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Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_16 | Pages 36 - 36
1 Dec 2015
Lepetsos P Stylianakis A Leonidou A Argyris D Anastasopoulos P Lelekis M Tsiridis E Macheras G
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In spite of its incidence decreasing to 1% nowadays, prosthesis-related infections remain a research, diagnostic, therapeutic and cost-related problem. Early diagnosis, selection of an appropriate surgical strategy, accurate identification of the responsible microorganisms and construction of an appropriate antibiotic regimen are essential elements of any management strategy. Our study aim was firstly to compare the diagnostic accuracy of conventional periprosthetic tissue culture and culture of fluid derived from vortexing and bath sonication of the explanted hardware and secondly to investigate the role of possible metabolic factors affecting the sensitivity of the sonication method.

We investigated 70 patients undergoing revision hip or knee arthroplasty because of loosening of the prostheses, at our institution, between October 2011 and November 2013. Patients’ medical history and demographic characteristics were recorded. We compared the culture of samples obtained by sonication of explanted hip and knee prostheses with conventional culture of periprosthetic tissue for the microbiological diagnosis of prosthetic-joint infection.

Infectious Diseases Society of America (IDSA) Guidelines were used for the definition of prosthetic-joint infection. Thirty-two patients had septic loosening and 38 aseptic loosening (48 hip prostheses and 22 knee prostheses). The sensitivity of sonication fluid culture was 81.25% and the sensitivity of conventional tissue cultures was 56.25% (p-value = 0.043). The sensitivity of the sonication method was statistically higher in obese, diabetic patients, with age above 60, in uncemented arthroplasties and in arthroplasties because of primary osteoarthritis (p-values < 0.05).

The sonication method represents a reliable test for the diagnosis of prosthetic – joint infections with a greater sensitivity than the conventional periprosthetic tissue cultures, especially in obese, diabetic patients, with age above 60, in uncemented arthroplasties and in arthroplasties because of primary osteoarthritis.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_18 | Pages 6 - 6
1 Apr 2013
Leonidou A Kiraly Z Gality H Apperley S Vanstone S Woods D
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In treating open long bone fractures our current policy includes early administration of intravenous antibiotics and surgery on a scheduled trauma list. We have reviewed our infection rates 6 years following the initiation of this policy. 220 fractures were studied. Our records included time of administration of antibiotics, time to theatre and seniority of surgeon. We identified cases of superficial or deep infection. Surgical debridement occurred within 6 hours of injury in 45% of cases and after 6 hours in 55%. Overall infection rates were 11% and 15.7% respectively. Intravenous antibiotics were administered within 3 hours of injury in 80% of cases and after 3 hours in 20% of cases. Overall infection rates were 14% and 12.5% respectively. Infection rates where the most senior surgeon present was a consultant were 9.5% compared to 16% with the consultant absent. Our results suggest that the change in policy may have contributed to an improvement of the deep infection rate to 4.3% from the previous figure of 8.5%, although this decrease was not statistically significant. Time to theatre has not adversely affected the infection rate, and presence of a senior surgeon may have improved infection rates, although both trends were not statistically significant.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 99 - 99
1 Jan 2013
Leonidou A Pagkalos J Lepetsos P Antonis K Flieger I Tsiridis E Leonidou O
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Introduction

Early identification and conservative management of paediatric Monteggia fractures has been shown to correlate with good results. Nevertheless, several authors advocate more aggressive management with open reduction and internal fixation (ORIF) for unstable fractures. We herein present the experience of a tertiary paediatric hospital in the management of Monteggia fractures.

Methods

41 patients with Monteggia fractures (26 male and 15 female) were admitted and treated over a period of 20 years (1989 to 2009). The age of the patients ranged between 3 and 14 years (mean 7.5 years). Based on the Bado Classification, 29 fractures were type I, 3 were type II, 8 type III and 1 fracture was classified as type IV. Out of the 41 patients, 32 were managed with manipulation under anaesthesia (MUA) and above elbow plaster, whereas 9 underwent open reduction and internal fixation (ORIF) of the ulna.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 109 - 109
1 Jan 2013
Pagkalos J Leonidou A Lepetsos P Antonis K Flieger I Tsiridis E Leonidou O
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Introduction

Lateral humeral condyle fractures account for 17% of the distal humeral condyle fractures. They affect children between 5 and 10 years of age. Recent reports advocate closed reduction and internal fixation for the less displaced fractures.

Methods

We retrospectively reviewed children treated with open reduction internal fixation of these fractures at a single institution over a period of 13 years. All cases of lateral humeral condyle fractures treated with ORIF were identified through the trauma register. Case notes and radiographs were retrieved. Fracture classification, mode of fixation, time to union, and clinical examination at latest follow up were reviewed.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 155 - 155
1 Sep 2012
Leonidou A Lepetsos P Flieger I Pettas N Antonis K Leonidou O
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Introduction

The incidence of spondylolysis is estimated about 5–6% in the general population and accounts for one of the most frequent cause of backpain in the adolescent. The purpose of this study is to present our results from the management of these patients.

