries sustained in competitive racing, for both registered and unregistered riders, was correlated with Irish Turf Club race records to ensure accuracy.
Background The non-motorised microscooter has become the urban transport of choice for children in Ireland. Recently, Josefson highlighted the rising trend of scooter-related injury in the US and predicted possible significant impacts in human and socioeconomic terms. Materials and Methods. A prospective study was undertaken of all referrals with scooter injuries to accident and emergency departments and fracture clinics in the first three months of the year. These cases were then reviewed at 6 months post injury Results: There were 151 microscooter injuries seen in the first 3 months of the year, Forming over 4% of all trauma seen over this period. Eighty nine of the patients (59%) were female, and the mean age at presentation was 8.5 years (range 3–15 years). The peak referral rates for January, February and March measured 48%, 29% and 23% respectively. A survey of attending paediatric outpatients over this period revealed that 75% of households possessed at least 1 scooter, and in those households with children aged between 4 and 14 years, the rate of micoscooter possession increased to 83%. Eighty four children suffered fractures and dislocations, 59 suffered soft tissue injuries, 8 had isolated head injuries. Upper limb fractures and dislocations were the most common injury (75 of 84 bone and joint injuries). Fracture of distal third of radius and ulna, was the most common single injury. upper limb fractures wer seen frequently. A high proportion of these had apex dorsal angulation with or without displacement (Smith deformity). Lower limb fractures were relatively rare. The pattern of soft tissue injuries and lacerations mostly affected the head and neck 25 (17%), the lower limb was involved in 19 (13%) and upper limb in 15 (10%) of patients. No major head injuries occurred. Only 5 patients had any adult supervision at the time of their injury. No children wore any formal protective clothing or apparatus. In the 84 patients who had suffered bony injury, at 6 months, 110 patients (73%) had
Introduction: Elucidation of the exact cause of adolescent idiopathic scoliosis (AIS) remains an elusive goal. The intervertebral disc is one of the many areas that have been investigated in an effort to find a cause for this condition. We hypothesize that a qualitative change in the orientation of collagen fibers in the annular layers of the disc could cause the deformity seen in AIS. This paper presents a mathematical model of such a change and how it could produce appropriate deforming forces. Hypothesis: In the normal disc the collagen fibers are obliquely orientated. Fibers in adjacent lamellae are orientated in opposing directions. This means that as forces are transmitted from a compressed nucleus to the annular fibers there is no net force tending to rotate one vertebra with respect to its neighbour. If there is a preponderance of fibers running in one direction as the nucleus is compressed there will be a net resultant force perpendicular to the long axis of the spine tending to produce an intervertebral rotation. This intervertebral rotation, applied to successive spinal segments will cause a scoliotic deformity. Model: The highly oriented structure of the AF suggests the utility of an explicit representation of the collagen fibres and their mechanical contribution to disc function. In our study we have considered two groups of fibres, representing the clockwise and counter clockwise fibres in the disc. The AF is considered as a continuum containing two populations of fibres assumes to be of equal density and uniform distribution within an isotropic material as originally described by Spencer. Nuclear compression as a result of growth was modelled as a tendency to produce increased intervertebral separation of spinal segments and examined whether the resultant transformation that leads to a scoliotic pattern of deformity. Based on anatomical data from literature the positions of the 12 nodes that represent the thoracic vertebrae are applied to the model. The three-dimensional location of each vertebral body is defined. We store the coordinates of thoracic vertebrae in a three-dimensional matrix. In the present study in order to involve the translation operation in our transformation, we have used the homogeneous transformation matrix or Denavit &
Hartenberg matrix. In the present model for the initial set of transformations the reference axis is chosen to be the lowest vertebral axis (T-12) and remains unchanged throughout the transformation. All elements of the spine above the reference axis are transformed (translated and rotated). After completion of this iteration and storing the values for the origin coordinate and vector values in the next level of the matrix, the next reference axis is chosen. For the second axis everything above the axis will be transformed in the same way with the current axis and the one preceding it remaining unchanged. Therefore for each transformation a new reference axis is taken and the transformations are applied to all vectors and origins above it leaving all elements preceding it unchanged by the transformation. Results: The first part of the model shows that rotational displacement increases linearly with changes in the fibre ratio. Rotational displacement on the other hand occurs independently of distraction of the vertebral bodies. When the rotational displacement is applied to a series of segments it produces alterations of curvature in the three planes. Specifically it produces a lateral curvature in the coronal plane and a hypokyphotic curvature in the saggital plane. The magnitude of these displacements varies with the imbalance in fibre ratio. Discussion: The proposed changes in annular fiber orientation have been modeled using accepted mathematical methods. These changes will produce an intervertebral rotation whose magnitude depends on the degree of fiber imbalance akin to that seen in AIS. When the displacements produced by this rotation being applied to a series of segments is modeled, it will produce a three dimensional deformity similar to that seen in AIS. Ongoing histological studies are being performed to see if the proposed imbalance can be identified in patients with AIS. Such a fiber orientation anomaly may be genetically determined by some fashion of directional sense gene and may be the aetiological basis for AIS.
