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Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_6 | Pages 33 - 33
1 Feb 2016
Breen A Mellor F Breen A Hilton A
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Purpose and Background:

Despite the rise of back pain disability, objective mechanical assessment is generally lacking. Quantification of intervertebral kinematics using fluoroscopy provides objective measurement, but its use in clinical practice has not been assessed. This study reviewed cases referred to one UK site for lumbar spine quantitative fluoroscopic (QF) examinations and compared the reasons for referral with the findings reported.

Methods and Results:

Fifty-seven consecutive referrals were reviewed. Patients underwent passive recumbent and/or weight-bearing active examinations in either the sagittal or both the sagittal and coronal planes. Data were extracted from anonymised QF reports and analysed for patient characteristics, reason for referral, working diagnosis at referral, level(s) of interest, previous surgical procedures and findings reported. Reports were also thematically analysed for key findings.

Most patients had chronic back conditions of moderate or severe intensity. Most (38/57) were male, mean age 47 (SD 13.1) and mean complaint duration 5.4 years (0.3–32 years). They were referred mainly to investigate segmental instability (19/54) or spondylolisthesis (13/54) to inform either surgical referral or conservative management. Instability was reported in only 8/57 cases, but restricted and hypermobile levels in the same patient was also common (13/57). In 11 cases no mechanical abnormality was found.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 42 - 42
1 Apr 2012
Stenning M Hilton A
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It was noted that in our spinal theatre a constant cause of delay was lack of an available radiographer. This work describes our solution to this problem by training theatre staff to operate the imaging equipment for the simple single plane images required in spinal surgery.

Under the guidance of the trust's Radiation Protection Advisor to a training program for theatre staff was devised that encompassed the practical aspects of using the imaging equipment and the theoretical elements of radiation safety. All changes in practice complied with the radiation safety regulations IRR 99 and IRMER 2000.

The trained staff now work as independent operators in the spinal theatre. They work to a ridge protocol and have to report directly to a Radiation Protection Supervisor (senior radiographer) at the end of each list so that the images taken and radiation dosage can be verified.

Since the change of practice, the spinal theatre has been more efficient, performing up to one major case extra per list. The radiology department has benefited by having a radiographer freed to perform more complex procedures elsewhere. The operators have also commented on how they have found the whole process rewarding both professionally and personally.

The training of theatre staff to operate the imaging equipment in our spinal theatre has been a successful endeavour and at present the trust is currently planning to expand the program to include other surgical fields such as urology and laparoscopic surgery.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 378 - 379
1 Jul 2010
Barham G Hilton A
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The study was designed to quantify the hit/miss ratio of non-radiologically assisted caudal epidurals, assessing both accuracy of entry into the epidural space and adequacy flow of contrast and therapeutic agents to the level of pre-defined pathology.

We studied 146 consecutive patients listed for a caudal epidural under sedation for either radicular pain or spinal stenosis. When the surgeon was happy with placement of the needle its position was assessed using image intensifier and injection of radio-opaque dye (Omnipaque). The epidurogram was also used to confirm the level of pathology had been reached by the steroid and local anaesthetic.

Three patients were excluded because of inadequate records. Five patients did not attend for their procedure. Of the remaining 138 patients Consultant spinal surgeons carried out 75 procedures and the remaining 63 cases were performed by “middle grade” surgeons. 36 of 138 patients (26%) had placement of spinal needle outside the epidural space after first blind placement. Hit rate was not related to surgeon grade, patient age or patient diagnosis. In 6% of cases the radio-opaque dye did not reach the level of documented pathology had been reached by the dye. 2 patients had a “spinal” pattern of block requiring overnight admission, there were no other complications recorded.

A miss rate of 26% in the blind placement of spinal needles through the sacral hiatus in caudal epidurals is unacceptable. We would therefore recommend position of the needle is confirmed radiologically and epidurogram is used to confirm accurate delivery of the therapeutic agents.

Interest statement: none

Ethics approval: none (study of current practice)


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 189 - 190
1 Mar 2006
David L Hilton A Back D Cobb J Cannon S Briggs T
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Introduction: Malignant tumours of the fibula are rare and can be difficult to treat. We discuss the management and outcome of 52 patients who presented with malignant tumours of the fibula over a 15-year period between 1983 and 1998.

Methods: Data was collected prospectively and reviewed from the Bone Tumour database, medical records and by clinical review. Consecutive patients were studied and survival was calculated using the Kaplan-Meier curve.

