The purpose of this study was to propose a new classification based on the structural, anatomical and biomechanical properties of the odontoid process, to evaluate the outcome and to suggest the adequate treatment in relation to the specific fracture type. The files of 97 patients with odontoid process fractures admitted to our institution were reviewed. The external and internal anatomy of the axis has been studied. The fractures were classified according to the proposed new classification. The method was tested for reliability and validity. Mean follow-up was 14 years. Intraobserver and interobserver agreement was excellent with intraclass correlation coefficients at levels of 0.98 and 0.85 respectively. Four types of odontoid process fractures are distinguished; type A fractures are avulsion fractures involving the tip of the odontoid; type B fractures are fractures of the neck between the lower edge of the transverse ligament and the line connecting the medial corners of the upper articular facets of the axis; type C fractures involve the area between the previously mentioned line and the base of the odontoid process (type C1) or extend to the body of the axis (type C2); type D fractures are complex fractures involving more than one level of the odontoid process. Classification of odontoid process fractures has to be reconsidered as novel imaging technology has shown new patterns of fractures. Computed tomography scan with image reconstruction is mandatory. The analysis of the imaging data in the present study justifies the new classification.