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The Bone & Joint Journal
Vol. 102-B, Issue 6 | Pages 655 - 657
1 Jun 2020
Minhas Z Ganau M Thakar C Reynolds J Rothenfluh D Bojanic S Grannum S Chaudhary BR Pyrovolou N Sikander M Bowden G Patel UJ Nnadi C


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXI | Pages 17 - 17
1 Jul 2012
Pyrovolou N MacDonald JW Fairbank J Nnadi C
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STUDY DESIGN

Retrospective study of 8 children treated with vertical expandable prosthetic titanium rib (VEPTR) for correction of early onset spinal scoliotic deformities.

METHODS

8 children with progressive scoliosis due to a variety of conditions, 6 congenital (2 Goldenhar syndrome, 2 VACTERL syndrome, 2 congenital thoracic abnormalities), 1 spondyloepiphyseal dysplasia, 1 early onset of scoliosis, underwent the index procedure and subsequent lengthening procedures at 6 months intervals (1 patient had 11 lengthening procedures).

Mean age was 4 years (2-6 years) and mean follow up 3.8 years (2-6 years). Mean preoperative Cobb angle was 64,8° (51-108) and mean postoperative angle 40° (31-50)


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXI | Pages 16 - 16
1 Jul 2012
Pyrovolou N Reynolds J Rogers R Fairbank J
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STUDY DESIGN

Retrospective review of outcome of submuscular rod placement without apical fusion for the treatment of scoliotic deformities in children with severe co morbidities (ASA IV).

METHODS

6 children with progressive scoliosis (2 severe cerebral palsy, 2 congenital cyanotic heart disease, 1 Worster Drought syndrome, 1 Leigh's disease), underwent a serial and limited exposure of the lower and then the upper end of the spine, and insertion of pedicle screws, hooks and clamps. Two submuscularly rods were connected and distracted.

Mean age was 13 years old, the mean preoperatively Cobb angle was 87° and the mean postoperatively Cobb angle was 62°. The mean operation time was 120 min and the peri-operative blood loss was 410 ml. Mean follow up is 15 months.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVI | Pages 71 - 71
1 Jun 2012
Pyrovolou N Rout R Nnadi C
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Aim

To evaluate the effect of corrective surgery for adolescent idiopathic scoliosis on pelvic morphology.

Introduction

Pelvic incidence increases linearly with age during childhood and adolescence before stabilising in adulthood. Most scoliosis surgery occurs before adulthood. We tested the hypothesis that during growth, scoliosis surgery alters the normal linear relationship between pelvic incidence and age.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XIII | Pages 9 - 9
1 Apr 2012
Pande R Dhir J Pyrovolou N Ahuja S
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Purpose

To evaluate Radiological changes in the lumbosacral spine after insertion of Wallis Ligament for Foraminal Stenosis.

Methods and Results

Thirty two Levels in Twenty Six patients were followed up with standardised radiographs after insertion of Wallis Ligaments for Foraminal Stenosis. Wallis ligaments as a top-off or those with prolapsed discs were not included. The Radiological parameters compared were Anterior and Posterior Disc height, Foraminal height and width, The inter-vertebral angle (IVA), Lumbar lordosis and Scoliosis if any. The presence of slips and their progression post-op was noted, as was bony lysis if any.

There were ten males with thirteen levels and sixteen females with nineteen levels in the study. Eighteen levels (56.25%) were L4/L5, ten (31.25%) were L5/S1 and 4 (12.5%)were L3/L4. The average age in the series was 59.6 years (Range 37 – 89 yrs). Average follow up was 9.5 months (Range 2 to 36). The Average increase in Anterior disc height was 1.89 mm (+/−1.39), the posterior disc height increased by an average 1.09 mm (+/−1.14). Foraminal height increased by an average 3.85 mm (+/− 2.72), while foraminal width increased by 2.14 mm (+/− 1.38). The IVA increased in 16 and reduced in 15 patients, with no change in 1. Lumbar Lordosis increased in 23 patients, with an average value of 2.3°. No patient exhibited progression in scoliosis and no lysis could be identified. There were three Grade I slips pre-op; none progressed.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 142 - 142
1 Apr 2012
Dhir J Carpenter C Pande R Pyrovolou N Ahuja S
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We do know that the use of stand-alone cage with no plate is prone to subsidence and segmental kyphosis. Cage and plate construct are prone to adjacent level ossification. Zero P (Synthes, UK) cage combines the functionality of spacer and anterior plate.

Radiological evaluation of subsidence of cervical spine after anterior cervical interbody fusion using Zero P cage system.

Method: Retrospective review of radiographic records of patients undergoing surgery between June 2008- Oct 2009. We evaluated lateral cervical standing radiographs before, after, 6 weeks, 3, 6 months of surgery. We measured subsidence (using Total Intervertebral Height (TIH). All measurements were done using Web 1000 (Impax Agfa). Two level was treated as single segment. Subsidence > 3mm was considered significant.

20 patients (11 male: 9 female) with median age of 51 yrs (40-65) underwent one (n=10) or two level (n= 10) cervical fusion. Immediately post-op there was increase in TIH in one and two level group by 1.74mm (1.61 and 4.25mm (1.48 respectively, which at 6 months reduced to 1.05mm (0.24 (p< 0.003) and 1.32mm (1.29 (p< 0.085) at 6 months respectively. Subsidence was seen in all cases and was rapid in first 3 months and then tailed off. It was significant (> 3mm) only in 2/20 (2%) patients at 6 months.

