Patients with above knee amputation (AKA) often experience poor socket fit exacerbated by minor weight changes, sweating, and skin problems. A transcutaneous, press-fit distal femoral intra-medullary device was designed in 1999, such that the distal external aspect serves as a hard point for AKA prosthesis attachment. The implant is placed in a retrograde fashion, followed 6-8 weeks later by stomatisation and connected via direct extention to an AKA prosthesis.

Thirty-seven patients with 39 limbs (30 males, 7 females) underwent two-stage prosthesis implantation with the Endo-Exo Femurprosthesis (EEFP) in Germany between 1999 and January 2008. Their indications for surgery were persistent AKA prosthesis socket difficulties with absence of major comorbid physical or mental illnesses. The patients were followed clinically and radiographically for a minimum of 2 years. Assessments included patient satisfaction ratings, functional surveys, pain scores, and oxygen consumption.

Fifty-four percent of patients needed at least one revision (20/37); 80% were minor (16/20) and 20% were major (4/20). Most of the minor revisions were due to soft tissue stomal irritation and occurred prior to a design change in the prosthesis. 2 patients sustained traumatic, peri-trochanteric fractures that were treated operatively proximal to the implant, with retention of the implant. 4 implants were explanted due to infection or prosthesis fracture and 2 of these (50%) were later reimplanted successfully. Overall, 94.9% (37/39) limbs had ultimate EEFP implant success. All functional assessments showed statistically significant improvement over baseline except oxygen consumption, which trended toward improvement.

This procedure demonstrated a high degree of functional improvement for the majority of AKA patients treated. Despite an initially high revision rate, the EEFP prosthesis achieves an extremely high rate of successful reconstruction for trans-femoral amputees when more traditional options have failed and therefore warrants further scientific study.