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Bone & Joint Open
Vol. 4, Issue 1 | Pages 38 - 46
17 Jan 2023
Takami H Takegami Y Tokutake K Kurokawa H Iwata M Terasawa S Oguchi T Imagama S

Aims

The objectives of this study were to investigate the patient characteristics and mortality of Vancouver type B periprosthetic femoral fractures (PFF) subgroups divided into two groups according to femoral component stability and to compare postoperative clinical outcomes according to treatment in Vancouver type B2 and B3 fractures.

Methods

A total of 126 Vancouver type B fractures were analyzed from 2010 to 2019 in 11 associated centres' database (named TRON). We divided the patients into two Vancouver type B subtypes according to implant stability. Patient demographics and functional scores were assessed in the Vancouver type B subtypes. We estimated the mortality according to various patient characteristics and clinical outcomes between the open reduction internal fixation (ORIF) and revision arthroplasty (revision) groups in patients with unstable subtype.


Bone & Joint Research
Vol. 11, Issue 5 | Pages 270 - 277
6 May 2022
Takegami Y Seki T Osawa Y Imagama S

Aims

Periprosthetic hip fractures (PPFs) after total hip arthroplasty are difficult to treat. Therefore, it is important to identify modifiable risk factors such as stem selection to reduce the occurrence of PPFs. This study aimed to clarify differences in fracture torque, surface strain, and fracture type analysis between three different types of cemented stems.

Methods

We conducted biomechanical testing of bone analogues using six cemented stems of three different types: collarless polished tapered (CPT) stem, Versys Advocate (Versys) stem, and Charnley-Marcel-Kerboull (CMK) stem. Experienced surgeons implanted each of these types of stems into six bone analogues, and the analogues were compressed and internally rotated until failure. Torque to fracture and fracture type were recorded. We also measured surface strain distribution using triaxial rosettes.


Bone & Joint Open
Vol. 3, Issue 2 | Pages 165 - 172
21 Feb 2022
Kuwahara Y Takegami Y Tokutake K Yamada Y Komaki K Ichikawa T Imagama S

Aims

Postoperative malalignment of the femur is one of the main complications in distal femur fractures. Few papers have investigated the impact of intraoperative malalignment on postoperative function and bone healing outcomes. The aim of this study was to investigate how intraoperative fracture malalignment affects postoperative bone healing and functional outcomes.

Methods

In total, 140 patients were retrospectively identified from data obtained from a database of hospitals participating in a trauma research group. We divided them into two groups according to coronal plane malalignment of more than 5°: 108 had satisfactory fracture alignment (< 5°, group S), and 32 had unsatisfactory alignment (> 5°, group U). Patient characteristics and injury-related factors were recorded. We compared the rates of nonunion, implant failure, and reoperation as healing outcomes and Knee Society Score (KSS) at three, six, and 12 months as functional outcomes. We also performed a sub-analysis to assess the effect of fracture malalignment by plates and nails on postoperative outcomes.


The Bone & Joint Journal
Vol. 95-B, Issue 10 | Pages 1392 - 1395
1 Oct 2013
Matsumoto T Imagama S Ito Z Imai R Kamada T Shimoyama Y Matsuyama Y Ishiguro N

The main form of treatment of a chordoma of the mobile spine is total en bloc spondylectomy (TES), but the clinical results are not satisfactory. Stand-alone carbon ion radiotherapy (CIRT) for bone and soft-tissue sarcomas has recently been reported to have a high rate of local control with a low rate of local recurrence.

We report two patients who underwent TES after CIRT for treating a chordoma in the lumbar spine with good medium-term outcomes. At operation, there remained histological evidence of viable tumour cells in both cases. After the combination use of TES following CIRT, neither patient showed signs of recurrence at the follow-up examination. These two cases suggest that CIRT should be combined with total spondylectomy in the treatment of chordoma of the mobile spine.

Cite this article: Bone Joint J 2013;95-B:1392–5.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 12 | Pages 1638 - 1645
1 Dec 2011
Kanemura T Ishikawa Y Matsumoto A Yoshida G Sakai Y Itoh Z Imagama S Kawakami N

We evaluated the maturation of grafted bone in cases of successful fusion after a one- or two-level posterior lumbar interbody fusion (PLIF) using interbody carbon cages. We carried out a five-year prospective longitudinal radiological evaluation of patients using plain radiographs and CT scans. One year after surgery, 117 patients with an early successful fusion were selected for inclusion in the study. Radiological evaluation of interbody bone fusion was graded on a 4-point scale. The mean grades of all radiological and CT assessments increased in the five years after surgery, and differences compared to the previous time interval were statistically significant for three or four years after surgery. Because the grafted bone continues to mature for three years after surgery, the success of a fusion should not be assessed until at least three years have elapsed. There were no significant differences in the longitudinal patterns of grafted bone maturity between iliac bone and local bone. However, iliac bone grafting may remodel faster than local bone.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 8 | Pages 1084 - 1087
1 Aug 2011
Tauchi R Imagama S Kanemura T Yoshihara H Sato K Deguchi M Kamiya M Ishiguro N

We reviewed seven children with torticollis due to refractory atlanto-axial rotatory fixation who were treated in a halo vest. Pre-operative three-dimensional CT and sagittal CT imaging showed deformity of the superior articular process of C2 in all patients. The mean duration of halo vest treatment was 67 days (46 to 91). The mean follow-up was 34 months (8 to 73); at the latest review six patients demonstrated remodelling of the deformed articular process. The other child, who had a more severe deformity, required C1-2 fusion.

