Introduction: Autologous chondrocyte implantation was introduced in 1994 by Brittberg and Peterson for the treatment of large full-thickness focal chondral defects. The purpose of the present study was to evaluate the mid-term results of this technique in a group of patients with post-traumatic chondral defects of the knee.

Materials and Methods: Fifteen patients underwent autologous chondrocyte implantation between 2001 and 2006 and were prospectively assessed preoperatively, at 3, 6, 9, 12 months, 3.5 years and last follow-up with use of standard rating scales (IKDC subjective score, pain Visual Analogic Scale (VAS), Brittberg and Peterson’s score). The inclusion’s criteria were: pain VAS more than 40/100, age between 18 and 50 years, focal chondral defect in weight bearing area grade 3 or 4 and informed and signed consent. Patients with varus or valgus deformities with malalignement more than 5 degrees, knee instabilities and signs of arthritis on radiographs were excluded. The same experienced surgeon performed all the procedures.

Results: Fourteen patients were reviewed at the latest follow-up. The mean age of the patients at the time of autologous chondrocyte transplantation was 37.7 years (range, 30 to 45). The mean duration of symptoms was 2.9 years (0.5 to 7). Nine patients (83%) had previous operations on the index knee. The defect was located on the medial femoral condyle in 11 patients and on the lateral femoral condyle in 3. The mean lesion size was 1.80 cm² (range, 1.5 to 3.5 cm²) after débridement. After a mean duration of follow-up of 6 years (3.3–7.8), 84% of the patients had improvement on a patient self-assessment questionnaire. The IKDC subjective score and Brittberg-Peterson’s score were all improved. The mean IKDC subjective score increased from 40 (27.6–65.5) preoperatively to 60.2 (35.6–89.6) at the latest evaluation. The mean pain VAS decreased from 66.3 (44–89) to 23.2 (0–77). The Brittberg and Peterson’s score decreased from 54.4 (11.8–98.2) to 32.9 (0–83.9). Two patients (16.7%) felt no improvement by the chondrocyte transplantation at the last follow-up. Two complications occurred: graft periosteum hypertrophy treated by débridement and a pulmonary embolus.

Discussion: Our results are similar than those reported in the literature. These outcomes are encouraging and need further follow-up to confirm the long-term efficacy of autologous chondrocyte implantation.

Purpose of the study: The iliopsoas bursa lies immediately anteriorly to the hip joint capsule and in certain cases there exists a natural communication between a hip prosthesis and the iliopsoas bursa, enabling formation of an inguinal mass by distension of the bursa.

Material and methods: We report six cases of a pseudo-tumoral mass which developed in the femoral scarpa triangle revealing a complication of total hip arthroplasty. These six patients, aged 66–79 years had their prosthesis for 11.5 years on average (range 4–20 years). Three had a history of acetabular dysplasia. All complained of pain. Five patients presented a palpable mass in the inguinal region. Two patients underwent emergency surgery, one for suspected strangulation of a crural herniation and the second for septic inguinal adenopathy. In two patients the clinical presentation was related to the local effect of the mass: lower limb edema with recurrent phlebitis due to venous and lymphatic compression, and femoralgia due to compression of the femoral nerve. The underlying prosthetic complications were: aseptic loosening (n=4), polyethylene wear (n=2), infection (n=1). All patients underwent revision surgery to change the prosthesis. The cystic formation was drained without resection. Symptoms resolved after replacement surgery in all patients.

Discussion: Palpation of an inguinal mass with signs of local compression in a patient with a painful total hip arthroplasty is a sign of a prosthetic complication (infection, loosening, wear). The diagnostic work-up should include bacteriology and plain x-rays of the hip joint. Bone scintigraphy may be contributive. Arthrography can demonstrate presence of a communication. Computed tomography provides the best visualization of the mass and its relations with neighboring organs. A duplex-Doppler is needed in all cases to search for thromboembolic complications prior to surgery. We chose not to resect the cystic formation in our patients, preferring treatment of the intra-articular cause. The fact that the mass and local its effects resolved in all cases with no recurrence at last follow-up leads us to recommend this attitude for typical presentations.