Identification of the causal pathogen is crucial in the management of periprosthetic joint infection (PJI) of the hip. Unfortunately, it was often difficult and negative culture could be a common findings. This situation made the treatment of PJI of the hip became more challenging. The negative culture finding resulted in a doubtful diagnosis of infection, and poses difficulty in choosing the appropriate antibiotics. Here we compared the treatment outcome of two-stage revision arthroplasty for culture-negative versus culture-positive PJI of the hip. We retrospectively reviewed patients who received two-stage revision for PJI of the hip between January 2010 to June 2015. All patients was planned to received articulated antibiotic cement-spacer as the first stage and revision total hip arthroplasty (THA) as the second stage of the procedure. Out of total 94 patients, 10 patients was loss to follow-up and excluded from the study. We devided the rest of 84 patients into two groups: culture-negative group (n: 27) and culture-positive group (n: 57). We compared all relevant medical records and the treatment outcome between the two groups.Aim
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