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Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_23 | Pages 26 - 26
1 Dec 2016
RISK REDUCTION ON PJI WITH S. AUREUS ERADICATION THERAPY IN THA
Thomas A Koenraadt K Joosten P van Geenen R Bolder S
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Aim

Prosthetic joint infection (PJI) is a major complication in THA. Nasal carriage with S. Aureus is a well-defined risk factor for infection in hospitalized patients. Risk for infection is reduced up to 50% by eradication therapy. Since PJI rates are very low and only 25% of the population are carriers, significant differences are hard to show and reports on PJI have been inconclusive. We analysed the effect of S. Aureus eradication therapy in THA.

Methods

From 2011, patients receiving THA are screened for S. Aureus carriage and carriers are treated. This group was retrospectively compared with a historical THA group in which no screening and eradication therapy was done. We assumed similar carrier rates in both groups and calculated the risk reduction of eradication therapy for PJI in comparison to the historical carriers without treatment. Fisher's Exact test was used to compare outcome.