Incorrect registration during computer assisted total knee arthroplasty (CA-TKA) leads to malposition of implants. Our aim was to evaluate the tolerable error in anatomic landmark registration. We incorrectly registered the femoral epicondyles, femoral and tibial centers, as well as the malleoli and documented the change in angulation or rotation. We found that the distal femoral epicondyles were the most difficult anatomic landmarks to register. The other bony landmarks were more forgiving. Identification of the distal femoral epicondyles has a high inter- and intra-observer variability. Our observation that there is less than 2 mm of safe zone in the anterior or posterior direction during registration of the medial and lateral epicondyles may explain the inability of CA-TKA to improve upon the outcomes of conventional TKA.

Restoration of the joint line of the knee during primary and revision total knee arthroplasty is one of many critical steps that directly influence patient outcomes. Fifty MRI scans of normal atraumatic knees were analyzed to determine a quantitative relationship between the joint line of the knee and the bony landmarks of the knee joint: femoral epicondyles, metaphyseal flare of the femur, tibial tubercle, and proximal tibio-femoral joint. We describe the relationship of these six anatomic landmarks about the knee in a gender and size independent manner. This description supports a simple three-step algorithm allowing orthopaedic surgeons to calculate, instead of estimate, the location of the joint line of the knee.