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Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_4 | Pages 14 - 14
1 Jan 2013
Mannion A Fekete F Kleinstueck F Mutter U Lattig F Porchet F Jeszenszky D Grob D
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Background

Recent years have witnessed a paradigm shift in the assessment of outcome in spine surgery, with patient-centred questionnaires replacing traditional surgeon-based assessments. The assessment of “complications” — loosely defined as new/unexpected problems arising as a result of surgery — has not enjoyed this same enlightened approach.

Methods

Patients with lumbar degenerative disorders operated with the goal of pain relief, completed a questionnaire 1 year post-operatively enquiring about complications arising as a consequence of their operation. They rated the bothersomeness of any such complications on a 5-point adjectival scale. Global outcome of surgery and satisfaction were rated on 5-point Likert scales.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 10 | Pages 1347 - 1353
1 Oct 2009
Grob D Bartanusz V Jeszenszky D Kleinstück FS Lattig F O’Riordan D Mannion AF

In a prospective observational study we compared the two-year outcome of lumbar fusion by a simple technique using translaminar screws (n = 57) with a more extensive method using transforaminal lumbar interbody fusion and pedicular screw fixation (n = 63) in consecutive patients with degenerative disease of the lumbar spine. Outcome was assessed using the validated multidimensional Core Outcome Measures Index. Blood loss and operating time were significantly lower in the translaminar screw group (p < 0.01). The complication rates were similar in each group (2% to 4%). In all, 91% of the patients returned their questionnaire at two-years. The groups did not differ in Core Outcome Measures Index score reduction, 3.6 (sd 2.5) (translaminar screws) vs 4.0 (sd 2.8) (transforaminal lumbar interbody fusion) (p = 0.39); ‘good’ global outcomes, 78% (translaminar screws) vs 78% (transforaminal lumbar interbody fusion) (p = 0.99) or satisfaction with treatment, 82% (translaminar screws) vs 86% (transforaminal lumbar interbody fusion) (p = 0.52).

The two fusion techniques differed markedly in their extent and the cost of the implants, but were associated with almost identical patient-orientated outcomes.

Extensive three-point stabilisation is not always required to achieve satisfactory patient-orientated results at two years.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 440 - 440
1 Sep 2009
Grob D Mannion A Bartanusz V Kleinstück F Lattig F Jeszenszky D Dvorak J Porchet F
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Introduction: Recent years have witnessed something of a paradigm shift in relation to the assessment of outcome in spine surgery: multidimensional patient-centred questionnaires have superseded the traditional surgeon-based rating of global outcome, and surgical registries have been developed to capitalise on the principle of “strength in numbers”. Interestingly, although recognised as a potential determinant of the patient’s view of the success of the surgery, the assessment of complications — in this context defined as new or unexpected problems arising as a result of surgery — has not enjoyed the same enlightened approach in relation to the patient’s perspective. The present study sought to fill this gap in the current array of outcome measures.

Methods: All German-speaking patients undergoing spinal surgery within our Spine Unit in the two years from Jan 2005 to Dec 2006 were asked to complete the patient-orientated Core-Measures-Index of the SSE Spine Tango Spine Surgery Registry 12 mo after surgery; the surgeon completed a Spine Tango surgery form and follow-up forms at various intervals up to 12 mo postop. In the patient questionnaire, the patient was asked “did any complications arise as a consequence of your operation 1 year ago (e.g. problems with wound healing, paralysis, sensory disturbances, etc.)? If so, give details.” Patients were also asked about their satisfaction with the operation and the global outcome of surgery.

Results: 2080/2259 (92%) patients returned a 12-month questionnaire. 28% patients answered “yes” to the complications question. This compares with complication rates of 3–10% recorded during the various Spine Tango Surgical follow-ups up to 12 months post-op. Patients sometimes listed “complications” that would rarely classify as such in the traditional sense; however, the incidence of their reported complications was significantly associated with outcome/satisfaction, suggesting they were not trivial to the patient. The more recent addition of a question concerning the “bothersomeness” of the reported complications revealed that 6% patients thought the complications were not at all bothersome; 21%, slightly bothersome; 30%, moderately bothersome; 27%, very bothersome and 16%, extremely bothersome.

Discussion: The results indicate that, just like outcome, “complications” should be assessed from both the patient’s and the surgeon’s perspectives, not least to better understand the reasons accounting for dissatisfaction and a poor patient-rated outcome.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 439 - 439
1 Sep 2009
Grob D Mannion A Bartanusz V Jeszenszky D Kleinstück F Lattig F
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Introduction: Fusion is typically indicated for degenerative spinal disorders with concomitant instability or painful spondylosis. Numerous techniques are used, with considerable variation in their invasiveness, risks and costs, although few can boast superiority for a given indication, particularly in relation to patient-orientated outcomes. This cohort study compared outcomes after fusion with translaminar screws (TS) versus transforaminal lumbar interbody fusion plus pedicular fixation (TLIF) plus pedicular fixation (both with decompressive procedures).