We suggest that patients with atlanto-axial rotatory fixation who do not respond to conservative treatment and who have deformity of the superior articular process of C2 should undergo manipulative reduction and halo-vest fixation for two to three months to induce remodelling of the deformed superior articular process before C1-2 fusion is considered.


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 3 | Pages 393 - 400
1 Mar 2010
Imagama S Matsuyama Y Yukawa Y Kawakami N Kamiya M Kanemura T Ishiguro N

We have reviewed 1858 patients who had undergone a cervical laminoplasty and identified 43 (2.3%) who had developed a C5 palsy with a MMT (MRC) grade of 0 to 2 in the deltoid, with or without involvement of the biceps, but with no loss of muscular strength in any other muscles. The clinical features and radiological findings of patients with (group P; 43 patients) and without (group C; 100 patients) C5 palsy were compared. CT scanning of group P revealed a significant narrowing of the intervertebral foramen of C5 (p < 0.005) and a larger superior articular process (p < 0.05). On MRI, the posterior shift of the spinal cord at C4–5 was significantly greater in group P, than in group C (p < 0.01).

This study is the first to correlate impairment of the C5 nerve root with a C5 palsy. It may be that early foraminotomy in susceptible individuals and the avoidance of tethering of the cord by excessive laminoplasty may prevent a post-operative palsy of the C5 nerve root.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 431 - 431
1 Aug 2008
Yoshihara H Kawakami N Matsuyama Y Imagama S Gang F Ishiguro N
Full Access

It is accepted that the development of scoliosis has a close relationship with physical growth, but the aetiology and mechanism of the disease remain unknown. Few studies have assessed the bone microarchitecture and histomorphological findings in vertebrae. After the occurrence of scoliosis, those include secondary changes caused by mechanical compression. It is important to investigate those data in the period prior to the occurrence of scoliosis.

Methods: Study One: One hundred female Broiler chickens were divided into 3 groups: the control group (n=20), the sham operation group (n=20), and the pine-alectomy group (n=60). Then the pinealectomy group was divided into three groups according to the time of sacrificing: one week after the operation (Group P-1w, n=20), two weeks and three weeks after the operation respectively (Group P-2w and 3w, n=20 respectively). Using microCT, the bone volume (BV/TV), trabecular thickness (Tb.Th), the number of trabecular (Tb.N), and trabecular separation (Tb.Sp) of the concave and convex sides of the apex vertebrae in the scoliotic chickens were determined.

Study Two: Sixty female Broiler chickens were divided into three groups: the control group (group C, n=20), the sham operation group (group S, n=20), and the pinealectomy group (group P, n=20). Each group was then subdivided into two groups according to the time of sacrificing: 3 days after the operation (group 3-C, 3-S, 3-P, n=10), and six days after the operation (group 6-C, 6-S, 6-P, n=10). Decalcified thin sagittal sections were made using a tartrate-resistant acid phosphatase (TRAP) stain. Histological examinations of the growth plate, trabecular structure and osteoclast number were performed.

Results: Study One: The incidences of scoliosis in the pine-alectomised Broiler chickens was 84.2% (Group P-1w), 88.9% (Group P-2w) and 89.5% (Group P-3w) respectively, and Cobb angles were averaged 11.6, 14.6 and 21.2 degrees respectively. There was no obvious wedging deformity of vertebrae in the groups. Only in Group 3w, the BV/ TV, Tb.Th and Tb.N of the concave side were significantly greater than those of the convex side.

Study Two: Nine out of ten chickens in group 6-P showed scoliosis deformity, while the presence of scoliosis was unclear in any of chickens in group 3-P. The osteoclast number increased significantly in group 3-P, compared to groups 3-C and 3-S, and the trabecular thickness was greater in group 3-P than in groups 3-C and 3-S. There was no significant change in the growth plate or in other aspects of the trabecular structure, except for trabecular thickness, in any of the groups.

The results of study one showed that the change of microarchitecture might be caused by Wolff’s law and was the secondary response to the scoliotic deformity. Therefore, it was difficult to clarify the cause of scoliosis using micro CT. In study 2 we found that the number of osteoclast increased in pinealectomised chickens after 3 days postoperatively, just before scoliosis began to develop. We also found there was no change in the growth plate. These outcomes suggest that there are no relationships between changes in the growth plate and the development of scoliosis. However, the change in osteoclast number may have a relationship with the development of scoliosis through changes in bone modelling.