Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVII | Pages 39 - 39
1 Jun 2012
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The cause of adolescent idiopathic scoliosis (AIS) is still not known. Although several candidate gene studies and linkage analyses have been done, no causal relationship has yet been established. To our knowledge, we report the first case-control based genome-wide association study (GWAS) for this trait. The study was undertaken in a set of 196 cases with a specific AIS phenotype (based on Lenke's classification) in southern China, and in 401 controls without radiological evidence of scoliosis.Introduction
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