In the absence of long-term outcome studies for the BHR these advantages remain theoretical. Furthermore, reports of good short and medium term results require corroboration at independent centres. This paper presents early results in a large series of patients in such an independent unit.
Average Harris hip score pre-operatively was 52 (range 25–65). This had improved to 89 at latest follow-up. All operations were performed via an extended posterior approach. No patients had neuro-vascular complications. Average hospital stay was 6.5 days; average transfusion requirement was 0.3 units. There were two spontaneous femoral neck fractures, both presenting with pain at approximately 2 months. Both were revised to conventionally stemmed femoral components with large metal heads (CorinTM). One patient presented with pain at 8 months and X-rays showed a fractured neck of femur. At revision, pus was found and diagnosis of infection was assumed. It was treated with a one-stage revision. 93 patients said they were very satisfied with their outcome and two were moderately satisfied. All patients who were more than six months post op (67 patients) had returned to their previous work (41 office work, 16 retailing, 10 farming). Twenty-six patients had returned to active leisure pursuits including running, golf, horse-riding and tennis.
Sixty patients were completely pain free at follow up. Seventeen patients complained of occasional mild pain after exercise but did not require analgesia. Eleven patients had moderate pain that occasionally required analgesia. Seven patients had severe causalgic type pain, all of who had had evidence of nerve injury at presentation. Only type C fractures with neurologic deficit at presentation had severe pain at follow up. Overall the incidence of pelvic pain, both anterior and posterior, was significantly higher in type C fractures. There were three non unions, all in type C fractures and one of these required surgery. There were fourteen mal unions, nine leg length discrepancies in type C fractures and five patients with a significant internal rotation deformity of greater than 15° in type B fractures.
The lymph drainage of the superficial tissues of the lower limb is via lymphatics that accompany the long saphenous vein and drain to the lower group of the superficial inguinal nodes. Drainage from the knee joint is to a popliteal node situated between the knee joint capsule and the popliteal artery. Efferents from this node ascend in close relation to the femoral vessels and drains to the deep inguinal nodes. We hypothesise that the differences in lymphatic drainage mean that palpable inguinal nodes are more likely with superficial infections than with septic arthritis. We reviewed the clinical findings in a group of patients with superficial or deep infections to test this theory.
In the superficial infection group 28 (56%) had pre-patellar bursitis and 23 (54%) cellulites. All were treated with antibiotics while eight of the bursitis group required incision and drainage. In the patients with superficial infection 32 (63%) had palpable inguinal lymphadenopathy while no patient with septic arthritis of the knee had palpably enlarged inguinal lymph nodes. This result is highly statistically significant (p<
0.01).
Little work has been done on gait initiation in children and there is no published data on gait initiation with cerebral palsy. The aim of this study was to examine the ground reaction forces and centre of pressure in normal children during gait initiation, to compare these to similar values in hemiplegic children and to try to identify differences between the two which may be diagnostic for hemiplegia. Patients and methods: Five normal and five hemiplegic children were studied. Kinematic and dynamic data were collected using a CodaTM motion analysis system and KestlerTM force plate. All subjects stood with one foot on and one foot off the force plate and walked off upon hearing an audible cue. Tests were repeated measuring right and left, normal and hemiplegic legs as both stance and swing legs. Ground reaction forces in the X,Y and Z axes, centre of pressure and kinematic data were collected and studied.
Medio-laterally the stance GRF tending to adduct falls initially and subsequently rises with a bimodal peak. The forces in the swing leg reciprocate these forces. 2) Hemiplegic children. The overall pattern seen when the normal leg is the stance leg are similar to those in normal children with certain specific variations in force development and magnitude. When the hemiplegic leg is the stance leg the overall patterns are again similar but considerably less smooth with characteristic changes indicative of neuro-muscular disturbance. The initial “adjusting” forces tend to be larger indicating the greater force required for control. Discussion: The pattern and relative magnitude of forces measured for normal children are identical to those previously reported for adults. This validates our study design and indicates that central programming for gait initiation develops early in life. It is therefore an early developmental skill and may be used as a diagnostic test in childhood. Significant variations are seen in cerebral palsy. Knowledge of these specific changes may allow earlier and more accurate diagnosis of cerebral palsy in children under investigation for movement disorders. Normal GRF patterns during gait initiations may provide early reassurance for parents of children suspected of having cerebral palsy.
We have carried out a blind, prospective study of 50 consecutive patients undergoing replacement arthroplasty of the hip using two different approaches. Clinical assessment, including the Harris hip score and a modified Trendelenberg test, and electrophysiological examination of the abductor muscles of the hip were undertaken before and three months after surgery. We found that 48% of patients had preoperative evidence of chronic injury to the superior gluteal nerve. Perioperative injury to the nerve occurred commonly with both approaches to the hip. We did not find a significant correlation between injury to the superior gluteal nerve and clinical problems.