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Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_21 | Pages 29 - 29
1 Apr 2013
Rose B Bowman N Edwards H Skyrme A
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Introduction

Hallux valgus surgical correction has a variable but significant risk of recurrence. Symptoms result from an iatrogenic first brachymetatarsia following the index surgical procedure. First metatarsal shortening has been shown to correlate with the onset of transfer metatarsalgia. We describe the use of the scarf osteotomy to both correct the recurrent deformity and lengthen the shortened first metatarsal.

Methods

36 lengthening scarf osteotomies were undertaken in 31 patients. Clinical (AOFAS and SF12 scores) and radiographic measures (IMA, HVA) were taken pre- and post-operatively. The maximum theoretical lengthening was 10mm, to prevent first MTP joint stiffness post-operatively. The actual lengthening was determined and measured intra-operatively.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 33 - 33
1 Jan 2013
Colegate-Stone T Colaco H Harper-Smith H Skyrme A Armitage A Rajaratnam S
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Study Aim

To assess the impact of two oral thromboprophylaxis agents against Clexane with regard to range of movement (ROM) following TKR with or without haemostasis following tourniquet release.

Methods & Results

Thromboprophylaxis choice following total knee replacement (TKR) has become of interest with the introduction of oral anticoagulants and support for these by NICE. Specific concerns with oral agents include a perceived elevated level of anti-coagulation and soft tissue complications.

The population (n=264) was subclassified into cohorts regarding thromboprophylaxis cover: Clexane, Rivaroxaban and Dabigatran. Each subgroup was subdivided into whether surgery was performed with or without haemostasis following tourniquet release.

This study demonstrates Clexane is associated with a better and earlier return of ROM post-operatively as compared to oral the thromboprophylaxis agents. This effect was more obvious when combined with haemostasis following early tourniquet release (p< 0.05). The oral thromboprophylaxis agents Rivaroxaban and Dabigatran had a relative negative effect on ROM as compared against Clexane. This was independent of whether the surgery was performed with or without haemostasis following tourniquet release. There was no different between the subgroups with repect to change of serum haemoglobin, symptomatic venous thromboembolism or rate of return to theatre.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 220 - 220
1 Jan 2013
Lidder S Desai A Dean H Sambrook M Skyrme A Armitage A Rajaratnam S
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Introduction

Osteochondral defects of the knee may occur following patella dislocation or following direct trauma or twisting injuries to the knee in adolescents. Often a diagnostic and therapeutic challenge, if these lesions are left, posttraumatic osteoarthritis may occur. This retrospective single centre study presents the short-term results following operative fixation of osteochondral fragments of the knee using Omnitech ® screws.

Method

All skeletally immature patients presenting with an osteochondral fracture of their femur or patella confirmed on xray and MRI were identified. Arthroscopic evaluation of the osteochondral defect was performed followed by open reduction and internal fixation of the osteochondral fragment using Omnitech ® screws. A standard postoperative rehabilitation protocol was followed. Patients were evaluated at follow-up using a Knee Injury and Osteoarthritis Outcome Score (KOOS).


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 104 - 104
1 Jul 2012
Hoare C Harper-Smith H Ashman O Skyrme A Rajaratnam S Armitage A
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Introduction

This study investigates the effect of Rivaroxaban (Bayer HealthCare) on early post-operative stiffness in primary total knee replacement.

Methods

The anticoagulant of choice for total knee arthroplasty in our Department was changed from Enoxaparin to Rivaroxaban in September 2009. We reviewed a consecutive, multi-surgeon, multi-implant series of primary total knee replacements for a 6 month period prior to (group A) and after (group B) the treatment change. All patients were reviewed by an independent Clinical Specialist Physiotherapist at 6 weeks post-surgery, where the range of movement was recorded prospectively using a goniometer. A stiff knee replacement was defined as one with 15 degrees of extension deficit or flexion to less than 75 degrees at 6 week follow up. All data was analysed on an intention to treat basis.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 60 - 60
1 Jul 2012
Colaço H Davidson J Pekicten B Ahmed S Skyrme A Armitage A Rajaratnam S
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Purpose

This study investigates the effect of early tourniquet release on range of flexion following total knee replacement, and the influence of anticoagulation with Rivaroxaban and Clexane (Enoxaparin).

