Between July 2000 and December 2002, 263 consecutive patients across 5 surgical centers underwent to a revision surgery of a failed acetabular component in which TM acetabular components were used.

There were 150 women and 113 men with a mean age of 69.5 years.

The indication for acetabular revision was aseptic loosening in 186 cases (70.7%)

Clinical evaluations were performed using the Harris hip score, the WOMAC and UCLA activity scale.

Implant and screw position, polyethylene wear, radiolucent lines, gaps, and osteolysis were assessed. Preoperatively, acetabular bone deficiency was categorized using the classification of Paprosky et al.

Statistical analysis was performed using nonparametric correlations. Standard life table was constructed, and the survival rate was calculated by means of Kaplan-Meier method.

The overall mean follow-up was 73.6 months (range, 60–84 months), and no patient was lost to follow-up.

The preoperative HHS rating improved from a mean of 43.6 ± 11.4 before revision, to a mean of 82.1 ± 10.7.

None of the patients was re-revised for loosening. The cumulative prosthesis survival was 99.2% at 5 years.

There was no correlation found between the various degrees of acetabular bony defect and the magnitude of clinical results (independent of pre-revision Paprosky grade). The use of component augments allowed us to minimize the volume of morsellized allograft used for defect repair.

TM acetabular component demonstrates promising midterm results similar to those reported by other authors.

INTRODUCTION: In guided tissue regeneration a membrane is used for defect isolation to protect it against invasion from surrounding tissues and to keep intrinsic healing factors ‘in situ’. This technique has been successfully used in maxillo-facial surgery, but short experience has been reported in long-bone defects, with synthetic membranes and with variable results. In the other hand, calcification and ossification inside the arterial wall have been described.

OBJECTIVE: The aim of the study was to evaluate the use of cryopreserved aorta allografts as membranes for guided tissue regeneration in comparison with expanded poly-tetra-fluoro-ethylene (e-PTFE) synthetic membranes.

MATERIAL & METHODS: Prospective, randomized, blinded study in 15 New-Zeland rabbits. 10 mm mid-diaphyseal defects were created in both radii: 10 defects were covered with a cryopreserved aortic allograft as a tube, 10 with an e-PTFE membrane and 10, with no barrier membrane, served as controls. Animals sacrifice at 6–12–24–30 months. Studies: X-rays, CT, MR, morpho-densitometric analysis, electronic and optical microscopy. Immuno-cytochemistry on tissues and arterial wall cells cultured.

RESULTS: None of the control defects healed. Nine defects covered with an artery completely reconstituted, but only six of those covered with e-PTFE, with a nearly normal cortical-medullar pattern and with progressive increasing in density and thickness of medullar and cortical to values similar to those of the normal bone. Histological studies showed no inflammatory response to the arterial graft, direct union between the artery and the regenerated bone and even mature bone between the elastic laminae of the arterial wall, suggesting superior biocompatibility properties. Immuno-cytochemistry and ultrastructural studies suggest that arterial allografts could act not only as membrane barriers, with additional osteoinductive properties due to trans-differentiation of viable arterial wall cells (endothelial, smooth muscle and/or tissue specific stem cells) towards osteoblastic cells, and also due to ossification secondary to changes in proteins of the arterial extracellular matrix. This could be the application of the process of arterial wall calcification and ossification (usually seen in arteriosclerosis, gender, diabetes or kidney failure) for regeneration of long-bone defects.

CONCLUSION: Cryopreserved aortic allografts can be used as membrane barriers for guided bone regeneration, with superior results to e-PTFE membranes.

Introduction. Alternative bearing surfaces to polyethylene have been introduced to avoid the appearance of osteolysis in THR. The aim of this study has been to perform prospective analysis of the data from a multi-center clinical trial for assessing the incidence of early alumina-specific-complications.

Material and Methods. We analysed 310 Cerafit cups associated with a Multicone-HA stem using alumina-on-alumina bearings implanted in four institutions from 1999 to 2003, with a mean follow-up of 4.7 years. Patients’ mean age was 52.8+13.4 years. Linear femoral head penetration was analysed using a software package.

Results. There were 4 revisions: 2 revisions due to dislocations resulting poor surgical technique (1 cup and 1 stem) and 2 revisions after a trauma (1cup and 1 stem). There was 1 alumina liner fracture 36 months after implant in a hip with a horizontal acetabular angle (35°) and a thin alumina liner (size 50/32). The other cases showed good clinical and radiographic results at the end of follow-up. The radiographic difference between the femoral head and cup centres at 6 weeks postsurgery was 2.48+0.60 mm, without changes in the course of the follow-up. The mean linear femoral head penetration was unreliable (0.00186+0.0032 mm/year) because it was below the mean error for the measurement system.

