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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_3 | Pages 2 - 2
1 Apr 2019
Mannan A Walmsley K Mandalia V Schranz P
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Background

The meniscal deficient knee often exists in the setting of associated pathology including instability, malalignment and chondral injury. Meniscal allograft transplantation (MAT) is established to be a reliable option in restoring function and treating symptoms. The aim of this study was to establish the role of MAT as part of a staged approach to treatment of the previously menisectomised knee.

Methods

This prospective study included all patients that underwent arthroscopic MAT at our institution between 2010 to 2017. Fresh frozen allograft was utilised using a soft tissue fixation technique. Further data was collected for index surgical procedures before and after MAT. Data for pre and post-operative Knee Injury and osteoarthritis outcome scores (KOOS), Tegner scores, graft survival, reoperation rates, patient satisfaction and MRI extrusion measurements were collected and details of any further surgical intervention and / or complications also documented.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_10 | Pages 8 - 8
1 Oct 2015
Ahmad R Calciu M Jayasekera N Schranz P Mandalia V
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Patients with recurrent patella instability, who have an abnormal patellofemoral alignment (patella height or tibial tubercle-trochlear groove (TTTG) distance), benefit from tibial tubercle transfer along with medial patellofemoral ligament (MPFL) reconstruction. Between July 2008 and April 2013, 18 patients (21 knees) with recurrent patellar instability underwent combined MPFL reconstruction and tibial tubercle transfer. All patients had abnormal patellofemoral alignment in addition to MPFL insufficiency. 15 patients (16 knees) with a mean age of 24 years (16–41) had a mean follow up of 26 months (6–55). We assessed the outcome using KOOS, KUJALA, activity level and patient satisfaction scores. All patients had a stable patella. There was a significant improvement in outcome scores in 12 out of 15 patients. At final follow up KOOS score had improved from 68.25(44 to 93.9) to 77.05(48.8 to 96.4) and KUJALA score had improved from 63.3(41–88) to 78.06 (45 to 99). 9 patients showed excellent results and achieved at least a pre-injury level of activity. 4 of these had activity level better then preoperative level. 6 patients had a lower activity level than pre-injury (1 – ongoing physiotherapy, 1 – because of lack of confidence, and 4 – Life style modification). 14 patients were satisfied and happy to recommend this procedure. There were 3 postop complications, with 2 cases of stiffness and 1 case of non-union of the tibial tuberosity. Our prospective study has shown that restoration of tibial tubercle-trochlear groove index, Patella height and Medial Patellofemoral Ligament reconstruction yields good results in carefully selected patients.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_6 | Pages 19 - 19
1 May 2015
Woodacre T Evans J Pavlou G Schranz P Hockings M Toms A
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Limited literature exists providing comprehensive assessment of complications following opening wedge high tibial osteotomy (OWHTO). We performed a retrospective study of local patients who underwent OWHTO for isolated medial compartment knee osteoarthritis from 1997–2013.

One hundred and fifteen patients met inclusion criteria. Mean follow-up = 8.4years. Mean age = 47 (range 32–62). Mean BMI = 29.1 (range 20.3–40.2). Implants used included Tomofix (72%), Puddu plate (21%) and Orthofix (7%) (no significant differences in age/ sex/ BMI). Wedge defects were filled with autologous graft (30%), Chronos (35%) or left empty (35%).

Five year survival rate (conversion to arthroplasty) = 80%. Overall complication rate = 31%. 25% of patients suffered 36 complications including minor wound infections (9.6%), major wound infections (3.5%), metalwork irritation necessitating plate removal (7%), non-union requiring revision (4.3%), vascular injury (1.7%), compartment syndrome (0.9%), and other minor complications (4%). No thromboembolic complications were observed.

A higher BMI (mean 34.2) was apparent in those patients suffering complications than those not (mean 26.9). No significant differences existed in complication rates relative to implant type, type of bone graft used or patient age at surgery.

Complications following OWHTO appear higher than previously reported in the literature; serious complications appear rare.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_19 | Pages 11 - 11
1 Apr 2013
Mandalia V Kassam A Schranz P
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Introduction

Anatomical reconstruction of the Anterior Cruciate Ligament (ACL) reconstruction has been shown to be desirable and improve patient outcome. The posterior border of the anterior horn of the lateral meniscus (AHLM) is an easily identifiable arthroscopic landmark, which could guide anatomic tibial tunnel position in the sagital plane. The aim of the study was to establish the relationship between the posterior border of AHLM and the centre of the ACL foot print to facilitate anatomical tibial tunnel placement.

Materials/Methods

We analysed 100 knee MRI scans where there was no ACL or lateral meniscal injury. We measured the distance between the posterior border of the AHLM and the midpoint of the tibial ACL footprint in the sagital plane. The measurements were repeated 2 weeks later for intra-observer reliability.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XVI | Pages 23 - 23
1 Apr 2012
Mandalia V William C Brown K Schranz P Silver D Redfern A Powell R
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The aim of this prospective study was to determine the prevalence of bone marrow oedema (BME) in asymptomatic knees of athletes and to investigate the factors associated with appearance of BME in this group.