Method

78 patients were included in the study, who underwent unilateral primary total knee replacement (TKR) in our department under the care of two specialist knee surgeons over a 12 month period. 27 patients underwent TKR with early release of the tourniquet and haemostasis, prior to closure of quadriceps layer: 22 were anticoagulated with Rivaroxaban (GROUP ER), 15 with the low molecular weight heparin Clexane (GROUP EC). Over the same time period, 41 patients TKR with late release of the tourniquet, following closure and bandaging: 13 were anticoagulated with Rivaroxaban (GROUP LR), 28 with Clexane (GROUP LC). A standardised operative technique was employed, and all patients received an AGC (Biomet) PCL-retaining prostheses. Outcome was assessed with range of flexion at 12 weeks postoperatively.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 328 - 328
1 Jul 2008
Papavasiliou AV Isaac DL Marimuthu R Nurboja B Skyrme A Armitage A
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Objective: To assess the possible effect of intra-articular steroid injections to future TKA.

Materials-Method: We retrospectively studied all 231 patients who underwent AGC (Biomet) TKR in our hospital from February 2002 to October 2004. Twenty notes were not available in medical records and were excluded from the study. Other exclusion criteria were previous surgery (other than knee arthroscopy) on the affected site, a diagnosis of inflammatory arthritis, immunosu-pressed patients, a previous history of infection around the knee, smoking, diabetic patients. Applying these criteria we excluded a further sixty-seven patients.

The remaining 144 patients were separated in to two groups. Group I (n=54) consisted of those patients that received one or more recorded I/A steroid injections in their operated knee in an orthopaedic clinic, rheumatology clinic or general practice setting prior to surgery. Group II (n=90) consisted of those patients with no record of receiving an I/A steroid injection prior to surgery.

Results: We found that all the deep infections (3) were from Group I and had received an I/A steroid injection up to 11 months prior to surgery. The incidence of superficial infection was not significantly different from the control group (Group II).

In addition to those patients with confirmed deep infections, five patients underwent post-operative investigations for suspected deep infection, due to symptoms of persistent swelling or pain. All had received an I/A steroid injection pre-operatively.

The length of time between injection and subsequent post-operative infection leads us to speculate that the steroid agent might not fully dissolve, becoming trapped within the soft tissues or cystic areas of degeneration in the knee joint. Such steroids may become re-activated during operation, leading to catastrophic results. Indeed, there is experimental evidence to suggest an increased risk of infection with the intra-operative administration of steroids.

Conclusion: We conclude that the decision to administer intra-articular steroids to a patient who may be a candidate for knee replacement surgery should not be taken lightly because of a risk of post operative deep infection.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 3 | Pages 321 - 323
1 Mar 2006
Papavasiliou AV Isaac DL Marimuthu R Skyrme A Armitage A

We reviewed 231 patients who had undergone total knee replacement with an AGC (Biomet) implant over a period of 2.5 years. After applying exclusion criteria and with some loss to follow-up, there were 144 patients available for study. These were divided into two groups; those who had received intra-articular steroid in the 11 months before surgery and those who had not.

There were three deep infections, all of which occurred in patients who had received a steroid injection. The incidence of superficial infection was not significantly different in the two groups. Five patients had undergone investigation for suspected deep infection because of persistent swelling or pain and all of these had received an intra-articular injection pre-operatively. We conclude that the decision to administer intra-articular steroids to a patient who may be a candidate for total knee replacement should not be taken lightly because of a risk of post-operative deep infection.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 351 - 351
1 Sep 2005
Zicat B Vedi V Skyrme A Chia M Walter W Walter W
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Introduction and Aims: Polyethylene wear and associated osteolysis is a major factor limiting arthroplasty longevity. The Duration process has the theoretical advantage of reducing wear. Our aim was to evaluate the wear rate of standard and Duration polyethylene using either metal or zirconia ceramic heads in the Anatomique Benoist Girard II hip system.