Early results indicate that spine alignment is maintained radiologically with no associated complications as screw loosening, cage extrusion etc.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 106 - 106
1 Apr 2012
Pande R Dhir J Pyrovolou N Ahuja S
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To evaluate Radiological changes in the lumbosacral spine after insertion of Wallis Ligament for Foraminal Stenosis.

Thirty two Levels in Twenty Six patients were followed up with standardised radiographs after insertion of Wallis Ligaments for Foraminal Stenosis. Wallis ligaments as a top-off or those with prolapsed discs were not included. The Radiological parameters compared were Anterior and Posterior Disc height, Foraminal height and width, The inter-vertebral angle (IVA), Lumbar lordosis and Scoliosis if any. The presence of slips and their progression post-op was noted, as was bony lysis if any.

There were ten males with thirteen levels and sixteen females with nineteen levels in the study. Eighteen levels (56.25%) were L4/L5, ten (31.25%) were L5/S1 and 4 (12.5%)were L3/L4. The average age in the series was 59.6 years (Range 37 – 89 yrs). Average follow up was 9.5 months (Range 2 to 36). The Average increase in Anterior disc height was 1.89 mm (+/−1.39), the posterior disc height increased by an average 1.09 mm (+/−1.14). Foraminal height increased by an average 3.85 mm (+/− 2.72), while foraminal width increased by 2.14 mm (+/− 1.38). The IVA increased in 16 and reduced in 15 patients, with no change in 1. Lumbar Lordosis increased in 23 patients, with an average value of 2.3°. No patient exhibited progression in scoliosis and no lysis could be identified. There were three Grade I slips pre-op; none progressed.

Foraminal dimensions and Disc height were consistently improved after Wallis insertion. Changes in IVA and Lumbar lordosis were however variable. A longer follow up is suggested to look for sustained improvement and the presence of lysis.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 324 - 324
1 May 2010
Mastrokalos D Koulalis D Zachos K Pyrovolou N Kontovazenitis P Lendi A Karaliotas G Sakellariou V Pandos P
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Purpose: The goal of this prospective study was to evaluate the results of arthroscopic meniscal repair with the FasT-Fix repair system.

Type of study: Prospective case series.

Methods: 83 meniscal repairs with the FasT-Fix meniscal repair system in 80 patients with a mean age of 29 years were performed between 2001 and 2004. Concurrent anterior cruciate ligament (ACL) reconstruction was performed in 70% of the cases. All tears were longitudinal and located in the red/red or red/white zone. Criteria for clinical success included absence of joint line tenderness, locking, swelling, and a negative McMurray test. Clinical evaluation included also the Lyscholm knee score, and KT-1000 arthrometry.

Results: The average follow-up was 38 months (range, 24–61 months). Six of 83 repaired menisci (7.23%) were considered failures according to our criteria. Therefore, the success rate was 92.77%. Time required for meniscal repair averaged 15 minutes. Postoperatively, the majority of the patients had no restrictions in sports activities. 92% had an excellent or good result according to the Lysholm knee score. Four patients had a restriction of knee joint motion postoperatively, and an arthroscopic arthrolysis was performed in one of them. Analysis showed that, age, length of tear, simultaneous ACL reconstruction, chronicity of injury, and location of tear did not affect the clinical outcome.

Conclusions: Our results, shows that arthroscopic meniscal repair with the FasT-Fix repair system provides a high rate of meniscus healing and offers reduction of both the risk of serious neurovascular complications and operative time.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 157 - 158
1 Mar 2009
Koulalis D Efstathopoulos N Papaparaskeva K Pyrovolou N Lenti A Konstantinou V Papachristou G
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Purpose of study: To investigate and compare the characteristics of the reconstructed articular surface microscopically and histologically after a time period of 6 weeks following the treatment of a focal defect of the right femoral head with subchondral drilling and autologous osteochondral transplantation in rabbits

Material and method: A 2,5 mm diameter and 3 mm depth iatrogenic osteochondral defect in the anterolateral weight bearing area of the right femoral head was created in 12 rabbits. In a group of 6 rabbits the lesion was treated with autologous osteochondral transplantation. The donor site for the transplant was the lateral condyle of the ipsilateral knee joint. The other group of 6 rabbits was treated with subchondral drilling. Both groups were sacrificed after a time period of 6 weeks and specimens were evaluated histologically under the classification system of the ICRS. For statistical analysis we used the Mann – Wittney test

Results: According to the ICRS score statistical significance was found for all variables between the 2 groups (subchondral drilling 6 weeks vs autologous osteochondral transplantation 6 weeks).: articular surface (p=0,049), matrix (p=0,003), cell distribution (p< 0,0005), subchondral bone (p=0,010), cartilage mineralization (p=0,0) except cell population viability.

Discussion: In comparison to subchondral drilling, autologous osteochondral transplantation provided better results concerning the smoothness and continuity of the articular surface, the consistency of the matrix with dominance of the hyaline and mixed hyaline – fibrocartilage type of tissue, the normality of subchondral bone and the columna r distribution of cells. The viability of the cell populations was the same for both methods. The incorporation of the osseous part of the graft was successful in all cases and the surgical procedure did not produce any necrosis of the femoral head.

Conclusion: In cases of focal osteochondral defect of the femoral head in rabbits, reconstruction of the articular surface through autologous osteochondral graft transplantation gives superior macroscopical and histological results in comparison to subchondral drilling