A total of 25 asymptomatic athletes who competed at an international, national or county level during their most recent sport season were recruited in this study and had MRI scan of both knees (n=50). MRI scans were reported independently by two experienced musculoskeletal radiologists. Statistical analysis included Cohen's kappa test to identify inter-observer agreement for MRI diagnosis of bone marrow oedema and multiple logistic regression model to identify the factors associated with BME on MRI scan.

There was very good agreement between radiologists for diagnosis of BME (Kappa = 0.896). Seven participants (28%) were found to have BME. Six of the participants had BME in unilateral knees and one participant had BME in bilateral knees. The commonest location of BME was medial femoral condyle (62.5%) The amount of time spent in preseason training (34-38 weeks) was significantly associated with appearance of BME (P=0.048)

BME seems to be common in asymptomatic athletes and one should realize that this finding might not be related to the clinical complaints of the patients. The results of the present study show that there is a training effect associated with BME. Knowing what is a ‘normal’ or ‘abnormal’ scan is important for a competitive athlete, as erroneously diagnosing BME as the underlying cause of athletes' symptoms could lead to decreased playing time or inappropriate therapy.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 47 - 47
1 Jan 2011
Matthews J Schranz P
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Purpose: Patellar instability is a common clinical problem affecting a young, active population. A large number of procedures have been described to treat patellar instability. We present the clinical results in a case series of 25 medial patellofemoral ligament reconstructions in 21 patients with up to 30 months follow-up (mean 7.3 months).

Methods: Reconstruction was performed using either the gracilis tendon (6 cases) or semitendinosus tendon (19 cases) autograft. At follow-up the Tegner activity scores, objective knee function, complications and reoperations were assessed.

Results: No patella re-dislocations were observed. Five patients (20%) required a manipulation under anaesthetic but subsequently regained a satisfactory range of motion. Two patients (8%) had post operative complications. One patient developed a post operative infection which required a washout and one patient developed a neuroma related to the hamstring harvest site which was excised. Both subsequently returned to work with a full range of motion. No patients sustained a patellar fracture.

Conclusions: Medial patellofemoral reconstruction with both gracilis and semitendinosus tendon graft using a longitudinal tunnel technique provided good postoperative patellar stability restoring the primary soft tissue restraint to pathological lateral patellar displacement.

Level of evidence: Level IV, therapeutic case series.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 400 - 400
1 Sep 2009
Darmanis S Schranz P Toms A Eyres K
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There are many reports in the literature about the benefits of computer-aided surgery with regards to improved limb alignment, reduced blood loss and embolic events but surgeons remain sceptical about its routine use because of availability, cost and time implications. To maximise these benefits and overcome the distractions, a modified navigation technique has been developed after evaluation of the standard measurements.

The true varus/valgus angle of the distal femoral cut achieved with navigation is unknown but represents presumed accurate alignment with regards to the mechanical axis through the femoral head. With placement of the femoral tracker in the medial supracondylar region clear of the intramedullary canal, the navigated cut was correlated with the cut placement determined with the standard intramedullary jig in 10 patients undergoing knee replacement. In addition, jigged femoral rotation was checked with the tracker placement. Tibial slope, varus/valgus angle and rotation were determined using surgeon placement of an external alignment jig and confirmed with tracker placement.

The navigated distal femoral cut ranged from +3 degrees to −2 degrees when measured against the distal cutting block stabilised over an intramedullary rod. The femoral rotation was within 1 degree of the trans-epicondylar line as outlined by navigation when a 3 degree externally rotated jig was used. All of the tibial measurements were within 0.5 degrees of the navigated planned positions.

The femoral cuts are presumed to be accurately determined with navigation as judged from long-leg alignment x-rays but this study highlights the potential error if a fixed valgus cut angle with alignment jigs is used. Tibial preparation, however, was accurately predicted by the surgeon using a traditional external alignment jig. Bone preparation time was reduced to 4 minutes (modified technique) compared to 12 minutes (full navigation, p< 0.05).

With this information, computer-aided navigation is now routinely used to determine the distal femoral cut only and an external alignment jig is used for tibial preparation without navigation. The reduction in blood loss and embolic events and improved limb alignment is now achieved with a reduction in preparation time over full navigated techniques. Use of the pinless surface mounted femoral jig alone highlights these advantages further.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 502 - 502
1 Sep 2009
Matthews J Schranz P
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Patellar instability is a common clinical problem affecting a young, active population. A large number of procedures have been described to treat patellar instability. We present the clinical results in a case series of 25 medial patellofemoral ligament reconstructions in 21 patients with up to 30 months follow-up (mean 7.3 months).

Reconstruction was performed using either the gracilis tendon (6 cases) or semitendinosus tendon (19 cases) autograft. At follow-up the Tegner activity scores, objective knee function, complications and reoperations were assessed.

No patella re-dislocations were observed. Five patients (20%) required a manipulation under anaesthetic but subsequently regained a satisfactory range of motion. Two patients (8%) had post operative complications. One patient developed a post operative infection which required a washout and one patient developed a neuroma related to the hamstring harvest site which was excised. Both subsequently returned to work with a full range of motion.