Methods: The study was nested within our SSE Spine Tango data acquisition system. The suitability (or otherwise) for inclusion of every Spine Unit patient was indicated at the pre-operative consultation. Inclusion criteria: mono/bisegmental degenerative disc disease, facet syndrome or degenerative spondylolisthesis; German language; no previous surgery (except discectomy). Each surgeon consistently used his pre-stated, preferred method (TS or TLIF) for all his patients fitting the inclusion criteria. Before and 12 and 24 months post-surgery, patients completed the multidimensional Core Outcome Measures Index (COMI; 0–10 scale); after 12-months, global outcome was rated on a Likert-scale and dichotomised into “good” and “poor” groups.

Results: 121 patients took part; 57 in the TS group (1 surgeon) and 64 in the TLIF group (4 surgeons). Gender distribution was identical in the two groups (67% women); TS were significantly older than TLIF (67±10y and 56±15y respectively, p< 0.05). There were no significant group differences at baseline for any COMI domain scores (all p> 0.05). TS had a significantly lower operation duration (p=0.0001) and blood-loss (p=0.01) but a longer hospital stay (p=0.005) than TLIF. Complication rates prior to discharge were similar in each group (2–4%). 94% patients returned questionnaires at 12-months. The groups did not differ in: reduction in COMI score, 3.5±2.9 (TS) vs 4.1±2.6 (TLIF)(p=0.23); % good outcomes, 72% (TS) vs 77% (TLIF)(p=0.58); satisfaction with treatment, 82% (TS) vs 88% (TLIF) (p=0.36). Thus far, 75 patients have reached the 2-yr follow-up and the trend for no group differences remains: % good outcomes, 81% (TS) vs 79% (TLIF)(p=0.91); satisfaction with treatment, 83% (TS) vs 85% (TLIF) (p=0.88)

Discussion: This cohort study showed similar subjective results up to 2 years later for two different surgical techniques done for identical indications, but with differing surgical time, invasiveness and implant costs. The data thus far suggest that, for these degenerative disorders, optimal but invasive three-point stabilization is not required to achieve satisfactory results. Although the study design is not the highest in the “hierarchy-of-evidence”, it includes every single eligible patient and allows each surgeon to use his regular surgical procedure; it hence represents a practicable, complementary approach to the randomised-controlled-trial, with higher external validity (relevance/generalisability).


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 206 - 206
1 May 2006
Grob D
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Introduction Rheumatoid arthritis also affects the spine and creates conditions that need surgical treatment. As in other parts of the body, the maintenance of function and reduction of pain are primary goals of surgical treatment, however the additional threat to the neurological structures create an additional dimension in the surgical treatment of the spine.

Destructive processes of osteoligamentous structures and severe osteoporosis may be blamed as the principle cause for pain, deformity and subsequent neurological deficit in the rheumatoid patient’s spine. Cervical spine Atlantoaxial instability is the most frequently encountered pathology in the cervical spine of the rheumatoid patient. In order to avoid late appearance of myelopathy, the timing of surgery in the presence of significant atlantoaxial instability (ADD < 5mm) has to be carefully evaluated. The tendency is towards early surgical stabilization since no spontaneous improvement is to be expected in cases with aggressive rheumatoid arthritis. Late surgery not only carries the risk of causing myelopathy by repeated micro-trauma of the myelon, but also the need for extensive surgery including the occiput and the lower cervical spine in case of advanced destructive processes.

The subaxial cervical spine has a tendency to disintegrate in the presence of aggressive course of rheumatoid arthritis. The extent of instability and site of compression has to be carefully analyzed, using MRI and neurophysiological examinations. Due to weak bone structures anterior and posterior interventions are often necessary. Lumbar spine The rheumatoid pathology in the lumbar spine is mainly influenced by the degree of osteoporosis. Typical osteoporotic fractures, often on several levels, represent the most frequent pathology, which needs surgical help. In case of persistent pain the relatively new technique of vertebroplasty offers an elegant way to reduce pain. If severe deformities occur, the osteoporotic structure of bone limits the surgical possibility of correction of the deformity.

Conclusion “Wait and see”-policy in rheumatoid patients with spinal pathology is often not appropriate (as in other joints of the body) if function and neurology should be preserved and maintained. Early surgery represents usually minor intervention and is better tolerated than extensive corrections. Osteoporosis is the main limitation for surgical treatment in the rheumatoid spine.


The Journal of Bone & Joint Surgery British Volume
Vol. 73-B, Issue 6 | Pages 972 - 976
1 Nov 1991
Grob D Jeanneret B Aebi M Markwalder T

We reviewed 161 patients, from four centres in Switzerland, who had undergone posterior fusion of the upper cervical spine with transarticular screw fixation of the atlanto-axial joints. They were followed up for a mean 24.6 months. The vertebral artery and the medulla escaped injury and only 5.9% of the complications were directly related to the screws. The rate of pseudarthrosis was 0.6%.