Patients and Methods

During the period 1993–2003, 25 children with spondylolysis and spondylolisthesis were managed in our department. Apart from radiographic studies, in cases with a history of acute trauma, a bone scan as well as a CT or MRI scan were performed. There were 13 male and 12 female patients with a mean age of 10.5 years (5–14 years). There were 15 cases of spondylolysis, one at L3 level, 3 at L4 and 11 at L5. 10 patients had spondylolisthesis, 8 of the isthmic type and 2 of the dysplastic type. THe mean follow up of the patients was 6.5 years.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 156 - 156
1 Sep 2012
Leonidou A Boyce Cam N Chambers I
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Introduction

Femoral neck fractures are an increasingly common injury in the elderly. Frequently these patients present taking Clopidogrel, an irreversible inhibitor of platelet aggregation. Although this is associated with an increased risk of intra-operative bleeding and also an increased risk of spinal haematoma where regional anaesthesia is employed, the recent SIGN (Scottish Intercollegiate Guidance Network) guidelines recommend that surgery should not be delayed.

Methods

We conducted a retrospective review of consecutive patients admitted with femoral neck fractures between April 2008 and October 2009. Patients on Clopidogrel were identified and data including ASA grade, time to operation, medical co-morbidities, and post-admission complications were recorded. Comparative information from the National Hip Fracture Database was used.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 360 - 360
1 Jul 2011
Flieger I Pettas N Leonidou A Liarakos N Platanitis I Leonidou O
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The cause of Legg-Calve Perthes disease, 97 years after its original description remains undefined. In the present study we examined factors, which were correlated with a favourable or negative impact on the outcome of surgical treatment.

From a total of 98 children, treated during the period 1994–2006, we studied 20 cases (classified as Catterall III and IV), treated surgically. The average age was 7.4 years (4–13 years). We studied in comparison the most common procedures performed: these were the varus femoral osteotomy (12) and the lateral shelf acetabuloplasty (7). The subtrochanteric osteotomy yielded superior radiological results Stuhlberg I–II (I:6, II:6), than the lateral shelf procedure Stuhlberg II–IV (II:3, III:3, IV:1). The clinical results were similar between the two groups according to the Barrett scale, excellent or good.

Regarding the subtrochanteric osteotomy the most important factor was the precise varisation of the femoral neck and secondly the timing of surgical treatment early during the fragmentation stage of the disease, before the femoral head is significantly distorted. The most important positive factor regarding the lateral shelf procedure appears to be the accuracy of the surgical technique, in order that the graft coverage of the femoral head is accurately placed on the hip capsule. Negative factor for the lateral shelf procedure in one case was early weightbearing, which resulted in collapsing of the femoral head. It appears that with extensive necrosis (Caterall IV) the femoral head isn’t biomechanically enough resistant with this procedure to resist loads that result from early ambulation.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 162 - 162
1 Feb 2004
Leonidou O Flieger I Pettas N Papadakis P Pertsemlides D Leonidou A
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Fracture separation of the distal epiphysis of the tibia constitutes 10% of all epiphyseal fractures occurring in children. We studied 120 cases, which were treated stationary at our Department over the 10 year period between 1990 – 2000. The ratio between boys and girls was 2:1. The average age was 12,5 years (8–15 years). In 96 cases (80%) the injury occurred after a fall on the playground, in 12 cases (10%) after a roadtraffic accident and in 12 cases (10%) after a fall from a height. The average follow up is 7,2 years (2–12 years). According to the Salter-Harris classification 6 cases (5%) were Salter I, 90 cases (80%) were Salter II, 9 cases (9%) were Salter III and 6 cases (5%) were Salter IV. In all cases a closed reduction under general anaesthesia was attempted. If the reduction was succesful a whole leg plaster was applied. If the reduction was unstable a transcutaneous stabilisation or open reduction and internal fixation was performed. If a reduction could not be acchieved open reduction and internal fixation (ORIF) was performed using Kirschner wires or screws. Closed reduction was performed in 94 cases (78,34%), transcutaneous osteosynthesis in 2 cases (1,66%) and ORIF in 24 cases (20%).

We conclude that sports and for instance football is the main cause, where this injury occurs. The treatment is mainly conservative and complications are rare, when anatomical reduction is acchieved. The most common complication is angulation resulting from the injury at the epiphyseal plate, for instance varus angulation, which occurs from supination injuries mainly of Salter-Harris type III and IV.