Medial patellofemoral reconstruction with both gracilis and semitendinosus tendon graft provided good postoperative patellar stability restoring the primary soft tissue restraint to pathological lateral patellar displacement.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 87 - 87
1 Mar 2009
Biau D Tournoux C Katsahian S Schranz P Nizard R
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Background From individual randomized studies it is unclear which of patellar (PT) tendon or hamstring (HS) tendon grafts yields the best functional results after ACL reconstruction. Therefore, we performed a meta-analysis to provide quantitative data to compare PT (control group) to HS (treatment group) grafts after ACL reconstruction with regards to knee function.

Methods We searched computerized databases for randomized controlled trials reporting one of the following outcome related to function: final overall International Knee Documentation Committee (IKDC) score and return to pre-injury level of activity. Studies were abstracted independently by two reviewers. Random effect models were used to pool the data.

Results Fourteen trials (1263 patients) met the inclusion criteria. There was no difference in final overall IKDC and in the number of patients returning to full activity after PT and HS graft reconstruction. Relative risk was 0.90 for final overall IKDC score class A in favor of PT grafts (not significant, P=0.13), and 0.94 for return to pre-injury level of activity in favor of PT grafts (not significant, P=0.28). Quantitative interaction tests on the effect of treatment based on study quality, randomization status, number of strands used, and length of follow-up were not significant. At last follow-up, only 41% and 33% of PT and HS graft reconstructed patients were respectively reported as normal using the final overall IKDC.

Conclusion There was no difference in the final overall IKDC and in the number of patients returning to full activity after HS tendon graft and PT graft reconstructions. It should be emphasized that more than 60% of the patients will not make full recovery after their reconstruction and patients should be informed accordingly.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 3 | Pages 265 - 271
1 Mar 2008
Mandalia V Eyres K Schranz P Toms AD

Evaluation of patients with painful total knee replacement requires a thorough clinical examination and relevant investigations in order to reach a diagnosis. Awareness of the common and uncommon problems leading to painful total knee replacement is useful in the diagnostic approach. This review article aims to act as a guide to the evaluation of patients with painful total knee replacement.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 2 - 2
1 Mar 2008
Talbot N Rosewarne A Sharpe I Schranz P
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To evaluate if adequate restoration of the medial cortical buttress reduces the high reported incidence of mechanical complications when using the AO unreamed femoral nail with spiral blade (UFN-SB) in the management of subtrochanteric femoral fractures. The clinical notes and radiographs of sixty-five patients treated with the UFN-SB between November 1996 and February 1999 were retrospectively reviewed. Twenty-eight of these fractures were subtrochanteric. Mean patient age was seventy-five and thirteen patients had metastatic disease. At the time of review the patients or their doctor were contacted by telephone to establish accurately the associated morbidity and mortality. Follow up information was obtained for every patient. Post-operative radiographs were assessed for accuracy of fracture reduction.

The medial cortical buttress was adequately restored in every case. This required open fracture reduction in eleven patients and cerclage wires augmented the reduction in eight of these cases. Open reduction did not significantly increase time to fracture union or transfusion requirement. Every surviving patient was fully weight bearing within three months. One patient required a second operation for spiral blade migration but there were no implant breakages or other mechanical complications after a mean follow-up of thirty-seven months.

Conclusion: Adequate restoration of the medial cortical buttress allows the UFN-SB to function as a load-sharing device and achieves reliable skeletal stability in these potentially unstable fractures that typically occur in osteoporotic or pathological bone.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 128 - 129
1 Jul 2002
Sharpe I Talbot N Schranz P
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We present a retrospective clinical and radiological review to assess the use of the AO unreamed femoral nail and spiral blade in the treatment of subtrochanteric fractures. Treatment of the subtrochanteric fracture remains a challenge. A combination of high stress concentration, poor cortical bone quality and comminution leads to a high incidence of problems. The abovementioned implant has been recommended for use in such fractures. However, several authors have reported mechanical failure and spiral blade migration. We have used the unreamed femoral nail since 1996 in 65 femoral fractures, and of these 32 were subtrochanteric fractures. A retrospective clinical and radiological study was undertaken to assess the use of the implant.

Clinical notes and radiographs were obtained for patients with subtrochanteric fractures treated with the AO unreamed femoral nail from November 1996 to November 1999. Fracture pattern was classified according to Seinsheimer. Assessments were made of callus formation and fracture healing. Any complication or implant failure was noted.

Thirty-two patients required an unreamed femoral nail. There were 20 females and 12 males, with an average age of 75 years. There were 16 fractures due to a fall, 15 pathological fractures, and one due to a car accident. Classification was: Type I: 6; Type II: 13; Type III: 6; Type IV: 3; Type V: 1. Mean follow-up was five months (range 3 to 18). Eight deaths occurred within one month. There were two pain-free non-unions, one revision with bone graft for non-union, and one spiral blade back out. No breakage of implants occurred.

We found that this implant provides stable fixation in these difficult fractures if adequate reduction is obtained. We have not experienced the implant failures reported in other series. We recommend the use of the implant, especially in those patients who are elderly or have pathological fractures.