The efficacy of tranexamic acid (TXA) to reduce blood loss in various surgical procedures has been proven. However, there is little data about the effect of TXA on blood loss, rate of blood transfusion and thromboembolic events during periacetabular osteotomy (PAO). The reduction of blood loss during PAO promotes postoperative mobilization and reduces the risk of complications, associated with blood transfusions. The aim of the following study was to determine, if TXA can reduce both blood loss and the rate of blood transfusions. In addition we analyzed whether TXA was associated with an increased risk of thromboembolic events. A consecutive series of 96 PAO procedures was reviewed to compare the groups immediately prior to and following the routine implementation of TXA. The TXA group received a continuous infusion of TXA with a rate of 10mg/kg/h. The outcome was blood transfusion rate, total blood loss, length of hospital stay, and thromboembolic events.INTRODUCTION
METHODS
