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Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_16 | Pages 80 - 80
1 Apr 2013
Dogaki Y Lee S Niikura T Koga T Okumachi E Waki T Kakutani K Nishida K Kurosaka M
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Introduction

iPSCs represent a promising cell source for bone regeneration. To generate osteoprogenitor cells, most protocols use the generation of embryoid bodies (EBs). However, these protocols give rise to heterogeneous population of different cell lineage.

Hypothesis

We hypothesized that a direct plating method without EB formation step could be an efficient protocol for generating a homogeneous population of osteoprogenitor cells from iPSCs.