Method: Of 510 patients, 258 had appropriate radiographs for wear measurement. There were five bearing-couple groups. Group 1, 73 patients: metal (cobalt chrome) head on standard polyethylene; group 2, 73 patients: metal head on Duration polyethylene; group 3, 21 patients: (HIPed) zirconia ceramic head on standard polyethylene; group 4, 63 patients: HIPed zirconia head on Duration polyethylene; and group 5, 28 patients: non-HIPed zirconia head on standard polyethylene. All patients had 28mm heads. Sequential radiographs – at least one year after surgery and at least two years apart thereafter – were digitally scanned and images were analysed using computer software.

Results: Group 1: metal on standard polyethylene (n=73) – mean linear wear rate of 0.138 mm/yr (range 0.023–0.462 mm/yr). Group 2: metal on Duration polyethylene (n=73) – mean linear wear rate of 0.106 mm/yr (range 0.067–0.405 mm/yr). Group 3: HIPed zirconia heads on standard polyethylene (n=21) – mean linear wear rate of 0.124 mm/yr (range 0.037–0.225 mm/yr). Group 4: HIPed zirconia heads on Duration polyethylene (n=63) – mean linear wear rate of 0.120 mm/yr (range 0.001–0.427 mm/yr). Group 5: non-HIPed zirconia heads on standard polyethylene (n=28) – mean linear wear rate of 0.119 mm/yr (range 0.044–0.0330 mm/yr). Comparison of linear wear rates of standard (group 1) and Duration polyethylene (group 2) bearings with metal heads revealed a difference of statistical significance (p=0.0083), with lower annual wear rates with Duration polyethylene. Further comparison between these two groups revealed a male preponderance in the Duration group (p=0.000001). There was also a statistically significant difference in body weight between these groups, with the Duration group being heavier by a mean of 5.1 kilograms (p=0.05). There was no significant difference in wear rates between standard and Duration polyethylene bearings with HIPed zirconia heads. There was no statistically significant difference in age in our patient groups.

Conclusion: Duration polyethylene has lower linear wear rates when coupled with a cobalt chrome head. This is despite a male preponderance and higher body weight. Wear rates between standard and Duration polyethylene bearings coupled with zirconia heads were not statistically different.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 467 - 467
1 Apr 2004
Skyrme A Walter W Zicat B
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Introduction This study was performed to evaluate the wear rates of Zirconia ceramic heads manufactured prior to the introduction of hot isostatic pressing, on a modular cementless polyethylene cup, and to compare this with the wear rate of a cobalt chrome head coupled with the same cup.

Methods Radiological analysis of 281 primary uncemented ABG total hip arthroplasties performed between 1991 and 1994 was carried out. Patients were divided into three groups: 203 patients with 28 mm zirconia head/polyethylene bearings, 47 patients with 32 mm zirconia ceramic head/polyethylene bearings, 31 patients with 28 mm cobalt chrome head/polyethylene bearings. Wear analysis was performed using the Martel software after digitising radiographs on a flatbed scanner. Initial radiographs were at a minimum of one year to exclude bedding in, and follow-up radiographs a minimum of two years later. Mean follow-up was 6.5 years.

Results The mean linear wear rate of the groups following age and gender matching: for 28 mm Zirconia heads 0.22 mm/yr, for 32 mm Zirconia heads 0.20 mm/yr and for 28 mm metal heads 0.14 mm/yr (p< 0.05). The patients with Zirconia heads had higher rates of osteolysis and revision than those with cobalt chrome heads.

Conclusions The reason for this increased wear rate of Zirconia on polyethylene may well be the transformation of the tetragonal stable phase of the Zirconia to the monolithic unstable phase on the surface of the material. This transformation at grain boundaries on the surface results in ceramic grain “pull-out” by the sliding action of the head against the polyethylene cup. This phenomenon may well occur as a result of the Zirconia processing; the ceramic studied was produced prior to hot isostatic pressing, which produces an inherently more stable ceramic i.e. a higher percentage of the tetragonal phase.

In relation to the conduct of this study, one or more of the authors is in receipt of a research grant from a non-commercial source.