Patients: The tumour type was Osteosarcoma (23 patients), Ewing’s sarcoma (16), Chondrosarcoma (11 – of which 10 low grade) and Malignant Fibrous Histiocytoma (2). We concentrate on the two most common frankly malignant groups: Osteosarcoma and Ewing’s. The male:female ratio of patients with Osteosarcoma was 11:12 and with Ewing’s Sarcoma was 11:5. Mean age for Osteosarcoma was 21.5 years and for Ewing’s Sarcoma was 14.2. The most common site of tumour was in the proximal fibula in both Osteosarcoma (19 / 23) and Ewing’s Sarcoma (10 / 16). The stage of disease at presentation was IIa or IIb in the majority of patients, with seven patients presenting with metastases.

Management: The current investigative procedures are Radiographs, Magnetic Resonance Imaging, Radioisotope Bone Scans, Computerised Tomography of the chest and needle biopsy whereas in the past CT of the lesion and open biopsy were common. Chemotherapy was administered as per protocol at the time of diagnosis and radiotherapy was given in selected cases. Surgery was performed on all but 3 patients, who were unfit and died. This consisted of local en bloc resection in 86.3% and above knee amputation in 6.8%.

Outcome: Whereas all the diaphyseal and distal lesions were completely excised, 9 out of 26 proximal lesions had a marginal excision, 4 of which had open biopsies. The common peroneal nerve was sacrificed in 50% of cases and this had no link to survival. The overall 5-year survival was 33% for Osteosarcoma and 40% for Ewing’s Sarcoma, with proximal lesions doing much worse than diaphyseal and distal lesions. Patients who had marginal excisions all died within 2.5 years.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 298 - 298
1 Sep 2005
Hilton A David L Briggs T Cobb J Cannon S
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Introduction and Aim: This project reports on patients treated with malignant fibula pathology at the London Bone Tumor Service with the aim of reporting on the prognosis for such patients.

Method and Results: Over a 15-year period, The London Bone Tumor Service has treated 39 patients with malignant fibula pathology: Osteosarcoma (23), Ewing’s sarcoma (16). Proximal fibula pathology was more common (29), distal (five) and diaphyseal (five). Thirty-two patients were treated with wide local excision initially, one below knee amputation, three above knee amputations, two were not fit for surgery and two died while receiving chemotherapy. Two patients required subsequent above knee amputations and one patient a hip disarticulation. Relapse was very common in proximal fibula osteosarcoma. Only 7/23 patients avoided both metastasis and local recurrence.

The five-year survival rate of osteosarcoma of the proximal fibula is 33%, distal fibula 100% and diaphyseal 100%. Ewing’s sarcoma of the proximal fibula is 40%, diaphyseal 50% and distal fibula 100%.

Conclusion: Despite relatively early presentation of symptoms, the prognosis of proximal fibula osteosarcoma and Ewing’s remains poor. Unlike the prognosis of both distal and diaphyseal pathology, which remains excellent.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 261 - 261
1 Mar 2003
Eastwood D Back D Hilton A Black C
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Purpose: To review the orthopaedic manifestations and document the results of surgical intervention. Material and Methods: A review of all 22 children currently attending a specialist scleroderma clinic was performed. Disease extent was measured in terms of percentage body surface area (BSA) affected and all orthopaedic abnormalities were documented. The outcome of surgical intervention was evaluated.

Results: All children presented by the age of 12 and all but 2 had developed joint contractures of either the lower or upper limbs affecting function within 2yrs of diagnosis. Overall, lower limbs were more commonly affected than upper. Abdominal scleroderma led to a scoliosis in 75% of cases. The mean BSA affected was 35% (range 5-65%) with contractures more related to site of disease rather than extent. Pain was associated with lower limb contractures and loss of function with hand contractures. Limb length discrepancy (LLD) was common with a mean of 3cms (range 2-6.5cms). 8 children have had surgery. 7 developed wound healing problems. 50% of operations failed to correct the deformity and in a further 25% relapse has occurred. In the remaining 2 cases a good result was achieved. In addition, one epiphysiodesis has been performed and 3 are planned.

Conclusions: This is the largest known review of children with linear scleroderma. Joint contractures are common but poorly managed by conservative methods alone. Surgical intervention is difficult but early defini-tive treatment is recommended with subsequent aggressive splinting during growth whilst the disease is active. LLD must be corrected.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 113 - 113
1 Feb 2003
Hilton A David L Back DL Cannon SR Cobb J Pringle J Briggs TWR
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We discuss the management and outcome of 52 patients who presented with malignant tumours of the fibula over a 15-year period between1983 and 1998.

The tumour type was Osteosarcoma (23 patients), Ewing’s sarcoma (16), Chondrosarcoma (11 – of which 10 low grade) and Malignant Fibrous Histiocytoma (2). We concentrate on the two most common frankly malignant groups: Osteosarcoma and Ewing’s.

