There are no published studies investigating predictive values of psychological distress on effectiveness of epidural injection. To evaluate response to epidural injection (EI) in patients with chronic lower back pain (CLBP) with and without psychological distress.Background
Aims
In selected patients in-cement revision of the total hip arthroplasty components is an attractive option. Recommended roughening of the primary mantle surface remains controversial. Aim of the study was to investigate the influence of the cement surface roughening on the strength of bilaminar cement interface. Flat, laboratory model of bilaminar cement interface was used. Prior to its creation, modeled primary mantle surface was machined to the roughness of either smooth surface observed after removal of a highly polished stem (Ra=200nm) or that following roughening (Ra=5μm). Two viscosities of interfering fluids (water and bone marrow) were also used. 6 variants (smooth or rough, both stained with water, bone marrow or with no fluid) with 7 repeats were exposed to single shear to failure. No significant difference in resistance to shear was observed between the groups with dry smooth (16.82MPa) and rough surfaces (16.96MPa), and those stained with large volume of low viscosity fluid. In the presence of water, roughening did not significantly influence the interface (smooth – 17.04MPa and rough – 16.25MPa respectively). In the smooth variant with large volume of viscous fluid, ultimate stress value dropped to 5.53MPa, and 9.87MPa in the roughened group with the same amount of viscous fluid (p<
0.05). Extra roughening may offer some benefit when performing in-cement revision in the presence of large volume of viscous fluid only though in-cement revision would not be then recommended. In the presence of low viscosity fluids (blood, irrigation fluid) benefit of roughening is dubious.
During hip revision removal of old cement mantle is a major problem. In cases of satisfactory bond between cement mantle and the underlying bone, cementing the revision stem into the old mantle is regarded as a highly attractive option. The aim was the analysis of the shearing strength of the interface between two layers of poly-methylmethacrylate cement in the presence of fluid. A laboratory, two-dimensional model of the interface was used. Effect of different viscosity fluids and volumes on its strength was checked. 6 variants (control monoblock, dry surface, surface stained with small or large volume of water or highly viscous fluid) containing 7 repeats were exposed to a single shearing stress to failure. Large volume of viscous fluid prevented bonding completely in two cases and significantly weakened the other samples showing mean failure stress of 5.53 MPa. This was significantly lower compared with control monoblock (19.8MPa), dry surface variant (16.9MPa) and the stain with small amount high viscosity fluid (16.01MPa). Interestingly, presence of a large volume of low viscosity fluid did not significantly reduce resistance to shear stress (17.05MPa). In all but large volume of viscous fluid variants, the failure occurred away from the interface between two cement layers. Large amount of viscous fluid weakened significantly this interface. If such a viscous fluid could be eliminated by copious water irrigation it is likely that strength of the cement-cement bond will be maintained. Our observations suggest that cement-in-cement technique seems to be biomechanically acceptable
The mechanical performance of the cement-in-cement interface in revision surgery has not been fully investigated. The quantitative effect posed by interstitial fluids and roughening of the primary mantle remains unclear. We have analysed the strength of the bilaminar cement-bone interface after exposure of the surface of the primary mantle to roughening and fluid interference. The end surfaces of cylindrical blocks of cement were machined smooth (Ra = 200 nm) or rough (Ra = 5 μm) and exposed to either different volumes of water and carboxymethylcellulose (a bone-marrow equivalent) or left dry. Secondary blocks were cast against the modelled surface. Monoblocks of cement were used as a control group. The porosity of the samples was investigated using micro-CT. Samples were exposed to a single shearing force to failure. The mean failure load of the monoblock control was 5.63 kN (95% confidence interval (CI) 5.17 to 6.08) with an estimated shear strength of 36 MPa. When small volumes of any fluid or large volumes were used, the respective values fell between 4.66 kN and 4.84 kN with no significant difference irrespective of roughening (p >
0.05). Large volumes of carboxymethylcellulose significantly weakened the interface. Roughening in this group significantly increased the strength with failure loads of 2.80 kN (95% CI 2.37 to 3.21) compared with 0.86 kN (95% CI 0.43 to 1.27) in the smooth variant. Roughening of the primary mantle may not therefore be as crucial as has been previously thought in clinically relevant circumstances.
6 variants (control monoblock, dry surface, surface stained with small or large volume of water or highly viscous fluid) containing 7 repeats were exposed to a single shearing stress to failure at the speed of 1mm/min (Autograph AGS, Shimadzu, Japan). Results were analyzed using 1-way ANOVA with post-hoc analysis (equal N HSD) and power calculations.
Similar relations were observed when strain at failure and toughness were analyzed.
Comparison of the safety and efficacy of Bilateral Simultaneous Total Hip Arthroplasty (BSTHA) with that of staged (SgTHA) and unilateral (UTHA) was conducted using DerSimonian–Laird heterogeneity meta-analysis. Twenty three citations were eligible for inclusion. A total of 2063 BSTHA patients were identified. Meta-analysis of homogenous data revealed that there were no statistically significant differences between rates of thromboembolic events (p=0.268 and p=0.356) and dislocation (p=0.877) when comparing SgTHA or UTHA versus BSTHA procedures. Systematic analysis of heterogenous data demonstrated that mean length of stay was shorter in BSTHA as compared to SgTHA and UTHA procedure, blood loss was lower in BSTHA in all studies except one, whilst the surgical time was not different between groups. BSTHA was also found to be economically and functionally efficacious.