Infection remains a serious complication of total hip replacement (THR). Management options have been developed to improve clearance of infection while maintaining joint function during treatment and improve outcome at reimplantation. The gold standard in management is generally considered to be implant removal and thorough debridement with antibiotic therapy delivered systemically and locally with impregnated spacers. However, some surgeons still prefer to use Girdlestone resection arthroplasty, thus not leaving any foreign body The aim of this study was to compare infection clearance rates, radiographic and functional outcomes after two-stage revision of total hip arthroplasty with (1) gentamicin-loaded bone cement spacer or (2) Girdlestone resection arthroplasty as the first stage of treatment. We retrospectively reviewed data of 48 patients (20 females, 28 males) with implanted spacers and 53 patients (21 females, 32 males) treated with resection arthroplasty at tertiary care university hospital in the years 2008–2012. Minimum follow-up was three years (range, 3–7 years). Treatment choice was at the operating surgeons's discretion. In the spacer group, mean age at the time of first stage was 62 years (range 24–79 years), time from primary replacement 14 months, and the time from the first to the second stage of the revision 7 months. At latest, minimum 3-year follow-up, two were still ambulating with a spacer in situ, and five were re-revised with another spacer before the reimplantation of the THR. In the resection arthroplasty group, mean age at the time of first stage was 64 years (range, 37–87 years), time from primary replacement 13 months, and the time from the first to the second stage of revision − 10 months. At the latest follow-up, four patients were ambulating with resection arthroplasty, one did not clear his infection and one died of unrelated causes. The cure ratio appeared to be the same within both groups (Fisher exact test, p=0.08). Patients with spacers achieved better functional results, used less supports for ambulation and had less leg length discrepancy after the second stage of revision. In the light of those results, we cannot recommend for the use of resection arthroplasty in the treatment of the infected THR.
The aim of the study was to analyze effectiveness and safety of packing the medullary canal of the tibia and femur with Herafill (Heraeus Medical GmbH, Wehrheim, Germany), a void filler and antibiotic carrier, during second stage revision total knee arthroplasty(TKA) for periprosthetic joint infection (PJI). We used hybrid cementation technique for the fixation of TKA components with antibiotic-loaded bone cement for femoral and tibial component and cementless stem extensions. Two groups of 27 consecutive patients each were matched for gender and age. The study group received Herafill, while the control group did not. Otherwise, the treatment protocol remained the same for both groups. The average follow-up was 48 months (minimum of 34 months).Background
Methods
The aim of the study was to assess the results of treating knee osteoarthrosis with total knee arthroplasty (TKA) after previous tibia and/or femur fractures resulting in axial limb deformities. Thirty-six knees (34 patients) were operated on. At the most recent follow-up, 4.8 years after surgery, all but one patient demonstrated an improvement in both clinical and functional KSS. This male patient required revision after 2 years due to tibial component aseptic loosening. Improved range of motion was generally noted, especially extension, however, two patients with both tibia and femur fractures had worse results. TKA is an effective method of treatment for patients with arthrosis after a previous femur or tibia fractures. When deformity is severe semi-constrained or constrained, implants with extensions may be necessary.
Optimal knee joint function obviously requires a delicate balance between the osseous anatomy and the surrounding soft tissues, which is distorted in the case of joint line elevation (JLE). Although several studies have found no correlation between JLE and outcome, others have linked JLE to inferior results. The purpose of this in vitro investigation was to evaluate the effect of JLE on tibiofemoral kinematics and collateral ligament strains. Six cadaver knees were equipped with reflective markers on femur and tibia and CT scans were made. A total knee arthroplasty (TKA) was performed preserving the native joint level. The knees were then tested in passive flexion-extension and squatting in a knee kinematics simulator while marker positions were recorded with an optical system. During squatting quadriceps forces were measured as well as tibio-femoral contact pressures. Finally, a revision TKA was performed with JLE by 4 mm. The femoral component was downsized and a thicker insert was used. The knees were again tested as before. Based on the bony landmarks identified in the CT scans and the measured trajectories of the markers, relative tibiofemoral kinematics could be calculated as well as distance changes between insertions of the collateral ligaments. Statistical tests were carried out to detect significant differences in kinematic patterns, ligaments elongation, tibiofemoral contact pressures and quadriceps forces between the primary TKA and after JLE.Introduction
Materials and Methods
