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The Bone & Joint Journal
Vol. 103-B, Issue 8 | Pages 1400 - 1404
1 Aug 2021
Sim FCJ Birley E Khan AL Loughenbury PR Millner P

Aims

The aim of this study was to determine whether there is an increased prevalence of scoliosis in patients who have suffered from a haematopoietic malignancy in childhood.

Methods

Patients with a history of lymphoma or leukaemia with a current age between 12 and 25 years were identified from the regional paediatric oncology database. The medical records and radiological findings were reviewed, and any spinal deformity identified. The treatment of the malignancy and the spinal deformity, if any, was noted.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVI | Pages 69 - 69
1 Jun 2012
Graham SM Fishlock A Millner P Sandoe J
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Purpose of study

The aim of this study was to identify the incidence of Gram negative bacterial vertebral osteomyelitis (VO) within our unit during a 3-year study period and evaluate if this corresponds to published evidence that the occurrence is increasing.

Methods

Between May 2007 and May 2010, all patients, over the age of 18 years, suffering from Gram-negative VO were identified and their microbiological diagnoses were evaluated. All patients were treated within a large tertiary spinal surgery unit in Leeds.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 119 - 119
1 Apr 2012
Borse VH Millner P Hall R Kupur N
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To investigate and compare the biomechanical characteristics of Bipedicular versus Unipedicular Vertebroplasty in cadaveric vertebra

Cadaveric single level vertebra were used to evaluate Bipedicular versus Unipedicular Vertebroplasty as an intervention for vertebral compression fractures

Cadaveric vertebra were assigned to two arms: Arm A simulated a wedge fracture followed by bipedicular cement augmentation; Arm B simulated a wedge fracture followed by unipedicular cement augmentation. Micro-CT imaging was performed to assess vertebral dimension, cement fill volumes and bone mineral density. All augmented specimens were then compressed under a static eccentric flexion load to failure.

Pre and post augmentation failure load and stiffness were used to compare the two groups.

Results suggest, when compared with actual failure strength, that the product of bone mineral density and endplate surface area gave a good prediction of failure strength for specimens in both arms. The mean cement volume fill of augmented vertebral bodies was 22.8% ± 7.21%. The bipedicular group showed a reduction in stiffness but an increase in post augmentation failure load of 1.09. The unipedicular group also showed a reduction in stiffness but showed a much greater increase in post augmentation failure load of 1.68.

Preliminary data from this study suggests there is a significant reduction in stiffness following both bipedicular and unipedicular vertebroplasty. There is a significant increase in failure load post augmentation in the unipedicular group.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 91 - 91
1 Apr 2012
Pai S Michael R Rao A Dunsmuir R Millner P
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To evaluate the efficacy of Vacuum Assisted Closure (VAC) in the management of post surgical spinal sepsis.

A retrospective analysis was performed of patients with severe post operative spinal wound infections treated using a combination surgical debridement, antibiotics and VAC therapy.

Full records were available for a total of twenty adult all of whom had had prior thoracic or lumbar instrumentation. Comorbidities included disseminated carcinomatosis (25 % of patients), Ankylosing spondylitis (5 %), rheumatoid arthritis (5%) and Polio (5%). In one patient there had been a prior history of irradiation of the surgical field. Most infections treated by this regime were identified within two weeks following surgery. At surgery infection deep to the dorso-lumbar fascia was found in 87 % of cases. It was possible to retain instrumentation in 60 % of cases. An average of three trips to theatre were required prior to wound closure, which was possible in 95 % of cases. The VAC device was left in situ for an average of 11 days. Complications included recurrence of infection necessitating further treatment in 20 % of cases, wound dehiscence necessitating healing by secondary intention in 5%, the need for free flap wound cover in 5 % and death from unrelated causes in 5%.

VAC therapy may facilitate the management of wound sepsis following spinal surgery in susceptible patients allowing the maintenance of instrumentation and surgical correction.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 64 - 64
1 Apr 2012
Michael A Loughenbury P Dunsmuir R Rao A Millner P
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To determine the current practice of scoliosis surgery in the UK.

A 10 point questionnaire was constructed to identify the philosophy of surgeons on various aspects of scoliosis surgery such as choice of implant, bone graft, autologous blood transfusion (ABT), cord monitoring and computer assisted surgery. Results are compared with the current best evidence.

Consultants and Fellows attending the 2009 British Scoliosis Society meeting. 50 questionnaires were completed: 45 Consultants and 5 Fellows.

All pedicle screw construct favored by 25/50, hybrid 24/50 (one undecided). Posterior construct of less than 10 levels, 20/50 would not cross-link, 11/50 used one and 19/20 used two or more. More than ten levels 17/50 considered cross-links unnecessary, 4/50 used one and 29/50 used two or more. 88% preferred titanium alloy implants, while a mixture of stainless steel and cobalt chrome was used by others. For bone graft, substitutes (24), iliac crest (14), allograft (12) and demineralised bone matrix (9) in addition to local bone. 10/50 would use recombinant bone morphogenetic protein (3 for revision cases only). 39/50 routinely used intra-operative cell salvage or ABT drains and 4/50 never used autologous blood. All used cord monitoring, Sensory (19/50), Motor (2/50) and combined (29/50). None used computer-aided surgery. 26 operated alone 12 operated in pairs and 12 varied depending on type of case.

This survey has brought to light interesting variations in scoliosis surgery in UK. It may reflect the conflicting evidence in the literature.