The male:female ratio of patients with Osteosarcoma was 11:12 and with Ewing’s Sarcoma was 11:5. Mean age for Osteosarcoma was 21. 5 years and for Ewing’s Sarcoma was 14. 2. The most common site of tumour was in the proximal fibula in both Osteosarcoma (19 / 23) and Ewing’s Sarcoma (10 / 16). The stage of disease at presentation was IIa or IIb in the majority of patients, with seven patients presenting with metastases.

The current investigative procedures are Radiographs, Magnetic Resonance Imaging, Radioisotope Bone Scans, Computerised Tomography of the chest and needle biopsy whereas in the past CT of the lesion and open biopsy were common. Chemotherapy was administered as per protocol at the time of diagnosis and radiotherapy was given in selected cases.

Surgery was performed on all but 3 patients, who were unfit and died. This consisted of local en bloc resection in 86. 3% and above knee amputation in 6. 8%. Whereas all the diaphyseal and distal lesions were completely excised, 9 out of 26 proximal lesions had a marginal excision, 4 of which had open biopsies. The common peroneal nerve was sacrificed in 50% of cases and this had no link to survival.

The overall 5-year survival was 33% for Osteosarcoma and 40% for Ewing’s Sarcoma, with proximal lesions doing much worse than diaphyseal and distal lesions. Patients who had marginal excisions all died within 2. 5 years.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 32 - 32
1 Jan 2003
Back D Hilton A Espag M Canon S Briggs T
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100 pre-operative and post-operative knee and function scores were analysed to assess whether a low pre-operative score was related to a poorer outcome, ie, are we operating too late? A two tailed student “t” test was performed showing that a pre-operative “function “ score of less than 30, resulted in a lower post-operative “function” score and the difference was statistically significant. These patients also showed the greatest improvement in scores and were the most satisfied with surgery. However, a low pre-operative “knee” score could not be related to a low post-operative “knee” score. Patients who had either a “knee” or “function” score of greater than 60 made no statistically significant improvement in either score. In conclusion, the pre-operative “knee” score is not a reliable indicator for when to perform surgery. However, the “pre-operative “ function score should be given more credence, along with clinical judgement, as it would appear that operating too late adversely affects the functional outcome of total knee arthroplasty.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 32 - 32
1 Jan 2003
Hilton A Back D Espag M Briggs T Cannon S Wakeman R
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65 patients over the age of 80 years, who underwent a total knee arthroplasty between 1989 and 1994, were retrospectively reviewed, by means of questionnaire, phone call, clinical and radiological examination.Notes were reviewed for pre-existing medical conditions, pre-operative and post-operative Knee Society “Knee” and “Function” scores. They were then compared with 65 randomly selected patients in a different age group, 70 years and under.56 octogenarians were alive at 5 years and 50 available for full review.

Elderly patients had more pre-existing medical conditions, with hypertension a ubiquitous diagnosis, required a longer in patient stay and more social services input before discharge, than the younger age groups. All patients in the elderly group suffered from osteoarthritis, unlike the younger age groups. Valgus deformity of the knees was only seen in the younger cohort. Previous surgery was more common in the octogenarians, with more octogenarians having undergone a tibial osteotomy and more youngsters undergoing arthroscopy. A reflection of changing surgical practice.

“Knee” Scores were not significantly different between the age groups. However, the “function “ scores pre-operatively, were significantly lower in the over 80s and they made a more significant post-operative gain. Post-operatively, elderly male patients were more likely to go into retention post-operatively, than female patients and males in the younger age group.

None of the prostheses had required revision in the elderly age group and only 5 patients had died since the surgery. None of the deaths were related to the surgery.

We recommend pre-operative catheterisation of octogenarian patients, especially those with a history of prostatism. There would appear to be from this review no indication for denying elderly patients an arthroplasty on the basis of age.


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 3 | Pages 359 - 363
1 Apr 2001
Back DL Cannon SR Hilton A Bankes MJK Briggs TWR

We reviewed the outcome of 422 primary cemented Kinemax total knee arthroplasties implanted into 369 patients over a period of five years, from January 1989. The operations were carried out at two NHS district general hospitals and one teaching hospital by 31 surgeons. During the period of review, 49 patients died and ten knees were lost to follow-up (68 knees). The mean Knee Society score improved from 28 before to 89 after surgery, and the mean function score increased from 23 to 79. The range of flexion improved from 92° to 105°.

These improvements were maintained throughout the period of study. At the latest review radiolucent lines of 1 mm were seen around 15% of tibial components, 1.4% of patellar components and 9.5% of femoral components. In no case were these changes progressive. Using revision as the endpoint, cumulative survival was 99% after five years and 96.95% after nine years. All revisions were undertaken for deep infection or secondary trauma.

Our study has shown that the Kinemax total knee replacement, when carried out with retention of the posterior cruciate ligament by surgeons of varying experience, produces very satisfactory results in the medium term.