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Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 12 - 12
1 Jan 2016
Al-Khateeb H Mahmud T Naudie D McCalden RW
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INTRODUCTION

The development of new bearing surfaces for total joint replacement is constantly evolving. Oxidized zirconium (Oxinium) has been introduced for use in both total hip arthroplasty (THA) and total knee arthroplasty (TKA). The aetiology of wear is multifactorial and includes adhesive, abrasive, third-body and fatigue wear mechanisms. Oxinium femoral components have demonstrated clear improvements in wear characteristics in-vitro. The purpose of this prospective study was to evaluate the mid-term (minimum 5 year) clinical and radiographic results and survivorship of the Genesis II™ knee implant system using an Oxinium femoral component.

METHODS

Between January 2001 and December 2008, 382 Genesis II Oxinium (Smith & Nephew) primary total knee arthroplasties (TKA) (313 patients) were implanted at our institution. A comparison with a cohort of 317 patients (382 knees) who received a Genesis II knee implant using a ‘conventional’ cobalt-chrome (Co-Cr) femoral component was performed during the same time period. Prospective data was collected on all patients including demographics (age, BMI, diagnosis) as well as pre and postoperative clinical outcome scores (SF-12, WOMAC, and knee society clinical rating scores (KSCRS). Radiological analysis for evidence of osteolysis and loosening was performed in all patients. Comparisons were performed to determine differences between the Oxinium and Cobalt Chrome cohorts. Kaplan-Meier survival analysis was performed to show cumulative survival over time. Failure was defined as femoral component revision due to any cause.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 11 - 11
1 Jan 2016
Al-Khateeb H Mahmud T MacDonald S McAuley JP
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Objectives

Porous metal surfaces have been a popular option for acetabular component fixation in total hip arthroplasty (THA). New THA component designs are introduced periodically with the expectation of better wear properties and survivorship. Since its approval for use in 2002 there have been few clinical outcome studies published on the Pinnacle acetabular cup system. We hypothesised that the hemispherical porous coated Pinnacle acetabular cup system with a range of cup options and bearing surfaces would give us predictably good fixation and survivorship at five years post implantation.

Materials and Methods

A total of 1391 Pinnacle acetabular cups (De Puy, a Johnson & Johnson company, Warsaw IN) were implanted between the period March 2003 to August 2011 by four senior surgeons. There were a total of 29 patients requiring revision surgery. Of these revisions, 23 were excluded from the final analysis. Sixteen were for early infection requiring debridement of the hip joint and exchange of the modular liner and femoral head. Five patients sustained femoral peri-prosthetic fractures requiring further surgery with retention of the acetabular component in all cases. Of the remaining 8 revision cases, only 6 had more than two years follow-up. All patients had pre and post-operative Harris hip scores, WOMAC and SF-12 scores. All patients were assessed with serial radiographs immediately post-operatively, 3 months, 1 year, 2 years, every 2 years thereafter. Component migration and revisions (excluding infection and peri-prosthetic fractures) are reported as failures. Post-operative radiographs were evaluated for component migration. Kaplan-Meier survivorship curves were drawn to show survivorship for cup type and bearing type.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 88 - 88
1 Sep 2012
Mahmud T Somerville L Bourne RB
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Purpose

The most common procedure for advanced osteoarthritis of the knee is a total knee arthroplasty (TKA). Unicompartmental knee arthroplasty (UKA) has become a popular treatment for isolated medial compartment osteoarthritis. The purpose of this study was to look at the functional outcomes following these two procedures.

Method

Prior to January 1995, 87 Miller-Galante UKAs (MG UKA) were performed in 68 patients. These were compared to a gender, age, BMI matched Anatomic Modular Knee (AMK) cohort of equal size performed during the same time period. Patients were evaluated using a validated clinical outcome score (Knee Society score) and radiographs. Kaplan-Meier survival analysis was performed.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 244 - 244
1 Sep 2012
Jones M Mahmud T Narvani A Hamid I Lewis J Williams A
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Data was collected on 139 eligible patients a minimum of 18 months post surgery who had had 2 or more ligaments reconstructed. 63 patients were available for clinical follow up. It is the largest single surgeon series studied.

27% of injuries were high energy traffic accidents. 73% were low energy, mainly sports related. 63% of patients were delayed referrals to our unit. Of these nearly 48% had already undergone knee surgery, often more than 6 months post injury. 17% of all cases presented with failed ligament reconstructions. Of those patients followed up 19% were operated upon within 3 weeks of injury, 56% were delayed reconstructions with a mean time to surgery of 21 months and 25% were revision reconstructions. Time to follow up ranged from 18 months to 10 years.

The median KOS ADL, KOS Sports Activity and Lysholm scores for uni-cruciate surgery were all better than those for bi-cruciate surgery. All results were better for acute rather than chronic cases, which in turn were better than those for revision cases. The Tegner score showed that only acute uni-cruciate reconstructions returned to their pre-injury level.

TELOS stress radiographs demonstrated a mean post drawer of 5.9 mm side-to-side difference after reconstructions involving the PCL. IKDC grades showed 6% of knees were normal and 57% were nearly normal.

37% required further surgery, mainly to increase movement or for hardware removal. There was 1 deep infection and 2 cases of thrombosis. There were no vascular complications but 2 had transient nerve injuries.

Multi-ligament surgery can produce good functional outcomes but the knee is never normal. There is an increased risk of PCL laxity post op. Early referral to a specialist unit is suggested as delayed referral to a specialist unit potentially subjects the patient to unnecessary surgery and may affect outcome.