The incidence of hip fractures is rising worldwide. Hip fracture patients with a cardiac murmur have an echocardiogram pre-operatively in our unit. We assessed the impact of obtaining a pre-operative echocardiogram on treatment of such patients, using National Confidential Enquiry into Patient Outcome and death (NCEPOD) report 2001 as gold standard. We undertook a retrospective audit of hip fracture patients (N=349) between 01/06/08 and 01/06/09. 29 patients had pre-operative echocardiogram (echo group). A computer generated randomised sample of 40 patients was generated from N, ‘non-echo’ group. Data was obtained from medical records and the Hospital Information Support System. The groups were compared using Student's t test. Age and gender distribution were similar in both groups. 29 patients had pre-operative echo. The indication for requesting an echocardiogram pre-operatively was an acute cardiac abnormality in 4 cases. 25 patients had echocardiogram for no new cardiac problem. In the latter group, the reason for requesting an echo was a cardiac murmur in 23 patients and extensive cardiac history in 2 cases. A specialist input from the cardiologist was sought in 5 cases. Most patients with aortic valve abnormality had surgery under general anaesthetic. No patient required cardiac surgery or balloon angioplasty pre-operatively. There was a significant delay to surgery in the patients who had a pre-operative echo (average 2.7 days, range 0–6 days) compared to ‘non-echo’ group (average 1.1 days, range 0–3 days), (P< 0.001). There was no significant difference in length of stay and mortality at 28 days between the two groups. We are now developing departmental guidelines for requesting echo in hip fracture patients with cardiac murmur to prevent unnecessary avoidable delay. We are developing a link with the cardiology department to expedite echocardiogram requests in hip fracture patients.

Study Design

An observational study in patients with congenital spinal deformity.

Background: Thumb carpalmetacarpal joint (CMCJ) osteoarthritis has been treated using various combinations of resection, interposition and replacement arthroplasties. The procedure of choice for various stages of CMCJ osteoarthritis remains controversial. This study compares the short term outcomes of trapeziectomy alone and trapeziectomy with PI2 implantation.

Methods: A cross-sectional observational study involving 33 patients (36 thumbs). 18 thumbs had trapeziectomy alone and 18 had trapeziectomy and PI2 implantation. Underlying indication was osteoarthritis in 35 thumbs and trauma in one thumb. Preoperative radiological assessment using the Eaton and Glickel grading for CMCJ osteoarthritis and clinical review including DASH and SF-36 score was performed at a mean follow-up of 18 months. Preoperative and postoperative pain level was assessed using Visual Analogue Scale (VAS) and satisfaction of the surgery using the Likert 5-point scale.

Results: There were 30 women and 3 men. The average age at follow up was 61 years (range 45 to 75). There was no significant difference between the two groups regarding age, duration of symptoms, and stage of disease, preoperative pain score and handedness. The mean DASH score at follow up was 26.8 for trapeziectomy alone group and 35.4 for the PI2 arthroplasty group. Preoperative to postoperative VAS for pain showed an improvement from fair to excellent in 60% of patients in trapeziectomy alone group and 30% of the patients in the PI2 arthroplasty group. There was no significant difference in the SF-36 scores between the two groups in all health domains. 6 out of 16(38 %) patients in the PI2 group had multiple surgeries mainly due to dislocation or subluxation of the implant. The overall Likert 5-point scale scores were highest for trapeziectomy alone group with 70% very satisfied compared to 40% in the PI2 arthroplasty group.

Conclusion: The early results of pyrocarbon PI2 arthroplasty show a high complication rate compared to simple trapeziectomy. The high rates of subluxation and dislocation observed in the early cohort resulting in multiple surgeries may be attributed to steep learning curve of the surgical technique and creation of a shallow groove for the implant. This may have contributed to the low satisfaction levels observed in PI2 arthroplasty group. Simple trapeziectomy provides satisfactory outcome in more than 80% of the patients.

Antibiotic prophylaxis aims to reduce wound and prosthetic infection, with minimal adverse effects. The 3 dose Cefuroxime regime is widely used, despite the risk of infective diarrhoea. We describe the results of single dose intraoperative Gentamicin and Amoxicillin compared to this standard regime.

We retrospectively reviewed 220 patients following hip hemiarthroplasty, creating 2 demographically matched cohorts; Group 1: 3 doses of Cefuroxime (n=113) and Group 2: single dose Gentamicin and Amoxicillin (n=107). End points were evidence of infection, length of stay and Clostridium difficile (CD) rates. results showed a significant reduction in group 2 for average length of stay (17 Vs. 13 days p=0.0432) and CD rates (7/113 Vs 0/107 p=0.0158).

Considering antibiotic therapies administered; significant reductions in group 2 for the number of patients that required post-operative antibiotics (99/113 Vs 73/107 p=0.0005), the median antibiotic DDDs (Defined Daily Doses) in 1st 2 post-operative days (0.25 Vs 0 p=0.0000) and those that received Ciprofloxacin or Cefuroxime post-operatively (82/113 Vs 24/107 p=0.0000). No significant difference was found for median antibiotic DDDs, median antibiotic DDDs from 2nd post-operative day, patients that received Flucloxacillin post-operatively.

Measured microbiological outcomes showed a significant reduction in the number of patients with confirmed growth requiring treatment with antibiotics in group 2 (21/23 Vs 12/22 p=0.0053). No difference was found between number patients with operation site swabbed and those with confirmed microbial growth.

We demonstrate single dose Gentamicin and Amoxicillin significantly reduces length of stay, CD rates and the number of patients requiring post-operative antibiotics for wound infection, inferring a reduction in the rate of wound infection. We would recommend this as an effective alternative to the 3 dose Cefuroxime regime.