Conclusions. These data demonstrate that Cerafit Alumina-on-Alumina prostheses show excellent results after 5 years. Liner fractures are uncommon. Despite the blurred alumina images, the digitized method, although not totally accurate and used only for a general estimate, allows us to measure the approximate distance between the centre of the cup and the centre of the femoral head. Changes in linear femoral head penetration were not seen in any hip. Continued follow-up should determine if reduction in wear among the alumina-on alumina bearings results in less osteolysis.

Background and objective: In guided tissue regeneration a membrane is used for defect isolation to protect it against invasion from surrounding tissues and to keep intrinsic healing factors ‘in situ’. This technique has been successfully used in maxillo-facial surgery, but short experience has been reported in long-bone defects, with synthetic membranes and with variable results. In the other hand, calcification and ossification inside the arterial wall have been described. The aim of the study was to evaluate the use of cryopreserved aorta allografts as membranes for guided tissue regeneration in comparison with expanded poly-tetra-fluoro-ethylene (e-PTFE) synthetic membranes.

Methods: Prospective, randomized, blinded study in 15 New-Zeland rabbits. 10 mm mid-diaphyseal defects were created in both radii: 10 defects were covered with a cryopreserved aortic allograft as a tube, 10 with an e-PTFE membrane and 10, with no barrier membrane, served as controls. Animals sacrifice at 6-12-24-30 months. Studies: X-rays, CT, MR, morpho-densitometric analysis, electronic and optical microscopy. Immuno-cytochemistry on tissues and arterial wall cells cultured.

Results: None of the control defects healed. Nine defects covered with an artery completely reconstituted, but only six of those covered with e-PTFE, with a nearly normal cortical-medullar pattern and with progressive increasing in density and thickness of medullar and cortical to values similar to those of the normal bone. Histological studies showed no inflammatory response to the arterial graft, direct union between the artery and the regenerated bone and even mature bone between the elastic laminae of the arterial wall, suggesting superior biocompatibility properties. Immuno-cytochemistry and ultrastructural studies suggest that arterial allografts could act not only as membrane barriers, with additional osteoinductive properties due to trans-differentiation of viable arterial wall cells (endothelial, smooth muscle and/or tissue specific stem cells) towards osteoblastic cells, and also due to ossification secondary to changes in proteins of the arterial extracellular matrix. This could be the application of the process of arterial wall calcification and ossification (usually seen in arteriosclerosis, gender, diabetes or kidney failure) for regeneration of long-bone defects.

Conclusion: Cryopreserved aortic allografts can be used as membrane barriers for guided bone regeneration, with superior results to e-PTFE membranes.

Introduction.- Some of the recommended alternatives to increase the cementless acetabular cups stability are the plasma sprayed porous coated and HA and the press-fit impaction. The incorporation of three peripheral fins improves final fixation avoiding micromotion at the immediate post operative period. From 1992 we have implanted 4068 cups, the majority of them in primary cases (78%). The rest 22% in revision cases.

Cup characteristics: hemispheric with fins to improve prumary fixation and HA coating; ring-long ystem in common with other Biomet models, reason why liner are interchangeables.

Material and methods.- 4.068 Bihapro cups (Biomet-Merck) were implanted at a multicenter study in three Hospitals, adjoined to the University, between 1992 and 2003. This is a press-fit model with a porous surface coated with HA and three peripheral fins to improve primary fixation and also dome holes to allow the use ob bone screws.

Prymary indication: osteoarthritis (76%), AVN (7%), fractures (8%), dysplasias (3%), rheumatoid arthritis (6%). Surgical approach: lateral (49%), posterolateral (34,2%), anterior (16,8%). Prophylaxis: antitrombotic (LMWH), antibiotic (1st generation cephalosporins), heterotopic ossification (indomethacin).

Results.- Results. 24 patients showed dislocation and 47 % had some degree of periarticular ossification one year alter surgery; the approach used did not show significative differences. The survival study was done using Kaplan-Meier’s curve. The end-point for failure in this study was the need to perform aesptic revision surgery; being the survival at 9 years of 99.49 % (CI 95 % 99.08 – 99.90). Seven cases needed revision surgery (0.3 %); two cases for migration of the cup and five cases for iterative dislocations.

Conclusions.- Acetabular cups with Plasma Spray Porous Coating in combination with HA, results stable at mid term. The supplementary fixation of the three peripheral fins avoids micromotion optimizing long-term fixation.