Management and outcomes of fungal periprosthetic joint infection (PJI) remain unclear due to its rarity. Although two-stage exchange arthroplasty is considered a treatment of choice for its chronic features, there is no consensus for local use of antifungal agent at the 1st stage surgery. The purpose of this study was to evaluate the efficacy of antifungal-impregnated cement spacer in two-stage exchange arthroplasty against chronic fungal PJIs after total knee arthroplasty (TKA). Nine patients who were diagnosed and treated for chronic fungal PJIs after TKA in a single center from January 2001 to December 2016 were enrolled. Two-stage exchange arthroplasty was performed. During the 1st stage resection arthroplasty, amphotericin-impregnated cement spacer was inserted for all patients. Systemic antifungal medication was used during the interval between two stage operations. Patients were followed up for more than 2 years after exchange arthroplasty and their medical records were reviewed.Purpose
Methods
Rotational alignment is important for the long-term success and good functional outcome of total knee arthroplasty (TKA). While the surgical transepicondylar axis (sTEA) is the generally accepted landmark on the distal femur, a precise and easily identifiable anatomical landmark on the tibia has yet to be established. Our aim was to compare five axes on the proximal tibia in normal and osteoarthritic (OA) knees to determine the best landmark for determining rotational alignment during TKA. One hundred twenty patients with OA knees and 30 without knee OA were recruited for the study. Computed tomography (CT) images were obtained and converted through multiplanar reconstruction so the angles between the sTEA and the axes of the proximal tibia could be measured. Five AP axes were chosen: the line connecting the center of the posterior cruciate ligament(PCL) and the medial border of the patellar tendon at the cutting level of the tibia (PCL-PT), the line from the PCL to the medial border of the tibial tuberosity (PCL-TT1), the line from the PCL to the border of the medial third of the tibia (PCL-TT2), the line from the PCL to the apex of the tibia (PCL-TT3), and the AP axis of the tibial prosthesis along with the anterior cortex of the proximal tibia (anterior tibial curved cortex, ATCC).Background
Methods
Buechel and Pappas invented a modified version of LCS RP system (Co-Cr) with light material (Titanium), axial rotation limiting bar and improved conformity. The purpose of this prospective randomized study was to compare the minimum 3-year clinical outcomes including lightness, preference, and instability between the Co-Cr implant system and the Titanium implant system in bilateral total knee arthroplasty. We prospectively enrolled 108 patients and 20 patients were lost to follow-up. Therefore, 88 patients (176 knees; mean age, 69.9±6.0years) were included in the study. The range of motion and clinical scores such as Knee Society score (KSS), Hospital for Special Surgery score (HSS) and Western Ontario and McMaster University (WOMAC) scores were measured preoperatively and postoperatively. At each follow-up, patients also complete a Likert scale questionnaire regarding subjective pain, lightness, left-right side preference (naturalness and satisfaction) and subjective instability. There were no significant differences in all preoperative variables between two groups (p>.05). Mean follow-up period was 46.3±8.8 (36 to 72) months. The mean weight of Titanium implants was three times lighter than that of Co-Cr implants (133.9g versus 390.1g, p<.01). At the minimum of 3-year follow-up, there were no significant differences in pain, range of motion (ROM), clinical scores including KSS, HSS, and WOMAC between both groups. Also, the study showed no significant differences with subjective pain, lightness, preference (convenience, naturalness, and satisfaction), and subjective instability between the Co-Cr protheses and the Titanium protheses (p>.05). No differences in clinical outcomes as well as subjective side-to-side differences between the Co-Cr prostheses and the Titanium prostheses were observed in the minimum 3-year follow-up. This implies that patients do not feel differently with two different weighted implants in mid-term follow-up.
The purpose of this study was to determine whether the patient's perceived outcome and speed of recovery differs between a posterior cruciate ligament (PCL) substituting (cam-post type) and PCL sacrificing (ultracongruent polyethylene) total knee arthroplasty (TKA). Thirty eight patients (mean age, 65 years) underwent bilateral TKA using a PCL substituting and a PCL sacrificing prosthesis on each side. At each follow-up, the stability of anteroposterior and mediolateral laxity using stress radiographs, range of motion, quadriceps muscle power recovery using isokinetic dynamometer and radiographs were evaluated. At the 1-year evaluation, we asked, “Which is your better knee overall?” to determine the patients' preferences.Introduction
Methods
The long-term outcome and survivorship of TKA in Asian countries have been reported to be excellent, comparable to Western countries. However, increased knee flexion is required for many daily activities in Asian cultures, which remains a major problem to be resolved. High-flexion TKA designs have been introduced to improve flexion after TKA and to allow a high degree of flexion in a safe manner. However, several biomechanical studies have shown that high-flexion designs have a greater risk for the loosening of the femoral component compared to the conventional TKA designs. We evaluated the implant survival and the mid-term clinical and radiological outcomes of Asian patients who had undergone high-flexion TKA and assessed whether high-flexion activities increased the risk of premature failure. We prospectively followed 72 Nexgen LPS-flex fixed TKA in 47 patients implanted by a single surgeon between March 2003 and September 2004. Five patients (6 knees) expired during follow-up. A Kaplan-Meier survivorship analysis using revision surgery as the end point was used to determine the probability of survival for the cohort and the equality of survival between two subgroups who could perform high-flexion activities or not. Median follow-up was 6.5 (0.9–8.6) years. Twenty-five patients (33 knees) received a revision for aseptic loosening of the femoral component at a mean of 3.5 years (range, 0.9–7.8 years). According to the Kaplan-Meier survivorship analysis, the probabilities of survival without revision for aseptic loosening are 66.7% and 51.8% at 5 and 8 years, respectively. The 8-year cumulative survivorship is lower (30.6%) when squatting, kneeling, or sitting cross-legged could be achieved than if none of these activities were possible (78.3%). In the surviving knees, non-progressive radiolucent lines were observed around the femoral component of 12 patients (15 knees) and one tibial component. The overall mid-term high-flex implant survival of our Asian cohort is lower than that of the conventional and other high-flexion designs. This unacceptable high rate of femoral component loosening is strongly associated with postoperative high flexion activities.
